CA3002962A1 - Protein quantitation in multicellular tissue specimens - Google Patents

Protein quantitation in multicellular tissue specimens Download PDF

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Publication number
CA3002962A1
CA3002962A1 CA3002962A CA3002962A CA3002962A1 CA 3002962 A1 CA3002962 A1 CA 3002962A1 CA 3002962 A CA3002962 A CA 3002962A CA 3002962 A CA3002962 A CA 3002962A CA 3002962 A1 CA3002962 A1 CA 3002962A1
Authority
CA
Canada
Prior art keywords
protein
component
biospecimen
heterogeneous
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3002962A
Other languages
English (en)
French (fr)
Inventor
Daniel C. Liebler
Lisa J. Zimmerman
Robbert J.C. Slebos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanderbilt University
Original Assignee
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanderbilt University filed Critical Vanderbilt University
Publication of CA3002962A1 publication Critical patent/CA3002962A1/en
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3002962A 2015-11-05 2016-04-20 Protein quantitation in multicellular tissue specimens Pending CA3002962A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562251604P 2015-11-05 2015-11-05
US62/251,604 2015-11-05
PCT/US2016/028426 WO2017078787A1 (en) 2015-11-05 2016-04-20 Protein quantitation in multicellular tissue specimens

Publications (1)

Publication Number Publication Date
CA3002962A1 true CA3002962A1 (en) 2017-05-11

Family

ID=58662934

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3002962A Pending CA3002962A1 (en) 2015-11-05 2016-04-20 Protein quantitation in multicellular tissue specimens

Country Status (5)

Country Link
US (1) US11047860B2 (https=)
EP (1) EP3371605B1 (https=)
JP (1) JP6742034B2 (https=)
CA (1) CA3002962A1 (https=)
WO (1) WO2017078787A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12523661B2 (en) 2019-09-19 2026-01-13 Janssen Biotech, Inc. Materials and methods for differential characterization of molecular conjugates and conjugation
MX2022016104A (es) * 2020-06-18 2023-02-01 Regeneron Pharma Enfoque de peptidos pesados para medir con precision lisina de extremo c-terminal sin procesar.
CN112150044B (zh) * 2020-11-04 2022-04-22 南京大学 基于高分辨率质谱的污水厂含氮有机物去除效果评价方法
US20240295561A1 (en) * 2021-06-17 2024-09-05 Konica Minolta, Inc. Quantification method and labeling method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5725481A (en) * 1996-05-17 1998-03-10 A. Fem Medical Corporation Method and apparatus for collecting vaginal fluid and exfoliated vaginal cells for diagnostic purposes
CA2550900A1 (en) * 2003-12-23 2005-07-07 Mount Sinai Hospital Methods for detecting markers associated with endometrial disease or phase
US20070019854A1 (en) * 2005-05-10 2007-01-25 Bioimagene, Inc. Method and system for automated digital image analysis of prostrate neoplasms using morphologic patterns
JP5240739B2 (ja) * 2007-04-13 2013-07-17 オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー
CA2749601C (en) 2009-01-14 2020-07-21 Stephen M. Hewitt Ratio based biomarkers and methods of use thereof
EP2309262A1 (en) 2009-10-06 2011-04-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method for quantifying biomolecules
US9777334B2 (en) 2012-04-30 2017-10-03 The Research Foundation for State University of New York Cancer blood test using BC200 RNA isolated from peripheral blood for diagnosis and treatment of invasive breast cancer
SG11201504241QA (en) * 2012-11-30 2015-06-29 Applied Proteomics Inc Method for evaluation of presence of or risk of colon tumors
EP3092495B1 (en) 2014-01-06 2020-11-25 Expression Pathology, Inc. Srm assay for pd-l1

Also Published As

Publication number Publication date
EP3371605A4 (en) 2019-05-01
WO2017078787A1 (en) 2017-05-11
EP3371605A1 (en) 2018-09-12
US11047860B2 (en) 2021-06-29
JP6742034B2 (ja) 2020-08-19
EP3371605B1 (en) 2021-06-23
US20190154699A1 (en) 2019-05-23
JP2018536175A (ja) 2018-12-06

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Effective date: 20210326