CA2946119A1 - Carbohydrate-binding protein - Google Patents

Carbohydrate-binding protein Download PDF

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Publication number
CA2946119A1
CA2946119A1 CA2946119A CA2946119A CA2946119A1 CA 2946119 A1 CA2946119 A1 CA 2946119A1 CA 2946119 A CA2946119 A CA 2946119A CA 2946119 A CA2946119 A CA 2946119A CA 2946119 A1 CA2946119 A1 CA 2946119A1
Authority
CA
Canada
Prior art keywords
pngase
protein
binding
glycan
catalytically inactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2946119A
Other languages
English (en)
French (fr)
Inventor
Kausar N. Samli
Robert J. Woods
Loretta Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Georgia Research Foundation Inc
GLYCOSENSORS AND DIAGNOSTICS LLC
Original Assignee
University of Georgia Research Foundation Inc
GLYCOSENSORS AND DIAGNOSTICS LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Georgia Research Foundation Inc, GLYCOSENSORS AND DIAGNOSTICS LLC filed Critical University of Georgia Research Foundation Inc
Publication of CA2946119A1 publication Critical patent/CA2946119A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01052—Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (3.5.1.52), i.e. glycopeptidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2946119A 2014-04-18 2015-04-17 Carbohydrate-binding protein Pending CA2946119A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461981335P 2014-04-18 2014-04-18
US61/981,335 2014-04-18
PCT/US2015/026374 WO2015161201A1 (en) 2014-04-18 2015-04-17 Carbohydrate-binding protein

Publications (1)

Publication Number Publication Date
CA2946119A1 true CA2946119A1 (en) 2015-10-22

Family

ID=54324612

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2946119A Pending CA2946119A1 (en) 2014-04-18 2015-04-17 Carbohydrate-binding protein

Country Status (7)

Country Link
US (2) US10358637B2 (https=)
EP (1) EP3132031B1 (https=)
JP (1) JP6814043B2 (https=)
CA (1) CA2946119A1 (https=)
DK (1) DK3132031T3 (https=)
IL (1) IL248276B (https=)
WO (1) WO2015161201A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3132031B1 (en) 2014-04-18 2020-10-21 University of Georgia Research Foundation, Inc. Carbohydrate-binding protein
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent
AU2018258251B2 (en) 2017-04-24 2024-06-20 Glycosensors And Diagnostics, Llc Sialic acid binding polypeptide
US11262309B2 (en) * 2018-07-11 2022-03-01 Advanced Cytometry Instrumentation Systems, Llc Methods for lipid measurement in cells
KR20220043213A (ko) * 2019-08-12 2022-04-05 메타웨이브 코포레이션 빔 형성 시스템을 위한 메타 구조의 무선 인프라구조
WO2023287511A2 (en) * 2021-06-02 2023-01-19 Board Of Regents, The University Of Texas System Methods and compositions related to engineered biosensors
CN120060392A (zh) * 2025-02-26 2025-05-30 武汉糖智药业有限公司 一种n-糖肽制备n-糖氨基酸的方法及n-糖氨基酸

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935804A (en) 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
TW496775B (en) 1999-03-15 2002-08-01 Aviva Bioscience Corp Individually addressable micro-electromagnetic unit array chips
US6376210B1 (en) 1999-07-06 2002-04-23 General Atomics Methods and compositions for assaying analytes
US6780627B1 (en) 2000-01-31 2004-08-24 Millennium Pharmaceuticals, Inc. 22438, 23553, 25278, and 26212 novel human sulfatases
US20060141480A1 (en) 1999-11-10 2006-06-29 Kalyanaraman Ramnarayan Use of computationally derived protein structures of genetic polymorphisms in pharmacogenomics and clinical applications
JP2005510229A (ja) * 2001-11-28 2005-04-21 ネオーズ テクノロジーズ， インコーポレイテッド アミダーゼを用いる糖タンパク質のリモデリング
US20060040327A1 (en) 2004-08-18 2006-02-23 Terry Amiss Methods of screening proteins
US20060172339A1 (en) 2004-11-29 2006-08-03 Perkinelmer Las, Inc. Particle-based multiplex assay for identifying glycosylation
US9201010B2 (en) 2008-05-01 2015-12-01 The United States Of America, As Represented By The Secretary Of The Navy Fluorescent organic nanoparticles
JP5986745B2 (ja) 2008-07-15 2016-09-06 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ Ｐｔｆｅ様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法
EP2367562B1 (en) 2008-12-10 2019-11-20 University Of Georgia Research Foundation, Inc. Glycan-specific analytical tools
WO2012118928A2 (en) 2011-03-01 2012-09-07 University Of Georgia Research Foundation, Inc. Glycoprofiling with multiplexed suspension arrays
CA2839932C (en) * 2011-06-07 2022-07-05 Ibio, Inc. In vivo de-glycosylation of recombinant proteins by co-expression with pngase f
EP3132031B1 (en) 2014-04-18 2020-10-21 University of Georgia Research Foundation, Inc. Carbohydrate-binding protein
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent

Also Published As

Publication number Publication date
EP3132031A1 (en) 2017-02-22
JP6814043B2 (ja) 2021-01-13
JP2017513488A (ja) 2017-06-01
WO2015161201A1 (en) 2015-10-22
EP3132031A4 (en) 2017-10-18
US11001824B1 (en) 2021-05-11
EP3132031B1 (en) 2020-10-21
IL248276A0 (en) 2016-11-30
DK3132031T3 (da) 2021-01-11
IL248276B (en) 2021-01-31
US10358637B2 (en) 2019-07-23
US20170191049A1 (en) 2017-07-06
WO2015161201A8 (en) 2016-01-07

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