CA2989926C - Non-carcinogenic cream for delivery of active ingredient into the dermis - Google Patents
Non-carcinogenic cream for delivery of active ingredient into the dermis Download PDFInfo
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- CA2989926C CA2989926C CA2989926A CA2989926A CA2989926C CA 2989926 C CA2989926 C CA 2989926C CA 2989926 A CA2989926 A CA 2989926A CA 2989926 A CA2989926 A CA 2989926A CA 2989926 C CA2989926 C CA 2989926C
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- SNBXCWVOMQIJEH-UHFFFAOYSA-K calcium;potassium;hydroxide;sulfate Chemical compound [OH-].[K+].[Ca+2].[O-]S([O-])(=O)=O SNBXCWVOMQIJEH-UHFFFAOYSA-K 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000010708 frostweed Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 230000009442 healing mechanism Effects 0.000 description 1
- 235000010181 horse chestnut Nutrition 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 238000013160 medical therapy Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The present document describes a non-carcinogenic cream for delivery of active ingredients in the dermis of a patient, which comprises a synergistic combination of .cndot. about 10 to 25% of oil .cndot. about 10 to 25% of emulsifier .cndot. about 1 to 12% of preservative .cndot. about 45 to 80% of water, aloe water or hamamelis water; and .cndot. about 1 to 25% of at least one homeopathic active ingredient chosen from pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum, rhododendron, benzoic acid, salicilicum acid, arnica montana, atropa belladonna, achillea millefolium, hamamelis, agaricus, aesculus, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, scrofularia nosada, pulsatilla, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, ranunculus, phytolacca decandra, dulcamara solanum, kalmia, actea racemosa, spigelia, gnaphalium, calendula officinalis, hepar sulphuris, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, petroleum or a synergistic combination thereof.
Description
File No. P4334CA00 Title: NON-CARCINOGENIC CREAM FOR DELIVERY OF ACTIVE
INGREDIENT INTO THE DERMIS
BACKGROUND
(a) Field [0001] The subject matter disclosed generally relates to a non-carcinogenic cream for delivery of active ingredients into the dermis of a patient for pain related to joint, lymphatic and blood circulation, nerve and skin.
(b) Related Prior Art
INGREDIENT INTO THE DERMIS
BACKGROUND
(a) Field [0001] The subject matter disclosed generally relates to a non-carcinogenic cream for delivery of active ingredients into the dermis of a patient for pain related to joint, lymphatic and blood circulation, nerve and skin.
(b) Related Prior Art
[0002] Many pharmaceutical analgesic topical compositions for treating muscular cramps, soreness and pain contain irritants, counter-irritants and toxic ingredients that are mostly carcinogenic and mask pain instead of alleviating it. These compositions irritate the skin and do not treat all the symptoms, causes pain and side effects and/or increase the risk of developing cancer.
[0003] Homeopathy is an ancient healing art and forms a vital part of medical therapy. The practice of homeopathy is widespread, particularly in eastern cultures and many European countries. Homeopathic medicine teaches the use of natural based remedies and, as such, provides an alternative to traditional allopathic medicine which relies heavily on the use of petrochemical based pharmaceuticals. There has been a large increase in interest in homeopathic medicine in the United States in recent years due, in large part, to a growing disenchantment with allopathic medications and the complications and side effects arising from their use. Frequently, the administration of allopathic medications results in serious side effects more deleterious to the patient than the basic condition being treated. Today, more and more individuals are looking for a gentler, safer path to good health free of the risks and side effects associated with traditional allopathic medicines.
[0004] In order to relieve pain in many inflammatory injuries or diseases it is desirable to promote healing, improve circulation to tissues nerves, provide anti-inflammatory activity, while alleviating pain instead of masking it.
File No. P4334CA00 Many injuries have a multiplicity of symptoms which require a cocktail of ingredients working together in order to provide relief.
File No. P4334CA00 Many injuries have a multiplicity of symptoms which require a cocktail of ingredients working together in order to provide relief.
[0005] Furthermore, it is desirable to obtain deep penetration of the active ingredients so as to act in the dermis to provide the proper response to cause healing of the injury and/or inflammation.
[0006] It is further desirable to provide an analgesic which does not rely upon counter-irritants that act by causing a superficial inflammation on the skin, which numbs the sensation of pain perceived by the sensory organ and results in only masking the pain instead of alleviating it.
[0007] It is further desirable to relax soft tissues, vasodilate blood vessels which are vasoconstricted so as to allow blood to flow normally, returning nutrients and oxygen to areas to promote healing. It is also desirable to release nerves which have been entrapped by hypercontraction of muscle tissue.
[0008] U.S. Pat. No. 5,162,037 to Whitson-Fischman discloses a method for treating pathogenic conditions of the body by preparing a homeopathic mixture of at least one herb or herbal extract which exhibits therapeutic property and add a magnetically permeable substance to the mixture, magnetizing the resulting mixture in a magnetic field during delivery to impart a substantially unipolar magnetic charge on said mixture; and administering the magnetized mixture through one or more specific acupuncture points of the body which are associated with producing a desired response to the particular condition being treated.
[0009] U.S. Pat. No. 5,795,573 to Paradise discloses homeopathic topical anti-inflammatory and pain relieving compositions. Although the compositions active ingredients include homeopathic extracts from Arnica Montana, Rhus toxicodendron and Aesculus hippocastanum and belladonna, they also include carcinogenic ingredients such as PEG, PPG, ethoxydiglycol, paraben, isopropyl myristate and Dowicil 200TM
Date Recue/Date Received 2022-09-29 File No. P4334CA00
Date Recue/Date Received 2022-09-29 File No. P4334CA00
[0010] Finally, it is highly desirable to have a non-carcinogenic cream for the treatment of pain.
SUMMARY
SUMMARY
[0011] It is an object of the present disclosure to provide a non-carcinogenic cream for delivery of active ingredients in the dermis of a patient for pain related to joint, lymphatic and blood circulation, nerve and skin.
[0012] According to an embodiment, there is provided a non-carcinogenic cream for delivery of active ingredients in the dermis of a patient, comprises a synergistic combination of = about 10 to 25% of oil = about 10 to 25 of emulsifier = about 1 to 12% of preservative = about 45 to 80% of water, aloe water or hamamelis water, and = about 1 to 25% of at least one homeopathic active ingredient chosen from pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum, rhododendron, benzoic acid, salicilicum acid, arnica montana, atropa belladonna, achillea millefolium, hamamelis, agaricus, aesculus, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, scrofularia nosada, pulsatilla, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, ranunculus, phytolacca decandra, dulcamara solanum, kalmia, actea racemosa, spigelia, gnaphalium, calendula officinalis, hepar sulphuris, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, petroleum or a synergistic combination thereof.
[0013] The oil is chosen from emu oil, olive oil, argan nut oil, sunflower/safflower oil, coconut oil, castor oil, avocado oil, jojoba oil, lavender oil, grape seed oil, poppy seed oil, sunflower oil or wheat germ oil.
[0014] The emulsifier is chosen from oleyl oleate, cetearyl alcohol, cetearyl wheat straw glucosides, glyceryl stearate, sodium stearoyl lactylate, File No. P4334CA00 cetearyl olivate, sorbitan olivate, propylene glycol esters (pgms), borax with bees wax, bees wax, BTMS 25%, carbomer, emulsifying wax¨NF, lecithin, stearate, silky emulsifying wax, stearyl alcohol NF, shea butter, cocoa butter, coconut oil or stearic acid.
[0015] The preservative is chosen from a combination of glucose, glucose oxidase and lactoperoxidase (BiovertTM enzymes), a combination of benzyl alcohol, salicylic acid, glycerin and sorbic acid (GeoguardTM ECT), polylysine, natamycin, nisin, isothiazolinones, benzoic acid ¨ sodium benzoate, sorbic acid - potassium sorbate, levulinic acid, anisic acid, rosemary oil extract, grapefruit seed extract, T-50 vitamin E oil, jermaben 11, or jermaben 11-E.
[0016] The non-carcinogenic cream for improving joint conditions contains at least one homeopathic active ingredient chosen from pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum, rhododendron, benzoic acid, salicilicum acid or a synergistic combination thereof.
[0017] The non-carcinogenic cream for improving blood circulation contains at least one homeopathic active ingredient chosen from arnica montana, atropa belladonna, achillea millefolium, hamamelis, agaricus, aesculus or a synergistic combination thereof.
[0018] The non-carcinogenic cream for improving lymphatic circulation contains at least one homeopathic active ingredient chosen from mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, gallium aparine, phytolacca decandra, scrofularia nosada, pulsatilla or a synergistic combination thereof.
[0019] The non-carcinogenic cream for improving sensitive nerves contains at least one homeopathic active ingredient chosen from aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, File No. P4334CA00 ranunculus, phytolacca decandra, dulcamara solanum, kalmia, actea racemosa, spigelia, gnaphalium or a synergistic combination thereof.
[0020] The non-carcinogenic cream for reducing scars and/or keloids of the skin contains at least one homeopathic active ingredient chosen from pancreatinum, calendula officinalis, hepar sulphuris, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, petroleum or a synergistic combination thereof.
[0021] The preferred non-carcinogenic cream comprises = about 14.7% of oil;
= about 12.8% of emulsifier;
= about 1.05% of preservative; and = about 65.67% of water; and = about 4.78% the homeopathic active ingredient comprises at least pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, arnica montana, atropa belladonna, achillea millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, calendula officinalis and hepar sulphur's.
= about 12.8% of emulsifier;
= about 1.05% of preservative; and = about 65.67% of water; and = about 4.78% the homeopathic active ingredient comprises at least pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, arnica montana, atropa belladonna, achillea millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, calendula officinalis and hepar sulphur's.
[0022] According to another embodiment, there is provided a non-carcinogenic cream for delivery of active ingredients in the dermis of a patient comprises a synergistic combination of = about 10 to 25% of oil = about 10 to 25 of emulsifier = about 1 to 12% of preservative = about 45 to 80% of water, aloe water or hamamelis water, and = about 1 to 25% of a synergistic combination of at least five homeopathic active ingredients comprising File No. P4334CA00 O from at least one of aconitum napellus, hypericum perforatum, bellis a first ingredient chosen from at least one of ruts graveolens, ledum palustre, colchicum autumnale or symphytum officinalis;
O a second ingredient chosen from at least one of arnica montana, atropa belladonna, achillea millefolium or hamamelis;
O a third ingredient chosen from at least one of mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia or echinacea purpurea;
O a fourth ingredient chosen from at least one perennis, matricaria chamomilla, gallium aparine, phytolacca decandra, scrofularia nosada, or pulsatilla;
O a fifth ingredient chosen from at least one of pancreatinum, calendula officinalis, hepar sulphuris, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, or petroleum.
O a second ingredient chosen from at least one of arnica montana, atropa belladonna, achillea millefolium or hamamelis;
O a third ingredient chosen from at least one of mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia or echinacea purpurea;
O a fourth ingredient chosen from at least one perennis, matricaria chamomilla, gallium aparine, phytolacca decandra, scrofularia nosada, or pulsatilla;
O a fifth ingredient chosen from at least one of pancreatinum, calendula officinalis, hepar sulphuris, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, or petroleum.
[0023] Features and advantages of the subject matter hereof will become more apparent in light of the following detailed description of selected embodiments, as illustrated in the accompanying figures. As will be realized, the subject matter disclosed and claimed is capable of modifications in various respects, all without departing from the scope of the claims.
Accordingly, the drawings and the description are to be regarded as illustrative in nature, and not as restrictive and the full scope of the subject matter is set forth in the claims.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
Accordingly, the drawings and the description are to be regarded as illustrative in nature, and not as restrictive and the full scope of the subject matter is set forth in the claims.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0024] According to the invention, there is provided a non-carcinogenic cream for topical application for delivery of active ingredients in the dermis of a patient for pain related to joint, lymphatic and blood circulation, nerve and skin.
[0025] The composition can be used in combination with an occlusive bandage.
File No. P4334CA00
File No. P4334CA00
[0026] It has been found that the non-carcinogenic cream for delivery of active ingredients in the dermis of a patient for treating pain, includes a synergistic combination of = about 10 to 25% of oil = about 10 to 25% of emulsifier = about 1 to 12% of preservative = about 45 to 80% of water, aloe water or hamamelis water; and = about 1 to 25% of at least one homeopathic active ingredient chosen from pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, arnica montana, atropa belladonna, achillea millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, calendula officinalis, hepar sulphuris or a synergistic combination thereof.
[0027] Although greater amounts of the homeopathic active ingredient can be used in the composition it has been found that about 2 to 25% by weight of the combination of extracts is effective.
[0028] The compositions of the invention can be used in combination with other herbs or herbal extracts. For example, it may be desirable to thin the blood or to better promote circulation such as Naja and Gratalus horridum.
[0029] To condition the skin graphite and/or trace minerals such as copper and zinc salts may be included.
[0030] Other anti-inflammatory agents such as Lachesis Ninta that contains enzymes which relieves muscle tightness and cramps can be included in the composition.
[0031] The combinations as used herein stimulate the body's self healing mechanism by promoting circulation in the micro-capillary system.
This restores blood flow to the inflammed areas where most of the pain is File No. P4334CA00 realized. When blood flow is improved to an ailing joint, healing begins and true pain relief is realized.
This restores blood flow to the inflammed areas where most of the pain is File No. P4334CA00 realized. When blood flow is improved to an ailing joint, healing begins and true pain relief is realized.
[0032] The compositions of the invention may include other plant or herbal extracts. For example, there may be utilized extracts of Paraguay tea, Kola and Guarana which provide a source of methylxanthines, saponius, tannins and glycosides which have been shown to reduce swelling and redness. The extract of Paraguay tea is known as "Mate extract" and is described in the "International Cosmetic Ingredient Dictionary", 5th Edition.
Mate extract is commercially available in combination with extracts of Kola and Guarana which is sold by Cosmetic Ingredient Resources of Stamford under the trademark "QUENCHT."
Mate extract is commercially available in combination with extracts of Kola and Guarana which is sold by Cosmetic Ingredient Resources of Stamford under the trademark "QUENCHT."
(0033] Suitable herbs which can be used also include symphytum, officianalis, Moschus moscheferous, Cow bezoar, Pripalia geniculata, Plantago asiatica, Causticum, Helianthemum canadense, Ornithogalum umbellatum, Clematis crispa, Impatiens pallida, Prunus Cerasus, and the like.
[0034] The present invention will be more readily understood by referring to the following examples which are given to illustrate the invention rather than to limit its scope. The amounts indicated are by weight percent unless otherwise noted.
Cream to treat pain
Cream to treat pain
(0035] A non-carcinogenic cream is prepared by admixing the following ingredients.
= 12.7% of a synergistic combination of emu oil, olive oil, argan nut oil, sunflower/safflower oil and coconut oil;
= 15.8% of a synergistic combination of coleyl oleate and cetearyl alcohol;
= 1.05% of a synergistic combination of glucose, glucose oxidase and lactoperoxidase;
File No. P4334CA00 = 65.67% of water and = 4.78% of a combination of homeopathic extracts containing:
O 0.05 % by weight of pancreatinum, O 0.01% by weight of ruta graveolens, O 0.01% by weight of ledum palustre, O 0.1% by weight of colchicum autumnale, O 0.1% by weight of symphytum officinal's, O 1.5% by weight of arnica montana, O 0.5% by weight of atropa belladonna, O 0.07% by weight of achillea millefolium, O 0.45% by weight of hamamelis, O 0.04% by weight of mercurius solubilis, O 0.01% by weight of mercurius iodatus, O 0.1% by weight of conium maculatum, o 0.15% by weight of echinacea angustifolia, O 0.15% by weight of echinacea purpurea, O 0.5% by weight of aconitum napellus, O 0.09% by weight of hypericum perforatum, o 0.1% by weight of bellis perennis, O 0.15% by weight of matricaria chamomilla, O 0.45% by weight of calendula officinalis and O 0.25% by weight of hepar sulphuris.
Cream to treat pain File No. P4334CA00
= 12.7% of a synergistic combination of emu oil, olive oil, argan nut oil, sunflower/safflower oil and coconut oil;
= 15.8% of a synergistic combination of coleyl oleate and cetearyl alcohol;
= 1.05% of a synergistic combination of glucose, glucose oxidase and lactoperoxidase;
File No. P4334CA00 = 65.67% of water and = 4.78% of a combination of homeopathic extracts containing:
O 0.05 % by weight of pancreatinum, O 0.01% by weight of ruta graveolens, O 0.01% by weight of ledum palustre, O 0.1% by weight of colchicum autumnale, O 0.1% by weight of symphytum officinal's, O 1.5% by weight of arnica montana, O 0.5% by weight of atropa belladonna, O 0.07% by weight of achillea millefolium, O 0.45% by weight of hamamelis, O 0.04% by weight of mercurius solubilis, O 0.01% by weight of mercurius iodatus, O 0.1% by weight of conium maculatum, o 0.15% by weight of echinacea angustifolia, O 0.15% by weight of echinacea purpurea, O 0.5% by weight of aconitum napellus, O 0.09% by weight of hypericum perforatum, o 0.1% by weight of bellis perennis, O 0.15% by weight of matricaria chamomilla, O 0.45% by weight of calendula officinalis and O 0.25% by weight of hepar sulphuris.
Cream to treat pain File No. P4334CA00
[0036] A non-carcinogenic cream is prepared by admixing the following ingredients.
= 14.7% of a synergistic combination of emu oil, olive oil, argon nut oil, sunflower/safflower oil and coconut oil;
= 12.8% of a synergistic combination of oleyl oleate and cetearyl alcohol;
= 1.05% of a synergistic combination of benzyl alcohol, salicylic acid, glycerin and sorbic acid;
= 65.67% of water and = 4.78% of a combination of homeopathic extracts containing:
O 0.05 % by weight of pancreatinum, O 0.01% by weight of ruta graveolens, o 0.01% by weight of ledum palustre, O 0.1% by weight of colchicum autumnale, O 0.1% by weight of symphytum offleinalis, o 1.5% by weight of arnica montana, O 0.5% by weight of atropa belladonna, O 0.07% by weight of achillea millefolium, = 0.45% by weight of hamamelis, O 0.04% by weight of mercurius solubilis, O 0.01% by weight of mercurius iodatus, O 0.1% by weight of conium maculatum, O 0.15% by weight of echinacea angustifolia, O 0.15% by weight of echinacea purpurea, O 0.5% by weight of aconitum napellus, O 0.09% by weight of hypericum perforatum, File No. P4334CA00 O 0.1% by weight of bellis perennis, o 0.15% by weight of matricaria chamomilla, O 0.45% by weight of calendula officinalis and O 0.25% by weight of hepar sulphuris.
While preferred embodiments have been described above and illustrated in the accompanying drawings, it will be evident to those skilled in the art that modifications may be made without departing from this disclosure. Such modifications are considered as possible variants comprised in the scope of the disclosure.
= 14.7% of a synergistic combination of emu oil, olive oil, argon nut oil, sunflower/safflower oil and coconut oil;
= 12.8% of a synergistic combination of oleyl oleate and cetearyl alcohol;
= 1.05% of a synergistic combination of benzyl alcohol, salicylic acid, glycerin and sorbic acid;
= 65.67% of water and = 4.78% of a combination of homeopathic extracts containing:
O 0.05 % by weight of pancreatinum, O 0.01% by weight of ruta graveolens, o 0.01% by weight of ledum palustre, O 0.1% by weight of colchicum autumnale, O 0.1% by weight of symphytum offleinalis, o 1.5% by weight of arnica montana, O 0.5% by weight of atropa belladonna, O 0.07% by weight of achillea millefolium, = 0.45% by weight of hamamelis, O 0.04% by weight of mercurius solubilis, O 0.01% by weight of mercurius iodatus, O 0.1% by weight of conium maculatum, O 0.15% by weight of echinacea angustifolia, O 0.15% by weight of echinacea purpurea, O 0.5% by weight of aconitum napellus, O 0.09% by weight of hypericum perforatum, File No. P4334CA00 O 0.1% by weight of bellis perennis, o 0.15% by weight of matricaria chamomilla, O 0.45% by weight of calendula officinalis and O 0.25% by weight of hepar sulphuris.
While preferred embodiments have been described above and illustrated in the accompanying drawings, it will be evident to those skilled in the art that modifications may be made without departing from this disclosure. Such modifications are considered as possible variants comprised in the scope of the disclosure.
Claims (6)
1. A
cream for delivery of active ingredients in the derm is of a patient, which comprises a combination of = about 10 to about 25% by weight of oil = about 10 to about 25% by weight of emulsifier = about 1 to about 12% by weight of preservative = about 45 to about 80% by weight of water, aloe water or hamamelis water;
and = about 1 to about 25% by weight of a combination of at least five homeopathic active ingredients comprising:
O a first ingredient for improving joint conditions chosen from one of ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum, rhododendron, benzoic acid, salicilicum acid or a combination thereof;
O a second ingredient for improving blood circulation chosen from one of arnica montana, atropa belladonna, achillea millefolium, hamamelis, agaricus, aesculus or a combination thereof;
O a third ingredient for improving lymphatic circulation chosen from one of mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, gallium aparine, phytolacca decandra, scrofularia nosada, pulsatilla, or a combination thereof;
O a fourth ingredient for improving sensitive nerves chosen from aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, ranunculus, phytolacca decandra, dulcamara solanum, kalmia, actea racemosa, spigelia, gnaphalium, or a combination thereof; and O a fifth ingredient for reducing scars and/or keloids of the skin chosen from pancreatinum, calendula officinalis, hepar sulphuric, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, petroleum or a combination thereof.
Date recue/Date received 2023-06-05
cream for delivery of active ingredients in the derm is of a patient, which comprises a combination of = about 10 to about 25% by weight of oil = about 10 to about 25% by weight of emulsifier = about 1 to about 12% by weight of preservative = about 45 to about 80% by weight of water, aloe water or hamamelis water;
and = about 1 to about 25% by weight of a combination of at least five homeopathic active ingredients comprising:
O a first ingredient for improving joint conditions chosen from one of ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum, rhododendron, benzoic acid, salicilicum acid or a combination thereof;
O a second ingredient for improving blood circulation chosen from one of arnica montana, atropa belladonna, achillea millefolium, hamamelis, agaricus, aesculus or a combination thereof;
O a third ingredient for improving lymphatic circulation chosen from one of mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, gallium aparine, phytolacca decandra, scrofularia nosada, pulsatilla, or a combination thereof;
O a fourth ingredient for improving sensitive nerves chosen from aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, ranunculus, phytolacca decandra, dulcamara solanum, kalmia, actea racemosa, spigelia, gnaphalium, or a combination thereof; and O a fifth ingredient for reducing scars and/or keloids of the skin chosen from pancreatinum, calendula officinalis, hepar sulphuric, somniferrum, calcarea fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica urens, aloe, graphite, petroleum or a combination thereof.
Date recue/Date received 2023-06-05
2. The cream of claim 1, wherein the oil is at least one oil chosen from emu oil, olive oil, argan nut oil, sunflower/safflower oil, coconut oil, castor oil, avocado oil, jojoba oil, lavender oil, grape seed oil, poppy seed oil, sunflower oil or wheat germ oil.
3. The cream of any one of claims 1 to 2, wherein the emulsifier is at least one chosen from oleyl oleate, cetearyl alcohol, cetearyl wheat straw glucosides, glyceryl stearate, sodium stearoyl lactylate, cetearyl olivate, sorbitan olivate, propylene glycol esters, borax with bees wax, bees wax, BTMS 25%, carbomer, emulsifying wax¨NF, lecithin, stearate, silky emulsifying wax, stearyl alcohol NF, shea butter, cocoa butter, coconut oil or stearic acid.
4. The cream of any one of claims 1 to 3, wherein the preservative is at least one chosen from a combination of glucose, glucose oxidase and lactoperoxidase, a combination of benzyl alcohol, salicylic acid, glycerin and sorbic acid, polylysine, natamycin, nisin, isothiazolinones, benzoic acid ¨ sodium benzoate, sorbic acid -potassium sorbate, levulinic acid, anisic acid, rosemary oil extract, grapefruit seed extract, T-50 vitamin E oil, germaben TM 11, or germaben TM 11-E.
5. The cream of any one of claims 1 to 4, which comprises = about 14% by weight of oil;
= about 14% by weight of emulsifier;
= about 1% by weight of preservative; and = about 66% by weight of water; and = about 5% by weight of the homeopathic active ingredient which comprises at least pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, arnica montana, atropa belladonna, achillea millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, calendula officinalis and hepar sulphuris.
Date recue/Date received 2023-06-05
= about 14% by weight of emulsifier;
= about 1% by weight of preservative; and = about 66% by weight of water; and = about 5% by weight of the homeopathic active ingredient which comprises at least pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale, symphytum officinalis, arnica montana, atropa belladonna, achillea millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus, hypericum perforatum, bellis perennis, matricaria chamomilla, calendula officinalis and hepar sulphuris.
Date recue/Date received 2023-06-05
6.
Use of the cream of any one of claims 1-5 as a topical-based treatment for improving joint conditions, blood circulation, lymphatic circulation, sensitive nerves, and reducing scars and/or keloids of the skin and promoting granulation tissue growth wherein - joint conditions in a patient comprises pain, stiffness, sprain, strain, swelling, inflammation, wound and injury;
- blood circulation in a patient comprises pain, muscle elongations and/or contractions, congestion, capillary distension, swelling, inflammation, bruise, wound and injury;
- lymphatic circulation in a patient comprises pain, congestion of lymphatic system, glandular swelling, bruise, stiffness, muscular weakness, lymphatic inflammation, wound and injury; and - sensitive nerves conditions in a patient comprises pain, joint swelling, irritation in joint and/or muscle, nerve contraction, wound and injury.
Date Recue/Date Received 2023-09-20
Use of the cream of any one of claims 1-5 as a topical-based treatment for improving joint conditions, blood circulation, lymphatic circulation, sensitive nerves, and reducing scars and/or keloids of the skin and promoting granulation tissue growth wherein - joint conditions in a patient comprises pain, stiffness, sprain, strain, swelling, inflammation, wound and injury;
- blood circulation in a patient comprises pain, muscle elongations and/or contractions, congestion, capillary distension, swelling, inflammation, bruise, wound and injury;
- lymphatic circulation in a patient comprises pain, congestion of lymphatic system, glandular swelling, bruise, stiffness, muscular weakness, lymphatic inflammation, wound and injury; and - sensitive nerves conditions in a patient comprises pain, joint swelling, irritation in joint and/or muscle, nerve contraction, wound and injury.
Date Recue/Date Received 2023-09-20
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| Application Number | Priority Date | Filing Date | Title |
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| CA2989926A CA2989926C (en) | 2017-12-22 | 2017-12-22 | Non-carcinogenic cream for delivery of active ingredient into the dermis |
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| CA2989926A CA2989926C (en) | 2017-12-22 | 2017-12-22 | Non-carcinogenic cream for delivery of active ingredient into the dermis |
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