CA2933819C - Nouveau site de fixation de la trh dans le snc chez l'homme - Google Patents

Nouveau site de fixation de la trh dans le snc chez l'homme

Info

Publication number
CA2933819C
CA2933819C CA2933819A CA2933819A CA2933819C CA 2933819 C CA2933819 C CA 2933819C CA 2933819 A CA2933819 A CA 2933819A CA 2933819 A CA2933819 A CA 2933819A CA 2933819 C CA2933819 C CA 2933819C
Authority
CA
Canada
Prior art keywords
pro
asn
trh
glp
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2933819A
Other languages
English (en)
Other versions
CA2933819A1 (fr
Inventor
Julie Kelly
Original Assignee
College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IE20120542A external-priority patent/IE20120542A1/en
Application filed by College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin filed Critical College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
Publication of CA2933819A1 publication Critical patent/CA2933819A1/fr
Application granted granted Critical
Publication of CA2933819C publication Critical patent/CA2933819C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L'invention concerne un nouveau sous-type de récepteurs de la thyrolibérine (TRH) du système nerveux central (SNC) chez l'homme, qui est pharmacologiquement distinct du sous-type de récepteurs de la TRH de l'hypophyse. L'invention permet de comprendre comment les actions centrales de la TRH sont relayées et d'isoler et de caractériser le nouveau récepteur. Ll'invention concerne également des méthodes applicables à la recherche et au développement d'applications diagnostiques et thérapeutiques dans les troubles du SNC chez l'homme.
CA2933819A 2012-12-19 2013-12-18 Nouveau site de fixation de la trh dans le snc chez l'homme Active CA2933819C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IE20120542A IE20120542A1 (en) 2012-12-19 2012-12-19 Novel TRH binding site in human CNS
IE2012/0542 2012-12-19
PCT/EP2013/077221 WO2014096090A1 (fr) 2012-12-19 2013-12-18 Nouveau site de fixation de la trh dans le snc chez l'homme

Publications (2)

Publication Number Publication Date
CA2933819A1 CA2933819A1 (fr) 2014-06-26
CA2933819C true CA2933819C (fr) 2025-09-09

Family

ID=

Similar Documents

Publication Publication Date Title
Kolakowski et al. Characterization of a human gene related to genes encoding somatostatin receptors
Blein et al. The metabotropic GABA receptor: molecular insights and their functional consequences
AU2013360758B2 (en) Novel TRH binding site in human CNS
EP0612845A2 (fr) Récepteur d'opioides purifié
CA2933819C (fr) Nouveau site de fixation de la trh dans le snc chez l'homme
CA2931005C (fr) Agents ciblant le cartilage et leur utilisation
CA3025515C (fr) Systemes et procedes de gestion de sequence de taches et de pratique
AU4209500A (en) DNA encoding orphan receptors
EP1311677B1 (fr) Regulation du recepteur couple a la proteine g humaine du type p2y1
NZ710107B2 (en) Novel trh binding site in human cns
JP2016509200A6 (ja) ヒトｃｎｓにおける新規ｔｒｈ結合部位
Miotto et al. Molecular characterization of opioid receptors
Ioja et al. Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles
WO1995012616A1 (fr) Molecules d'acide nucleique codant des recepteurs d'opioides kappa3, recepteurs d'opioides codes par lesdites molecules et utilisation
JPWO2003027672A1 (ja) プロキネティシン受容体を用いた新規スクリーニング方法
US20020099200A1 (en) Dna encoding orphan snorf66 receptor
US20020077469A1 (en) DNA encoding orphan SNORF11 receptor
US20030022839A1 (en) Receptor agonists useful for the treatment of pain
Tóth et al. Synthesis and binding characteristics of [3H] neuromedin N, a NTS2 receptor ligand
US20020151705A1 (en) DNA encoding orphan SNORF49 receptor
Lamey Identification of distinct residues in the carboxyl tail regulating desensitization and internalization of the D¦ 1 dopamine receptor
US20020161217A1 (en) DNA encoding orphan SNORF40 receptor
US20030143670A1 (en) DNA encoding SNORF44 receptor
US20030104534A1 (en) DNA encoding orphan SNORF42 receptor
US20020161216A1 (en) DNA encoding orphan SNORF4 receptor