CA2921864C - Virus d'arn exprimant il-12 destines a l'immunovirotherapie - Google Patents
Virus d'arn exprimant il-12 destines a l'immunovirotherapie Download PDFInfo
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- CA2921864C CA2921864C CA2921864A CA2921864A CA2921864C CA 2921864 C CA2921864 C CA 2921864C CA 2921864 A CA2921864 A CA 2921864A CA 2921864 A CA2921864 A CA 2921864A CA 2921864 C CA2921864 C CA 2921864C
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18441—Use of virus, viral particle or viral elements as a vector
- C12N2760/18443—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Abstract
La présente invention concerne un virus recombinant de la famille Paramyxoviridae comprenant au moins un polynucléotide exprimable codant un polypeptide IL-12, le polypeptide IL-12 étant un polypeptide de fusion IL-12 comprenant une sous-unité p35 dun IL-12 et une sous-unité p40 dun IL-12, à un polynucléotide le codant et une trousse le comprenant. De plus, la présente invention concerne une méthode pour traiter le cancer dun patient, la méthode comprenant létape de mettre le patient en contact avec un virus recombinant de la famille Paramyxoviridae de linvention pour traiter le cancer du patient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2921864A CA2921864C (fr) | 2016-02-25 | 2016-02-25 | Virus d'arn exprimant il-12 destines a l'immunovirotherapie |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2921864A CA2921864C (fr) | 2016-02-25 | 2016-02-25 | Virus d'arn exprimant il-12 destines a l'immunovirotherapie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2921864A1 CA2921864A1 (fr) | 2017-08-25 |
| CA2921864C true CA2921864C (fr) | 2021-08-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2921864A Active CA2921864C (fr) | 2016-02-25 | 2016-02-25 | Virus d'arn exprimant il-12 destines a l'immunovirotherapie |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2921864C (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112442504B (zh) * | 2020-12-10 | 2023-01-24 | 电子科技大学 | 一种重组草鱼白介素-12活性蛋白的制备方法 |
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Also Published As
| Publication number | Publication date |
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| CA2921864A1 (fr) | 2017-08-25 |
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