CA2995642A1 - Compositions and methods for treating ewing family tumors - Google Patents
Compositions and methods for treating ewing family tumors Download PDFInfo
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- CA2995642A1 CA2995642A1 CA2995642A CA2995642A CA2995642A1 CA 2995642 A1 CA2995642 A1 CA 2995642A1 CA 2995642 A CA2995642 A CA 2995642A CA 2995642 A CA2995642 A CA 2995642A CA 2995642 A1 CA2995642 A1 CA 2995642A1
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- tyrosine kinase
- kinase inhibitor
- biguanide compound
- imatinib
- metformin
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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Landscapes
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| US201562209197P | 2015-08-24 | 2015-08-24 | |
| US62/209,197 | 2015-08-24 | ||
| US201562209645P | 2015-08-25 | 2015-08-25 | |
| US62/209,645 | 2015-08-25 | ||
| PCT/US2016/047984 WO2017035057A1 (en) | 2015-08-24 | 2016-08-22 | Compositions and methods for treating ewing family tumors |
Publications (1)
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| CA2995642A1 true CA2995642A1 (en) | 2017-03-02 |
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| JP (1) | JP2018525413A (enExample) |
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| CA (1) | CA2995642A1 (enExample) |
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| WO (1) | WO2017035057A1 (enExample) |
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| CN108034726B (zh) * | 2018-01-18 | 2021-07-30 | 四川大学华西医院 | 检测mlh1表达水平的试剂在制备肿瘤靶向药敏感性检测试剂盒中的用途 |
| WO2022093789A1 (en) * | 2020-10-27 | 2022-05-05 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibitors of apex, alone and in combination with other cancer drugs to inhibit growth of cancer cells |
| WO2025097033A1 (en) * | 2023-11-01 | 2025-05-08 | City Of Hope | Metformin combination therapy for use in cancer treatment |
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| EP1641940A4 (en) | 2003-07-01 | 2009-09-02 | Mor Research Applic Ltd | DETERMINING PROGNOSIS IN PATIENTS WITH EWING SARCOMA BY GENETIC PROFILES |
| WO2008089034A2 (en) | 2007-01-11 | 2008-07-24 | Kemia, Inc. | Cytokine inhibitors |
| ES2594402T3 (es) * | 2009-10-21 | 2016-12-20 | Agios Pharmaceuticals, Inc. | Métodos y composiciones para trastornos relacionados con la proliferación celular |
| EP2509600B1 (en) | 2009-12-09 | 2017-08-02 | Agios Pharmaceuticals, Inc. | Therapeutically active compounds for use in the treatment of cancer characterized as having an idh mutation |
| EP3024456A4 (en) | 2013-07-26 | 2017-04-12 | Update Pharma Inc. | Combinatorial methods to improve the therapeutic benefit of bisantrene |
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2016
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- 2016-08-22 CA CA2995642A patent/CA2995642A1/en not_active Abandoned
- 2016-08-22 WO PCT/US2016/047984 patent/WO2017035057A1/en not_active Ceased
- 2016-08-22 US US15/755,258 patent/US10765675B2/en not_active Expired - Fee Related
- 2016-08-22 EP EP16839929.3A patent/EP3340978A4/en not_active Withdrawn
- 2016-08-22 JP JP2018510098A patent/JP2018525413A/ja active Pending
- 2016-08-23 TW TW105126878A patent/TW201717926A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20180243299A1 (en) | 2018-08-30 |
| JP2018525413A (ja) | 2018-09-06 |
| US10765675B2 (en) | 2020-09-08 |
| TW201717926A (zh) | 2017-06-01 |
| CN106714795A (zh) | 2017-05-24 |
| EP3340978A1 (en) | 2018-07-04 |
| WO2017035057A1 (en) | 2017-03-02 |
| EP3340978A4 (en) | 2019-04-10 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20220301 |