CA2985090C - Application medicales et veterinaires de lumiere a des composes therapeutiques - Google Patents
Application medicales et veterinaires de lumiere a des composes therapeutiques Download PDFInfo
- Publication number
- CA2985090C CA2985090C CA2985090A CA2985090A CA2985090C CA 2985090 C CA2985090 C CA 2985090C CA 2985090 A CA2985090 A CA 2985090A CA 2985090 A CA2985090 A CA 2985090A CA 2985090 C CA2985090 C CA 2985090C
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- Prior art keywords
- light
- solution
- fiber optic
- antimicrobial
- optic cable
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- 229940088710 antibiotic agent Drugs 0.000 description 4
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- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinic acid amide Natural products NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 3
- 150000002978 peroxides Chemical class 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 description 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 2
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- 239000005639 Lauric acid Substances 0.000 description 2
- TUNFSRHWOTWDNC-UHFFFAOYSA-N Myristic acid Natural products CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 2
- 235000021360 Myristic acid Nutrition 0.000 description 2
- 102100040247 Tumor necrosis factor Human genes 0.000 description 2
- UFUVLHLTWXBHGZ-MGZQPHGTSA-N [(2r,3r,4s,5r,6r)-6-[(1s,2s)-2-chloro-1-[[(2s,4r)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] dihydrogen phosphate Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@@H](SC)O1 UFUVLHLTWXBHGZ-MGZQPHGTSA-N 0.000 description 2
- 230000003444 anaesthetic effect Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 229960002227 clindamycin Drugs 0.000 description 2
- KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 description 2
- 229960002291 clindamycin phosphate Drugs 0.000 description 2
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- CMCBDXRRFKYBDG-UHFFFAOYSA-N 1-dodecoxydodecane Chemical class CCCCCCCCCCCCOCCCCCCCCCCCC CMCBDXRRFKYBDG-UHFFFAOYSA-N 0.000 description 1
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- 108090000695 Cytokines Proteins 0.000 description 1
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- 241000283086 Equidae Species 0.000 description 1
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- XMEVHPAGJVLHIG-FMZCEJRJSA-N chembl454950 Chemical compound [Cl-].C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H]([NH+](C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O XMEVHPAGJVLHIG-FMZCEJRJSA-N 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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- 230000003612 virological effect Effects 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D9/00—Bandages, poultices, compresses specially adapted to veterinary purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0616—Skin treatment other than tanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/0606—Mouth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0645—Applicators worn by the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Radiation-Therapy Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Laser Surgery Devices (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Abstract
Il est décrit des applications médicales et vétérinaires de la lumière aux composés thérapeutiques comprenant un agent de retenue de solution adapté pour retenir une solution thérapeutique contre un tissu dun utilisateur, un câble à fibres optiques, une source lumineuse qui se connecte au câble à fibres optiques et fournit une lumière dune longueur donde prédéterminée au câble à fibres optiques, et une terminaison lumineuse sur le câble de fibre optique qui expose la lumière à la solution thérapeutique. Une formulation comprend un comburant, la solution thérapeutique ayant une efficacité thérapeutique initiale et une lumière dune fréquence prédéterminée qui subit une réaction synergique avec le comburant, améliorant ainsi lefficacité thérapeutique initiale de la solution.
Applications Claiming Priority (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462026498P | 2014-07-18 | 2014-07-18 | |
US62/026,498 | 2014-07-18 | ||
US14/497,269 | 2014-09-25 | ||
US14/497,269 US9579177B2 (en) | 2014-07-18 | 2014-09-25 | Dental and medical devices with light source and antimicrobial solution |
US14/536,633 | 2014-11-09 | ||
US14/536,633 US9504848B2 (en) | 2014-07-18 | 2014-11-09 | Medical devices with a light source and antimicrobial solution |
US14/583,580 | 2014-12-26 | ||
US14/583,580 US9931189B2 (en) | 2014-07-18 | 2014-12-26 | Veterinary devices with a light source and antimicrobial solution |
US14/630,513 | 2015-02-24 | ||
US14/630,513 US9700735B2 (en) | 2014-07-18 | 2015-02-24 | Medical and veterinary applications of light to antimicrobial and antineoplastic chemicals |
US14/638,902 US10016456B2 (en) | 2014-07-18 | 2015-03-04 | Methods for treating acne vulgaris |
US14/638,902 | 2015-03-04 | ||
US14/697,579 US20160015745A1 (en) | 2014-07-18 | 2015-04-27 | Formulations of Antimicrobial, Antiviral, and Antineoplastic Compounds In Combination With Certain Wavelengths of Light |
US14/697,579 | 2015-04-27 | ||
CA2954886A CA2954886C (fr) | 2014-07-18 | 2015-07-07 | Application medicales et veterinaires de lumiere a des composes therapeutiques |
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AU (1) | AU2015290092B2 (fr) |
CA (2) | CA2954886C (fr) |
WO (1) | WO2016010765A1 (fr) |
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CN108853750B (zh) * | 2018-07-16 | 2020-03-20 | 北京大学口腔医学院 | 穿戴式光疗设备 |
CN109009549B (zh) * | 2018-08-20 | 2024-06-28 | 中国人民解放军军事科学院军事医学研究院 | 记录动物药物成瘾行为及相关脑区神经活动规律的装置 |
DE102020111257A1 (de) | 2020-04-24 | 2021-10-28 | Jessika Kähler | Anordnung zur Photobiomodulation eines Lebewesens |
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US4898439A (en) * | 1988-02-10 | 1990-02-06 | Kei Mori | Light radiation device for use in medical treatment |
AU3578497A (en) * | 1996-08-08 | 1998-03-06 | Light Sciences Limited Partnership | Method and apparatus to treat gingival and periodontal disease |
US6254391B1 (en) * | 1997-11-22 | 2001-07-03 | Daniel Henry Darnell | Device for heating the teeth and uses therefor |
CN1269468C (zh) * | 2001-01-29 | 2006-08-16 | 三菱瓦斯化学株式会社 | 牙齿漂白剂和牙齿漂白方法 |
ATE525095T1 (de) * | 2002-01-08 | 2011-10-15 | Bernard Technologies Inc | Antimikrobielle körperbedeckungsartikel |
US6893259B1 (en) * | 2004-03-08 | 2005-05-17 | Igor Reizenson | Oral hygiene device and method of use therefor |
SG140589A1 (en) * | 2004-08-06 | 2008-03-28 | Pharos Life Corp | Therapy device and related accessories, compositions, and treatment methods |
GB0423332D0 (en) * | 2004-10-21 | 2004-11-24 | Dezac Ltd | Tooth whitening apparatus and methods |
JP2006271831A (ja) * | 2005-03-30 | 2006-10-12 | Terumo Corp | 医療用治療装置およびその装置の使用方法 |
AU2006249760C1 (en) * | 2005-05-25 | 2010-11-04 | Biolase, Inc. | Device having activated textured surfaces for treating oral tissue |
CA2632183A1 (fr) * | 2005-08-25 | 2007-03-01 | Philip R. Houle | Solutions sensibilisantes ameliorees, systemes, et procedes d'utilisation |
US8057464B2 (en) * | 2006-05-03 | 2011-11-15 | Light Sciences Oncology, Inc. | Light transmission system for photoreactive therapy |
EP3205355A1 (fr) * | 2008-11-07 | 2017-08-16 | KLOX Technologies, Inc. | Combinaison d'un oxydant et d'un photoactivateur |
US8771741B2 (en) * | 2009-01-23 | 2014-07-08 | The Penn State Research Foundation | In vivo photodynamic therapy of cancer via a near infrared agent encapsulated in calcium phosphate nanoparticles |
JP2012532103A (ja) * | 2009-06-30 | 2012-12-13 | スリーエム イノベイティブ プロパティズ カンパニー | 光活性化抗菌性物品及び使用方法 |
JP6246468B2 (ja) * | 2010-03-11 | 2017-12-13 | メルク パテント ゲーエムベーハー | 治療および化粧品におけるファイバー |
US8591229B2 (en) * | 2010-12-16 | 2013-11-26 | Duane C. Keller | Devices and methods for creating a positive pressure environment for treatment of oral biofilms associated with periodontal disease |
US20150072302A1 (en) * | 2013-04-19 | 2015-03-12 | Jasibo, LLC. | Light activated tooth whitening composition |
US20150045720A1 (en) * | 2013-08-08 | 2015-02-12 | A-Z Ltd. | Method for treating local infection |
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EP3169400A1 (fr) | 2017-05-24 |
AU2015290092B2 (en) | 2018-08-16 |
WO2016010765A1 (fr) | 2016-01-21 |
CN106659902A (zh) | 2017-05-10 |
KR20170019383A (ko) | 2017-02-21 |
CA2954886A1 (fr) | 2016-01-21 |
EP3169400A4 (fr) | 2018-04-11 |
CA2954886C (fr) | 2020-06-30 |
JP2018501829A (ja) | 2018-01-25 |
AU2015290092A1 (en) | 2017-01-12 |
CA2985090A1 (fr) | 2016-01-21 |
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