CA2905624C - Medical device intended for the long-term storage of a cornea, or for ex vivo experimentation on a human or animal cornea - Google Patents

Medical device intended for the long-term storage of a cornea, or for ex vivo experimentation on a human or animal cornea Download PDF

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Publication number
CA2905624C
CA2905624C CA2905624A CA2905624A CA2905624C CA 2905624 C CA2905624 C CA 2905624C CA 2905624 A CA2905624 A CA 2905624A CA 2905624 A CA2905624 A CA 2905624A CA 2905624 C CA2905624 C CA 2905624C
Authority
CA
Canada
Prior art keywords
cornea
endothelial
medical device
chamber
overpressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2905624A
Other languages
French (fr)
Other versions
CA2905624A1 (en
Inventor
Philippe Gain
Gilles Thuret
Sophie LAVERNE-ACQUART
Sebastien Soubaigne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Francais du Sang Ets
Universite Jean Monnet Saint Etienne
Ecole Nationale dIngenieurs de Saint Etienne ENISE
Original Assignee
Francais du Sang Ets
Universite Jean Monnet Saint Etienne
Ecole Nationale dIngenieurs de Saint Etienne ENISE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Francais du Sang Ets, Universite Jean Monnet Saint Etienne, Ecole Nationale dIngenieurs de Saint Etienne ENISE filed Critical Francais du Sang Ets
Publication of CA2905624A1 publication Critical patent/CA2905624A1/en
Application granted granted Critical
Publication of CA2905624C publication Critical patent/CA2905624C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation

Abstract

A medical device (1) for storing a corneal sample (3) comprises means for receiving and enclosing the corneal sample, secured to means for creating a pressure gradient with overpressure on the endothelial side and to means for circulating a storage liquid in arrangements provided in the means for receiving and enclosing. The means for receiving and enclosing sealingly enclose the scleral rim that surrounds the cornea to delimit separate endothelial and epithelial chambers in which storage medium can circulate with overpressure in the endothelial chamber. The intermediate part (2), and the endothelial cover (4), comprise inlet and outlet holes for storage medium to which there are connected the means for circulating the storage medium and the means for creating the pressure gradient between the endothelial chamber and the epithelial chamber with overpressure in the endothelial chamber. Preferably, the device comprises an epithelial cover (5) allowing adjustable applanation.
CA2905624A 2013-03-14 2013-03-14 Medical device intended for the long-term storage of a cornea, or for ex vivo experimentation on a human or animal cornea Active CA2905624C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/FR2013/050530 WO2014140434A1 (en) 2013-03-14 2013-03-14 Medical device intended for the long-term storage of a cornea, or for ex vivo experimentation on a human or animal cornea

Publications (2)

Publication Number Publication Date
CA2905624A1 CA2905624A1 (en) 2014-09-18
CA2905624C true CA2905624C (en) 2021-06-01

Family

ID=48128522

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2905624A Active CA2905624C (en) 2013-03-14 2013-03-14 Medical device intended for the long-term storage of a cornea, or for ex vivo experimentation on a human or animal cornea

Country Status (16)

Country Link
US (1) US10188097B2 (en)
EP (1) EP2991479B1 (en)
JP (1) JP6072316B2 (en)
CN (1) CN105188361B (en)
AU (1) AU2013382142B2 (en)
CA (1) CA2905624C (en)
DK (1) DK2991479T3 (en)
ES (1) ES2656062T3 (en)
HK (1) HK1215656A1 (en)
HR (1) HRP20180057T1 (en)
HU (1) HUE035349T2 (en)
IL (1) IL241486B (en)
NO (1) NO2991479T3 (en)
PL (1) PL2991479T3 (en)
PT (1) PT2991479T (en)
WO (1) WO2014140434A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20130713A1 (en) * 2013-12-23 2015-06-24 Roberta Foglia DEVICE FOR THE HANDLING AND TRANSPORT OF AN EYE BULB.
DE102014222547B3 (en) * 2014-11-05 2016-02-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Bioreactor system and method for long-term stabilization of corneal tissue
US10531560B2 (en) * 2016-03-31 2020-01-07 International Business Machines Corporation Use of conducting fluid in printed circuits
WO2017184667A1 (en) * 2016-04-19 2017-10-26 The United States Of America As Represented By The Secretary Of The Army Device and method for isolation of corneal endothelial cells
US10493455B2 (en) 2016-04-19 2019-12-03 The Government Of The United States, As Represented By The Secretary Of The Army Device and method for isolation of corneal endothelial cells
FR3061633B1 (en) 2017-01-09 2019-05-31 Universite De Franche Comte DEVICE AND METHOD FOR PRESERVING AND TRANSPORTING AT LEAST ONE HUMAN OR ANIMAL TISSUE FOR EX VIVO TRANSPLANT OR EXPERIENCE
FR3074997B1 (en) 2017-12-15 2019-11-08 Universite Jean Monnet CASSETTE MEDICAL DEVICE FOR PRESERVING AND / OR QUALITY CONTROL AND / OR TREATMENT OF CORNEAL SAMPLING
FR3074996B1 (en) * 2017-12-15 2019-11-08 Universite Jean Monnet MEDICAL DEVICE FOR PRESERVING AND / OR QUALITY CONTROL AND / OR TREATMENT OF CORNEAL SAMPLING INCLUDING AN APPLICATION COVER, AND IF NECESSARY A TREPANATION COVER
CN108100481B (en) * 2017-12-25 2023-10-31 青岛大学附属医院 Intelligent cornea preservation device
DE112018007802A5 (en) 2018-07-05 2021-04-15 Acto Service Gmbh Containers and methods for storing a corneal preparation
FR3083978B1 (en) * 2018-07-17 2023-12-08 Univ Jean Monnet Saint Etienne DEVICE FOR MAINTAINING CORNEAL TISSUE FOR PHOTONIC TREATMENT
US11154052B2 (en) 2018-09-14 2021-10-26 University Of Miami Dual-chamber vial for corneal graft preservation
CN113015429A (en) * 2018-10-02 2021-06-22 学校法人同志社 Method and container for preserving corneal endothelial cells
WO2020223211A1 (en) * 2019-04-30 2020-11-05 TECLens, LLC In vitro corneal crosslinking system for the preparation of transplantable tissue samples
FR3099045B1 (en) * 2019-07-22 2021-07-30 Univ Jean Monnet Saint Etienne PROCESS FOR PRODUCING A PLURALITY OF IMPLANTS FROM A HUMAN OR ANIMAL HORNA PREVIOUSLY TAKEN
JP6620905B1 (en) * 2019-08-29 2019-12-18 国立大学法人 長崎大学 Storage container
CN111919838A (en) * 2020-09-03 2020-11-13 林彩琴 Utilize fixed cell cryopreserving cooling box of atmospheric pressure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205747A (en) * 1978-09-05 1980-06-03 Cilco, Inc. Lens storage device
US5019084A (en) 1986-08-06 1991-05-28 Minnesota Mining And Manufacturing Company Corneal holder
US5030575A (en) * 1990-08-14 1991-07-09 Stofac Robert L Apparatus for preserving and testing living eye tissues
US5591636A (en) * 1993-10-18 1997-01-07 Precision Instrument Design Membrane holder
IL115390A (en) 1995-09-21 2001-07-24 Abdulrazik Mohammad Diffusion cell for ex-vivo pressure-controlled transcorneal drug penetration studies
ATE330631T1 (en) * 1999-01-05 2006-07-15 Univ Southern Australia ANTIBODIES FRAGMENTS FOR THE LOCAL TREATMENT OF EYE DISEASES
US7449307B2 (en) * 2002-10-28 2008-11-11 Transform Pharmaceuticals, Inc. Raised surface assay plate
US20080294149A1 (en) * 2007-05-25 2008-11-27 Arthur Krolman Corneal Viewing Chamber
FR2944185B1 (en) * 2009-04-09 2011-05-27 Peritesco INFUSION CHAMBER FOR CORNEA
FR2986133B1 (en) * 2012-01-30 2015-01-30 Univ Jean Monnet MEDICAL DEVICE FOR THE LONG-TERM CONSERVATION OF A HORN OR EX VIVO EXPERIMENTATION ON HUMAN OR ANIMAL HORN

Also Published As

Publication number Publication date
PL2991479T3 (en) 2018-04-30
HUE035349T2 (en) 2018-05-02
NO2991479T3 (en) 2018-03-17
WO2014140434A1 (en) 2014-09-18
AU2013382142A1 (en) 2015-10-01
DK2991479T3 (en) 2018-01-22
CN105188361A (en) 2015-12-23
AU2013382142B2 (en) 2016-12-22
PT2991479T (en) 2018-01-19
CA2905624A1 (en) 2014-09-18
CN105188361B (en) 2017-03-08
US10188097B2 (en) 2019-01-29
HK1215656A1 (en) 2016-09-09
US20160029618A1 (en) 2016-02-04
JP2016512492A (en) 2016-04-28
EP2991479A1 (en) 2016-03-09
EP2991479B1 (en) 2017-10-18
IL241486B (en) 2020-03-31
HRP20180057T1 (en) 2018-03-09
ES2656062T3 (en) 2018-02-23
JP6072316B2 (en) 2017-02-01
IL241486A0 (en) 2015-11-30

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Legal Events

Date Code Title Description
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Effective date: 20180112