CA2991670A1 - Test genetique permettant de predire la resistance de l'espece enterobacter aux agents antimicrobiens - Google Patents
Test genetique permettant de predire la resistance de l'espece enterobacter aux agents antimicrobiens Download PDFInfo
- Publication number
- CA2991670A1 CA2991670A1 CA2991670A CA2991670A CA2991670A1 CA 2991670 A1 CA2991670 A1 CA 2991670A1 CA 2991670 A CA2991670 A CA 2991670A CA 2991670 A CA2991670 A CA 2991670A CA 2991670 A1 CA2991670 A1 CA 2991670A1
- Authority
- CA
- Canada
- Prior art keywords
- enc
- enterobacter
- antibiotic
- mutation
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/20—Sequence assembly
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne une méthode permettant de déterminer l'infection d'un patient par une espèce Enterobacter potentiellement résistante à un traitement médicamenteux antimicrobien, une méthode de sélection d'un traitement pour un patient atteint d'une infection à Enterobacter résistante aux antibiotiques, et une méthode permettant de déterminer un profil de résistance aux antibiotiques de micro-organismes bactériens appartenant à l'espèce Enterobacter, ainsi que les produits-programmes informatiques utilisés dans ces méthodes. Dans une méthode donnée à titre d'exemple, un échantillon (1) est utilisé pour un test moléculaire (2), et une empreinte moléculaire (3) est prise. Le résultat est ensuite comparé à une bibliothèque de référence (4) et le résultat (5) est généré.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2015/067382 WO2017016600A1 (fr) | 2015-07-29 | 2015-07-29 | Test génétique permettant de prédire la résistance de l'espèce enterobacter aux agents antimicrobiens |
EPPCT/EP2015/067382 | 2015-07-29 | ||
PCT/EP2016/067610 WO2017017044A1 (fr) | 2015-07-29 | 2016-07-25 | Test génétique permettant de prédire la résistance de l'espèce enterobacter aux agents antimicrobiens |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2991670A1 true CA2991670A1 (fr) | 2017-02-02 |
Family
ID=53762177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2991670A Abandoned CA2991670A1 (fr) | 2015-07-29 | 2016-07-25 | Test genetique permettant de predire la resistance de l'espece enterobacter aux agents antimicrobiens |
Country Status (6)
Country | Link |
---|---|
US (1) | US20180363030A1 (fr) |
EP (1) | EP3329008A1 (fr) |
CN (1) | CN108271400A (fr) |
AU (1) | AU2016299327A1 (fr) |
CA (1) | CA2991670A1 (fr) |
WO (2) | WO2017016600A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017016602A1 (fr) * | 2015-07-29 | 2017-02-02 | Curetis Gmbh | Test génétique pour prédire la résistance de l'espèce stenotrophomonas à des agents antimicrobiens |
CN112349350B (zh) * | 2020-11-09 | 2022-07-19 | 山西大学 | 基于一种杜氏藻核心基因组序列进行品系鉴定的方法 |
CN115807013B (zh) * | 2022-08-25 | 2023-11-21 | 四川大学华西医院 | 一种phoP基因突变体、应用及其验证方法 |
CN118028502B (zh) * | 2022-08-30 | 2024-07-26 | 四川大学华西医院 | 一类phoQ基因突变体、应用及其验证方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012027302A2 (fr) * | 2010-08-21 | 2012-03-01 | The Regents Of The University Of California | Systèmes et procédés de détection d'une résistance aux antibiotiques |
WO2012106432A2 (fr) * | 2011-02-01 | 2012-08-09 | Baylor College Of Medicine | Approche génomique de l'identification de marqueurs biologiques de la résistance et de la sensibilité à des antibiotiques dans des isolats cliniques de pathogènes bactériens |
CN104611422A (zh) * | 2015-01-09 | 2015-05-13 | 四川大学 | 一种检测大肠杆菌耐氟喹诺酮类gyrA、parC基因点突变方法 |
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2015
- 2015-07-29 WO PCT/EP2015/067382 patent/WO2017016600A1/fr active Application Filing
-
2016
- 2016-07-25 CN CN201680042236.9A patent/CN108271400A/zh active Pending
- 2016-07-25 WO PCT/EP2016/067610 patent/WO2017017044A1/fr active Application Filing
- 2016-07-25 EP EP16745674.8A patent/EP3329008A1/fr not_active Withdrawn
- 2016-07-25 AU AU2016299327A patent/AU2016299327A1/en not_active Abandoned
- 2016-07-25 CA CA2991670A patent/CA2991670A1/fr not_active Abandoned
- 2016-07-25 US US15/747,046 patent/US20180363030A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2017017044A1 (fr) | 2017-02-02 |
EP3329008A1 (fr) | 2018-06-06 |
CN108271400A (zh) | 2018-07-10 |
WO2017016600A1 (fr) | 2017-02-02 |
AU2016299327A1 (en) | 2018-02-01 |
US20180363030A1 (en) | 2018-12-20 |
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CA2991670A1 (fr) | Test genetique permettant de predire la resistance de l'espece enterobacter aux agents antimicrobiens | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |
Effective date: 20220301 |
|
FZDE | Discontinued |
Effective date: 20220301 |