CA3005247A1 - Antisense oligomers for treatment of polycystic kidney disease - Google Patents
Antisense oligomers for treatment of polycystic kidney disease Download PDFInfo
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- CA3005247A1 CA3005247A1 CA3005247A CA3005247A CA3005247A1 CA 3005247 A1 CA3005247 A1 CA 3005247A1 CA 3005247 A CA3005247 A CA 3005247A CA 3005247 A CA3005247 A CA 3005247A CA 3005247 A1 CA3005247 A1 CA 3005247A1
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- nucleobases
- mrna
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- retained intron
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562267252P | 2015-12-14 | 2015-12-14 | |
| US62/267,252 | 2015-12-14 | ||
| PCT/US2016/066417 WO2017106211A1 (en) | 2015-12-14 | 2016-12-13 | Antisense oligomers for treatment of polycystic kidney disease |
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| WO (1) | WO2017106211A1 (enrdf_load_stackoverflow) |
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| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| CA2963288A1 (en) | 2014-10-03 | 2016-04-07 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| WO2017060731A1 (en) | 2015-10-09 | 2017-04-13 | University Of Southampton | Modulation of gene expression and screening for deregulated protein expression |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| CA3005256A1 (en) | 2015-12-14 | 2017-06-22 | Cold Spring Harbor Laboratory | Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome |
| ES2965696T3 (es) | 2017-08-25 | 2024-04-16 | Stoke Therapeutics Inc | Oligómeros antisentido para el tratamiento de afecciones y enfermedades |
| JP2021523227A (ja) | 2018-05-04 | 2021-09-02 | ストーク セラピューティクス，インク． | コレステリルエステル蓄積症の処置のための方法及び組成物 |
| WO2021034985A1 (en) * | 2019-08-19 | 2021-02-25 | Stoke Therapeutics, Inc. | Compositions and methods for modulating splicing and protein expression |
| IL298063A (en) | 2020-05-11 | 2023-01-01 | Stoke Therapeutics Inc | Opa1 antisense oligomers for treatment of conditions and diseases |
| WO2024254639A1 (en) * | 2023-06-16 | 2024-12-19 | PYC Therapeutics Limited | Compositions and methods for treatment of kidney disease |
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| US20040102402A1 (en) * | 2002-11-22 | 2004-05-27 | Isis Pharmaceuticals Inc. | Modulation of tissue factor expression |
| US8007790B2 (en) * | 2006-04-03 | 2011-08-30 | Stowers Institute For Medical Research | Methods for treating polycystic kidney disease (PKD) or other cyst forming diseases |
| JP2009544314A (ja) * | 2006-07-24 | 2009-12-17 | アテナ ダイアグノスティックス，インコーポレイテッド | Ｐｋｄの変異およびその評価 |
| US20150141320A1 (en) * | 2012-05-16 | 2015-05-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating gene expression |
| WO2015035091A1 (en) * | 2013-09-04 | 2015-03-12 | Cold Spring Harbor Laboratory | Reducing nonsense-mediated mrna decay |
| CA2963288A1 (en) * | 2014-10-03 | 2016-04-07 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
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- 2016-12-13 WO PCT/US2016/066417 patent/WO2017106211A1/en active Application Filing
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| JP2018538287A (ja) | 2018-12-27 |
| EP3389782A1 (en) | 2018-10-24 |
| EP3389782A4 (en) | 2019-07-31 |
| JP2022046723A (ja) | 2022-03-23 |
| WO2017106211A1 (en) | 2017-06-22 |
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