CA2932266A1 - Methods for treating hematological cancers and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies - Google Patents
Methods for treating hematological cancers and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies Download PDFInfo
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- CA2932266A1 CA2932266A1 CA2932266A CA2932266A CA2932266A1 CA 2932266 A1 CA2932266 A1 CA 2932266A1 CA 2932266 A CA2932266 A CA 2932266A CA 2932266 A CA2932266 A CA 2932266A CA 2932266 A1 CA2932266 A1 CA 2932266A1
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201361913046P | 2013-12-06 | 2013-12-06 | |
| US61/913,046 | 2013-12-06 | ||
| PCT/US2014/068767 WO2015085160A2 (en) | 2013-12-06 | 2014-12-05 | Methods for treating hematological cancers and the use of biomarkers as a predictor of clinical sensitivity to immunodulatory therapies |
Publications (1)
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| CA2932266A1 true CA2932266A1 (en) | 2015-06-11 |
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| CA2932266A Abandoned CA2932266A1 (en) | 2013-12-06 | 2014-12-05 | Methods for treating hematological cancers and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
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| US (1) | US20160312292A1 (OSRAM) |
| EP (1) | EP3077547A4 (OSRAM) |
| JP (1) | JP2017503481A (OSRAM) |
| KR (1) | KR20160090390A (OSRAM) |
| AU (1) | AU2014360316A1 (OSRAM) |
| BR (1) | BR112016012792A2 (OSRAM) |
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| EA (1) | EA201691143A1 (OSRAM) |
| IL (1) | IL245936A0 (OSRAM) |
| MX (1) | MX2016007179A (OSRAM) |
| PH (1) | PH12016501023A1 (OSRAM) |
| WO (1) | WO2015085160A2 (OSRAM) |
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| US20160282354A1 (en) | 2013-11-08 | 2016-09-29 | The Broad Institute, Inc. | Compositions and methods for selecting a treatment for b-cell neoplasias |
| AU2014360328B2 (en) | 2013-12-06 | 2021-04-01 | Celgene Corporation | Methods for determining drug efficacy for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancers |
| US10311571B2 (en) * | 2014-10-17 | 2019-06-04 | Stichting Maastricht Radiation Oncology “Maastro-Clinic” | Image analysis method supporting illness development prediction for a neoplasm in a human or animal body |
| EP3304076A4 (en) | 2015-06-02 | 2018-12-19 | Celgene Corporation | Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins |
| EP3347717A4 (en) | 2015-09-11 | 2019-06-05 | The Brigham and Women's Hospital, Inc. | PROCESS FOR CHARACTERIZING THE RESISTANCE TO CEREBLON MODULATORS |
| KR20180052747A (ko) * | 2015-09-25 | 2018-05-18 | 셀진 코포레이션 | 미만성 거대 b세포 림프종의 치료 방법 및 약물에 대한 반응성의 예측자로서 바이오마커의 용도 |
| CA3010801A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
| US20200270703A1 (en) * | 2017-09-29 | 2020-08-27 | Kyushu University, National University Corporation | Method and kit for predicting therapeutic effectiveness of chemotherapy for diffuse large b-cell lymphoma patients |
| CN115175903A (zh) * | 2019-10-21 | 2022-10-11 | 新基公司 | 治疗血液癌症的方法和2-(2,6-二氧代哌啶-3-基)-4-((2-氟-4-((3-吗啉代氮杂环丁烷-1-基)甲基)苄基)氨基)异吲哚啉-1,3-二酮伴随生物标志物的用途 |
| WO2024258819A1 (en) * | 2023-06-15 | 2024-12-19 | The Broad Institute, Inc. | Neoplastic cytotoxicity induced by glycosylation |
| FR3158742A1 (fr) * | 2024-01-30 | 2025-08-01 | Universite Grenoble Alpes | Biomarqueurs et outil pronostique pour les patients atteint de lymphomes b diffus a grandes cellules |
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| CA2710196A1 (en) * | 2007-12-20 | 2009-07-09 | Celgene Corporation | Use of micro-rna as a biomarker of immunomodulatory drug activity |
| MX2012010367A (es) * | 2010-03-12 | 2012-11-23 | Celgene Corp | Metodos para el tratamiento de linfomas no hodgkin que usan lenalidomida y biomarcadores de genes y proteinas como un predictor. |
| US9365640B2 (en) * | 2011-04-29 | 2016-06-14 | Celgene Corporation | Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor |
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2014
- 2014-12-05 EA EA201691143A patent/EA201691143A1/ru unknown
- 2014-12-05 US US15/101,866 patent/US20160312292A1/en not_active Abandoned
- 2014-12-05 BR BR112016012792A patent/BR112016012792A2/pt not_active Application Discontinuation
- 2014-12-05 WO PCT/US2014/068767 patent/WO2015085160A2/en not_active Ceased
- 2014-12-05 AU AU2014360316A patent/AU2014360316A1/en not_active Abandoned
- 2014-12-05 KR KR1020167017539A patent/KR20160090390A/ko not_active Withdrawn
- 2014-12-05 JP JP2016536527A patent/JP2017503481A/ja active Pending
- 2014-12-05 CA CA2932266A patent/CA2932266A1/en not_active Abandoned
- 2014-12-05 MX MX2016007179A patent/MX2016007179A/es unknown
- 2014-12-05 EP EP14867978.0A patent/EP3077547A4/en not_active Withdrawn
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2016
- 2016-05-31 IL IL245936A patent/IL245936A0/en unknown
- 2016-05-31 PH PH12016501023A patent/PH12016501023A1/en unknown
Also Published As
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| MX2016007179A (es) | 2016-09-08 |
| EP3077547A2 (en) | 2016-10-12 |
| AU2014360316A1 (en) | 2016-06-16 |
| WO2015085160A3 (en) | 2015-07-30 |
| JP2017503481A (ja) | 2017-02-02 |
| KR20160090390A (ko) | 2016-07-29 |
| EA201691143A1 (ru) | 2016-11-30 |
| PH12016501023A1 (en) | 2016-07-04 |
| IL245936A0 (en) | 2016-07-31 |
| WO2015085160A2 (en) | 2015-06-11 |
| BR112016012792A2 (pt) | 2017-08-08 |
| EP3077547A4 (en) | 2017-11-08 |
| US20160312292A1 (en) | 2016-10-27 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20191205 |