CA2926888C - Modulation of the physical interaction between platelets and the cell surface effecting cell proliferation - Google Patents
Modulation of the physical interaction between platelets and the cell surface effecting cell proliferation Download PDFInfo
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- CA2926888C CA2926888C CA2926888A CA2926888A CA2926888C CA 2926888 C CA2926888 C CA 2926888C CA 2926888 A CA2926888 A CA 2926888A CA 2926888 A CA2926888 A CA 2926888A CA 2926888 C CA2926888 C CA 2926888C
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- sulfated polysaccharide
- platelets
- glycosaminoglycan
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- heparin
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- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
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- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102013111630.2 | 2013-10-22 | ||
| DE102013111630 | 2013-10-22 | ||
| PCT/EP2014/072620 WO2015059177A1 (en) | 2013-10-22 | 2014-10-22 | Sulfated polysaccharides for use in the treatment of cancer |
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|---|---|
| CA2926888A1 CA2926888A1 (en) | 2015-04-30 |
| CA2926888C true CA2926888C (en) | 2020-03-24 |
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| CA2926888A Active CA2926888C (en) | 2013-10-22 | 2014-10-22 | Modulation of the physical interaction between platelets and the cell surface effecting cell proliferation |
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| EP (1) | EP3060223B1 (enExample) |
| JP (1) | JP6444399B2 (enExample) |
| AU (1) | AU2014339000B2 (enExample) |
| CA (1) | CA2926888C (enExample) |
| WO (1) | WO2015059177A1 (enExample) |
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| WO2016196256A2 (en) | 2015-06-04 | 2016-12-08 | University Of North Carolina At Greensboro | Non-aromatic difluoro analogues of resorcylic acid lactones |
| US11191743B2 (en) * | 2016-01-11 | 2021-12-07 | Dignity Health | Modulators of zinc activated cation channel |
| CA3072856A1 (en) | 2017-08-23 | 2019-02-28 | Cell Receptor AG | Combination of a mapk/erk pathway inhibitor and a glycosaminoglycan for the treatment of cancer |
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| US5262403A (en) * | 1986-03-10 | 1993-11-16 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II |
| US7781416B2 (en) * | 2000-01-25 | 2010-08-24 | Sigma-Tau Research Switzerland S.A. | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
| US20060154894A1 (en) * | 2004-09-15 | 2006-07-13 | Massachusetts Institute Of Technology | Biologically active surfaces and methods of their use |
| WO2010096466A2 (en) * | 2009-02-17 | 2010-08-26 | Novelmed Therapeutics, Inc. | Methods and compositions for inhibiting cellular proliferation and surgical adhesion |
| CN102917711A (zh) * | 2010-03-12 | 2013-02-06 | 澳大利亚国立大学 | 硫酸乙酰肝素替代疗法 |
| IT1401253B1 (it) * | 2010-04-23 | 2013-07-18 | Uni Degli Studi Carlo Bo Urbino | Uso del sulodexide per la riduzione delle metalloproteinasi di matrice. |
| TWI520740B (zh) * | 2011-02-02 | 2016-02-11 | 模範健康科技私人企業有限公司 | 利用多硫酸化多醣之骨髓水腫(水腫)的治療 |
| DK2861273T3 (da) * | 2012-06-13 | 2017-11-27 | Exthera Medical Corp | Anvendelse af heparin og kulhydrater til behandling af cancer. |
| EP3131534A4 (en) * | 2014-04-17 | 2017-12-20 | Memorial Sloan Kettering Cancer Center | Fucoidan nanogels and methods of their use and manufacture |
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2014
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- 2014-10-22 US US15/031,020 patent/US10098906B2/en active Active
- 2014-10-22 AU AU2014339000A patent/AU2014339000B2/en active Active
- 2014-10-22 EP EP14789548.6A patent/EP3060223B1/en active Active
- 2014-10-22 CA CA2926888A patent/CA2926888C/en active Active
- 2014-10-22 WO PCT/EP2014/072620 patent/WO2015059177A1/en not_active Ceased
Also Published As
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|---|---|
| EP3060223B1 (en) | 2017-08-30 |
| EP3060223A1 (en) | 2016-08-31 |
| JP2016534078A (ja) | 2016-11-04 |
| AU2014339000A1 (en) | 2016-04-28 |
| US20160367589A1 (en) | 2016-12-22 |
| WO2015059177A1 (en) | 2015-04-30 |
| JP6444399B2 (ja) | 2018-12-26 |
| AU2014339000B2 (en) | 2017-05-18 |
| CA2926888A1 (en) | 2015-04-30 |
| US10098906B2 (en) | 2018-10-16 |
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| Date | Code | Title | Description |
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Effective date: 20171121 |