CA2946928C - Treatment and prevention of alzheimer's disease (ad) - Google Patents

Treatment and prevention of alzheimer's disease (ad) Download PDF

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Publication number
CA2946928C
CA2946928C CA2946928A CA2946928A CA2946928C CA 2946928 C CA2946928 C CA 2946928C CA 2946928 A CA2946928 A CA 2946928A CA 2946928 A CA2946928 A CA 2946928A CA 2946928 C CA2946928 C CA 2946928C
Authority
CA
Canada
Prior art keywords
use according
patient
aluminium oxyhydroxide
aluminium
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2946928A
Other languages
English (en)
French (fr)
Other versions
CA2946928A1 (en
Inventor
Markus Mandler
Achim Schneeberger
Arne Von Bonin
Frank Mattner
Walter Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advantage Therapeutics Inc
Original Assignee
Advantage Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advantage Therapeutics Inc filed Critical Advantage Therapeutics Inc
Publication of CA2946928A1 publication Critical patent/CA2946928A1/en
Application granted granted Critical
Publication of CA2946928C publication Critical patent/CA2946928C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2946928A 2014-04-29 2015-04-29 Treatment and prevention of alzheimer's disease (ad) Active CA2946928C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14166354.2 2014-04-29
EP14166355.9 2014-04-29
EP14166355 2014-04-29
EP14166354 2014-04-29
PCT/EP2015/059339 WO2015165966A1 (en) 2014-04-29 2015-04-29 Treatment and prevention of alzheimer's disease (ad)

Publications (2)

Publication Number Publication Date
CA2946928A1 CA2946928A1 (en) 2015-11-05
CA2946928C true CA2946928C (en) 2023-01-31

Family

ID=53039896

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2946928A Active CA2946928C (en) 2014-04-29 2015-04-29 Treatment and prevention of alzheimer's disease (ad)

Country Status (18)

Country Link
US (1) US10478454B2 (enExample)
EP (2) EP3269376B1 (enExample)
JP (1) JP6692755B2 (enExample)
KR (1) KR102388363B1 (enExample)
CN (1) CN106659738B (enExample)
AU (1) AU2015254663B2 (enExample)
CA (1) CA2946928C (enExample)
CY (1) CY1119674T1 (enExample)
DK (1) DK3137093T3 (enExample)
ES (2) ES2824763T3 (enExample)
HR (1) HRP20171896T1 (enExample)
HU (1) HUE037501T2 (enExample)
LT (1) LT3137093T (enExample)
NO (1) NO3137093T3 (enExample)
PL (1) PL3137093T3 (enExample)
PT (1) PT3137093T (enExample)
SI (1) SI3137093T1 (enExample)
WO (1) WO2015165966A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106535924A (zh) 2014-04-29 2017-03-22 阿费里斯股份公司 阿尔茨海默病(ad)的治疗和预防
KR102506460B1 (ko) * 2014-04-29 2023-03-03 어드밴티지 테라퓨틱스, 인코포레이티드 알츠하이머병（ａｄ）의 치료 및 예방

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994016327A1 (en) * 1993-01-14 1994-07-21 Pollard Harvey B Methods and compositions for blocking amyloid protein ion channels
EP1007040B1 (en) * 1997-08-21 2002-05-08 P.N. Gerolymatos S.A. Use of phanquinone for the treatment of alzheimer's disease
TWI239847B (en) * 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
CN104436212A (zh) * 2010-03-29 2015-03-25 诺华股份有限公司 包含与病毒样颗粒偶联的淀粉样β1-6肽及佐剂的组合物
CN106535924A (zh) * 2014-04-29 2017-03-22 阿费里斯股份公司 阿尔茨海默病(ad)的治疗和预防
KR102506460B1 (ko) * 2014-04-29 2023-03-03 어드밴티지 테라퓨틱스, 인코포레이티드 알츠하이머병（ａｄ）의 치료 및 예방

Also Published As

Publication number Publication date
EP3269376A1 (en) 2018-01-17
ES2824763T3 (es) 2021-05-13
AU2015254663A1 (en) 2016-11-10
CN106659738B (zh) 2021-02-09
HRP20171896T1 (hr) 2018-02-23
PL3137093T3 (pl) 2018-06-29
CA2946928A1 (en) 2015-11-05
KR20160145822A (ko) 2016-12-20
ES2651537T3 (es) 2018-01-29
KR102388363B1 (ko) 2022-04-19
DK3137093T3 (en) 2017-12-11
AU2015254663B2 (en) 2020-04-02
CN106659738A (zh) 2017-05-10
SI3137093T1 (en) 2018-01-31
PT3137093T (pt) 2017-12-19
EP3137093B1 (en) 2017-09-13
HUE037501T2 (hu) 2018-08-28
EP3137093A1 (en) 2017-03-08
CY1119674T1 (el) 2018-04-04
JP2017518275A (ja) 2017-07-06
JP6692755B2 (ja) 2020-05-13
LT3137093T (lt) 2017-12-11
WO2015165966A1 (en) 2015-11-05
EP3269376B1 (en) 2020-07-15
NO3137093T3 (enExample) 2018-02-10
US20170049812A1 (en) 2017-02-23
US10478454B2 (en) 2019-11-19

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Legal Events

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EEER Examination request

Effective date: 20200429

EEER Examination request

Effective date: 20200429

EEER Examination request

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EEER Examination request

Effective date: 20200429