CA2936458C - Implantable sensor and method for such sensor - Google Patents
Implantable sensor and method for such sensor Download PDFInfo
- Publication number
- CA2936458C CA2936458C CA2936458A CA2936458A CA2936458C CA 2936458 C CA2936458 C CA 2936458C CA 2936458 A CA2936458 A CA 2936458A CA 2936458 A CA2936458 A CA 2936458A CA 2936458 C CA2936458 C CA 2936458C
- Authority
- CA
- Canada
- Prior art keywords
- pair
- impedance
- khz
- detector
- electrodes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title claims description 52
- 238000002347 injection Methods 0.000 claims abstract description 60
- 239000007924 injection Substances 0.000 claims abstract description 60
- 210000001519 tissue Anatomy 0.000 claims abstract description 59
- 238000004891 communication Methods 0.000 claims abstract description 49
- 230000005672 electromagnetic field Effects 0.000 claims abstract description 15
- 206010033675 panniculitis Diseases 0.000 claims abstract description 7
- 210000004304 subcutaneous tissue Anatomy 0.000 claims abstract description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 50
- 239000008103 glucose Substances 0.000 claims description 50
- 238000012544 monitoring process Methods 0.000 claims description 34
- 239000008280 blood Substances 0.000 claims description 20
- 210000004369 blood Anatomy 0.000 claims description 20
- 230000003287 optical effect Effects 0.000 claims description 11
- 238000002847 impedance measurement Methods 0.000 claims description 9
- 238000000605 extraction Methods 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 6
- 210000000056 organ Anatomy 0.000 description 26
- 230000015654 memory Effects 0.000 description 16
- 230000036571 hydration Effects 0.000 description 14
- 238000006703 hydration reaction Methods 0.000 description 14
- 238000002513 implantation Methods 0.000 description 12
- 230000008859 change Effects 0.000 description 11
- 238000005259 measurement Methods 0.000 description 10
- 239000003814 drug Substances 0.000 description 9
- 208000028867 ischemia Diseases 0.000 description 9
- 239000000523 sample Substances 0.000 description 9
- 238000002054 transplantation Methods 0.000 description 9
- 206010012601 diabetes mellitus Diseases 0.000 description 8
- 229940079593 drug Drugs 0.000 description 8
- 230000003862 health status Effects 0.000 description 8
- 238000012545 processing Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 208000015181 infectious disease Diseases 0.000 description 7
- 230000008878 coupling Effects 0.000 description 6
- 238000010168 coupling process Methods 0.000 description 6
- 238000005859 coupling reaction Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 230000001939 inductive effect Effects 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 230000036626 alertness Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000002611 ovarian Effects 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 230000036760 body temperature Effects 0.000 description 4
- 230000035558 fertility Effects 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 230000002727 hyperosmolar Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 3
- 241001494479 Pecora Species 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 206010037423 Pulmonary oedema Diseases 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000003748 differential diagnosis Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 230000003907 kidney function Effects 0.000 description 2
- 239000004973 liquid crystal related substance Substances 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 238000011068 loading method Methods 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000006855 networking Effects 0.000 description 2
- 230000016087 ovulation Effects 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 208000005333 pulmonary edema Diseases 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000010183 spectrum analysis Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010048962 Brain oedema Diseases 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 241000766026 Coregonus nasus Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000008445 altitude sickness Diseases 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000002715 bioenergetic effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 208000006752 brain edema Diseases 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 210000003976 gap junction Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000001566 impedance spectroscopy Methods 0.000 description 1
- 238000001453 impedance spectrum Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000013535 sea water Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0012—Ovulation-period determination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0538—Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/076—Permanent implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7228—Signal modulation applied to the input signal sent to patient or subject; Demodulation to recover the physiological signal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0012—Ovulation-period determination
- A61B2010/0016—Ovulation-period determination based on measurement of electric currents, e.g. conductivity tests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/20—Workers
- A61B2503/22—Motor vehicles operators, e.g. drivers, pilots, captains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0204—Operational features of power management
- A61B2560/0214—Operational features of power management of power generation or supply
- A61B2560/0219—Operational features of power management of power generation or supply of externally powered implanted units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
- A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0537—Measuring body composition by impedance, e.g. tissue hydration or fat content
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/413—Monitoring transplanted tissue or organ, e.g. for possible rejection reactions after a transplant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4318—Evaluation of the lower reproductive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4869—Determining body composition
- A61B5/4875—Hydration status, fluid retention of the body
- A61B5/4878—Evaluating oedema
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Signal Processing (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Artificial Intelligence (AREA)
- Emergency Medicine (AREA)
- Optics & Photonics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Power Engineering (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/157,298 | 2014-01-16 | ||
| US14/157,298 US20150196224A1 (en) | 2014-01-16 | 2014-01-16 | Implantable Sensor and Method for Such Sensor |
| PCT/EP2015/050484 WO2015107040A1 (en) | 2014-01-16 | 2015-01-13 | Implantable sensor and method for such sensor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2936458A1 CA2936458A1 (en) | 2015-07-23 |
| CA2936458C true CA2936458C (en) | 2023-06-20 |
Family
ID=52347328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2936458A Active CA2936458C (en) | 2014-01-16 | 2015-01-13 | Implantable sensor and method for such sensor |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20150196224A1 (OSRAM) |
| EP (1) | EP3094246B1 (OSRAM) |
| JP (1) | JP6549154B2 (OSRAM) |
| KR (1) | KR102367129B1 (OSRAM) |
| CN (1) | CN106028926A (OSRAM) |
| AU (1) | AU2015206084B2 (OSRAM) |
| BR (1) | BR112016016451B1 (OSRAM) |
| CA (1) | CA2936458C (OSRAM) |
| ES (1) | ES2973033T3 (OSRAM) |
| MX (1) | MX2016008954A (OSRAM) |
| WO (1) | WO2015107040A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9597111B2 (en) | 2010-08-06 | 2017-03-21 | Kci Licensing, Inc. | Methods for applying a skin graft |
| CA2982203C (en) | 2015-04-09 | 2021-05-11 | Kci Licensing, Inc. | Soft-tack, porous substrates for harvesting skin grafts |
| EP3370630B1 (en) | 2015-11-03 | 2021-06-16 | 3M Innovative Properties Company | Device for creating an epidermal graft sheet |
| KR101902078B1 (ko) * | 2016-12-13 | 2018-09-27 | (재)대구포교성베네딕도수녀회 | ATP(Adenosine TriPhosphate) 기반 혈당계 |
| KR101751879B1 (ko) * | 2016-12-15 | 2017-06-29 | 주식회사 헬스리안 | 접촉 강도에 따른 인체 매질 통신 최적화 구현 통신장치 |
| KR101925632B1 (ko) | 2017-01-26 | 2018-12-05 | 울산과학기술원 | 체내 이식형 혈당 측정 장치 및 방법 |
| CN110325103A (zh) * | 2017-01-31 | 2019-10-11 | Giomi创新与研究有限公司 | 用于假体监测的可植入设备 |
| EP3651670A1 (en) * | 2017-07-12 | 2020-05-20 | KCI Licensing, Inc. | Ac impedance sensor systems for skin graft harvesting |
| KR20190043237A (ko) | 2017-10-18 | 2019-04-26 | 한국 한의학 연구원 | 건강정보 획득 장치 및 방법 |
| KR101974284B1 (ko) * | 2017-10-24 | 2019-04-30 | 울산과학기술원 | 혈당 측정 장치 및 방법 |
| CN113543704B (zh) * | 2018-10-26 | 2024-06-04 | 心脏起搏器股份公司 | 多传感器糖尿病管理系统 |
| FR3091989B1 (fr) * | 2019-01-24 | 2022-12-16 | Sentinhealth | Dispositif de mesure de bio-impedance du tractus digestif |
| KR102532761B1 (ko) * | 2019-08-02 | 2023-05-16 | 바이오나임 코포레이션 | 마이크로 바이오센서의 측정 간섭 감소 방법 |
| CN112294307B (zh) * | 2019-08-02 | 2024-08-20 | 华广生技股份有限公司 | 生理信号传感装置 |
| CN119745450A (zh) * | 2019-11-11 | 2025-04-04 | 新加坡国立大学 | 无线触发装置 |
| CN114761070A (zh) * | 2019-11-11 | 2022-07-15 | 卡里扬科技有限公司 | 用于监测治疗和/或提供治疗的皮下装置 |
| US12457013B2 (en) * | 2019-11-27 | 2025-10-28 | National University Of Singapore | Methods and systems for near-field communication |
| KR102379568B1 (ko) * | 2020-04-23 | 2022-03-28 | 울산과학기술원 | 바이오 인피던스 계측용 시스템 |
| EP4042941B1 (en) * | 2021-02-11 | 2024-08-07 | D.T.R. Dermal Therapy Research Inc. | Implantable glucose sensor |
| EP4257037A1 (en) * | 2022-04-05 | 2023-10-11 | D.T.R. Dermal Therapy Research Inc. | Implantable sensor with optimal electrode distance |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0955871A4 (en) * | 1995-04-20 | 2000-03-22 | Microcor Inc | METHOD AND APPARATUS FOR NON-INVASIVE DETERMINATION OF HEMATOCRITIS |
| DE19638585A1 (de) * | 1996-09-20 | 1998-03-26 | Biotronik Mess & Therapieg | Vorrichtung zur Rejektionsdiagnostik nach Organtransplantationen |
| US6088608A (en) * | 1997-10-20 | 2000-07-11 | Alfred E. Mann Foundation | Electrochemical sensor and integrity tests therefor |
| US6198965B1 (en) * | 1997-12-30 | 2001-03-06 | Remon Medical Technologies, Ltd. | Acoustic telemetry system and method for monitoring a rejection reaction of a transplanted organ |
| US6970741B1 (en) * | 2001-09-18 | 2005-11-29 | Advanced Bionics Corporation | Monitoring, preventing, and treating rejection of transplanted organs |
| US8777851B2 (en) * | 2001-10-01 | 2014-07-15 | Medtronic, Inc. | Congestive heart failure monitor and ventilation measuring implant |
| US7306603B2 (en) * | 2002-08-21 | 2007-12-11 | Innovative Spinal Technologies | Device and method for percutaneous placement of lumbar pedicle screws and connecting rods |
| WO2004034032A2 (en) | 2002-10-11 | 2004-04-22 | Case Western Reserve University | Sliver type autonomous biosensors |
| US7041096B2 (en) * | 2002-10-24 | 2006-05-09 | Synergetics Usa, Inc. | Electrosurgical generator apparatus |
| US7130679B2 (en) * | 2002-11-20 | 2006-10-31 | Medtronic, Inc. | Organ rejection monitoring |
| PL1718200T3 (pl) * | 2004-02-05 | 2017-01-31 | Dermal Devices Inc. | Urządzenie do mierzenia glukozy we krwi z użyciem pomiarów impedancji sub-skórnej tkanki ciała |
| JP4977020B2 (ja) | 2004-07-08 | 2012-07-18 | シェンバーガー，デボラ | 歪モニタリングシステム及び装置 |
| CN101194836B (zh) * | 2006-12-05 | 2011-09-14 | 重庆博恩富克医疗设备有限公司 | 一种生物电阻抗测量中消除干扰的方法和装置 |
| ES2543967T3 (es) * | 2007-01-15 | 2015-08-26 | Impedimed Limited | Método para efectuar mediciones de impedancia en un sujeto |
| WO2009121392A1 (en) * | 2008-03-31 | 2009-10-08 | Scibase Ab | Method and device for non-invasive determination of the concentration of a substance in a body fluid |
| TWI424832B (zh) * | 2008-12-15 | 2014-02-01 | Proteus Digital Health Inc | 與身體有關的接收器及其方法 |
| US11169010B2 (en) * | 2009-07-27 | 2021-11-09 | Integra Lifesciences Switzerland Sàrl | Method for the calibration of an implantable sensor |
| CN102499678B (zh) * | 2011-09-23 | 2013-11-06 | 中国人民解放军第四军医大学 | 一种便携式电阻抗成像系统的电阻抗测量装置及测量方法 |
-
2014
- 2014-01-16 US US14/157,298 patent/US20150196224A1/en not_active Abandoned
-
2015
- 2015-01-13 MX MX2016008954A patent/MX2016008954A/es active IP Right Grant
- 2015-01-13 ES ES15700296T patent/ES2973033T3/es active Active
- 2015-01-13 KR KR1020167022352A patent/KR102367129B1/ko active Active
- 2015-01-13 WO PCT/EP2015/050484 patent/WO2015107040A1/en not_active Ceased
- 2015-01-13 CN CN201580004881.7A patent/CN106028926A/zh active Pending
- 2015-01-13 AU AU2015206084A patent/AU2015206084B2/en active Active
- 2015-01-13 EP EP15700296.5A patent/EP3094246B1/en active Active
- 2015-01-13 JP JP2016564391A patent/JP6549154B2/ja active Active
- 2015-01-13 BR BR112016016451-2A patent/BR112016016451B1/pt active IP Right Grant
- 2015-01-13 CA CA2936458A patent/CA2936458C/en active Active
-
2019
- 2019-05-06 US US16/404,423 patent/US20190254559A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016016451A2 (OSRAM) | 2017-08-08 |
| WO2015107040A1 (en) | 2015-07-23 |
| CA2936458A1 (en) | 2015-07-23 |
| JP6549154B2 (ja) | 2019-07-24 |
| CN106028926A (zh) | 2016-10-12 |
| EP3094246A1 (en) | 2016-11-23 |
| KR102367129B1 (ko) | 2022-02-25 |
| KR20160108531A (ko) | 2016-09-19 |
| AU2015206084B2 (en) | 2018-11-08 |
| US20150196224A1 (en) | 2015-07-16 |
| EP3094246C0 (en) | 2024-03-06 |
| AU2015206084A1 (en) | 2016-07-21 |
| BR112016016451B1 (pt) | 2022-10-25 |
| MX2016008954A (es) | 2017-02-02 |
| ES2973033T3 (es) | 2024-06-18 |
| EP3094246B1 (en) | 2024-03-06 |
| US20190254559A1 (en) | 2019-08-22 |
| JP2017506995A (ja) | 2017-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2936458C (en) | Implantable sensor and method for such sensor | |
| CA2936487C (en) | Health monitoring system | |
| US10512723B1 (en) | Control of a peripheral device with a bandage-type analyte sensor | |
| US10478101B1 (en) | Continuous glucose monitoring based on remote sensing of variations of parameters of a SiC implanted antenna | |
| US20190374138A1 (en) | Kit for determining an analyte concentration | |
| US20160310048A1 (en) | Implantable Biosensor | |
| ES2813676T3 (es) | Sistema de monitorización continua de glucosa y terminal de monitorización | |
| US11835479B2 (en) | Systems, devices, and methods for RF detection of analyte sensor measurements | |
| CN114746016A (zh) | 用于减少计算的和测量的分析物水平之间差异的方法和系统 | |
| EP4456788B1 (en) | A wearable device for continuous monitoring of health parameters | |
| US12016684B2 (en) | Environmental detection and/or temperature compensation in an analyte monitoring system | |
| US12478297B2 (en) | Methods and systems for reducing difference between calculated and measured analyte levels | |
| EP4335368A1 (en) | Methods and systems for reducing difference between calculated and measured analyte levels | |
| Riz | Development and assessment of linear regression techniques for modeling multisensor data for non-invasive continuos glucose monitoring |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20200113 |
|
| EEER | Examination request |
Effective date: 20200113 |
|
| EEER | Examination request |
Effective date: 20200113 |
|
| EEER | Examination request |
Effective date: 20200113 |
|
| EEER | Examination request |
Effective date: 20200113 |
|
| EEER | Examination request |
Effective date: 20200113 |
|
| EEER | Examination request |
Effective date: 20200113 |