CA2902728A1 - System and method for hazardous drug surface cleaning - Google Patents
System and method for hazardous drug surface cleaning Download PDFInfo
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- CA2902728A1 CA2902728A1 CA2902728A CA2902728A CA2902728A1 CA 2902728 A1 CA2902728 A1 CA 2902728A1 CA 2902728 A CA2902728 A CA 2902728A CA 2902728 A CA2902728 A CA 2902728A CA 2902728 A1 CA2902728 A1 CA 2902728A1
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- Prior art keywords
- solution
- cleaning
- hazardous drug
- isopropyl alcohol
- towelette
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- Abandoned
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- 231100001261 hazardous Toxicity 0.000 title claims abstract description 30
- 238000004140 cleaning Methods 0.000 title claims abstract description 29
- 238000000034 method Methods 0.000 title claims abstract description 13
- 229940079593 drug Drugs 0.000 title claims description 24
- 239000003814 drug Substances 0.000 title claims description 24
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims abstract description 48
- 229940126534 drug product Drugs 0.000 claims abstract description 17
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract description 17
- 125000001453 quaternary ammonium group Chemical group 0.000 claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 claims description 5
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 claims description 3
- 229930012538 Paclitaxel Natural products 0.000 claims description 3
- 229960004397 cyclophosphamide Drugs 0.000 claims description 3
- 229960002949 fluorouracil Drugs 0.000 claims description 3
- 229960001592 paclitaxel Drugs 0.000 claims description 3
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims description 3
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims description 2
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims description 2
- 229960004316 cisplatin Drugs 0.000 claims description 2
- 229960003668 docetaxel Drugs 0.000 claims description 2
- HOMGKSMUEGBAAB-UHFFFAOYSA-N ifosfamide Chemical compound ClCCNP1(=O)OCCCN1CCCl HOMGKSMUEGBAAB-UHFFFAOYSA-N 0.000 claims description 2
- 229960001101 ifosfamide Drugs 0.000 claims description 2
- 238000011109 contamination Methods 0.000 description 13
- 239000000463 material Substances 0.000 description 8
- 239000000047 product Substances 0.000 description 5
- 239000004744 fabric Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- -1 chemotherapy drugs Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- VVIAGPKUTFNRDU-UHFFFAOYSA-N 6S-folinic acid Natural products C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-UHFFFAOYSA-N 0.000 description 1
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 206010067125 Liver injury Diseases 0.000 description 1
- 208000005107 Premature Birth Diseases 0.000 description 1
- 206010036590 Premature baby Diseases 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229940044683 chemotherapy drug Drugs 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 231100000599 cytotoxic agent Toxicity 0.000 description 1
- 239000002619 cytotoxin Substances 0.000 description 1
- 238000007876 drug discovery Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- VVIAGPKUTFNRDU-ABLWVSNPSA-N folinic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-ABLWVSNPSA-N 0.000 description 1
- 235000008191 folinic acid Nutrition 0.000 description 1
- 239000011672 folinic acid Substances 0.000 description 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 description 1
- 229940020967 gemzar Drugs 0.000 description 1
- 239000002920 hazardous waste Substances 0.000 description 1
- 231100000206 health hazard Toxicity 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 229940022353 herceptin Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229960001691 leucovorin Drugs 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000012217 radiopharmaceutical Substances 0.000 description 1
- 229940121896 radiopharmaceutical Drugs 0.000 description 1
- 230000002799 radiopharmaceutical effect Effects 0.000 description 1
- 238000011012 sanitization Methods 0.000 description 1
- 231100000004 severe toxicity Toxicity 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/50—Solvents
- C11D7/5004—Organic solvents
- C11D7/5022—Organic solvents containing oxygen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
- C11D17/049—Cleaning or scouring pads; Wipes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/26—Organic compounds containing oxygen
- C11D7/261—Alcohols; Phenols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D2111/00—Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
- C11D2111/10—Objects to be cleaned
- C11D2111/14—Hard surfaces
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D2111/00—Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
- C11D2111/40—Specific cleaning or washing processes
- C11D2111/44—Multi-step processes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Detergent Compositions (AREA)
Abstract
The present invention relates to a method of cleaning a surface contaminated with a hazardous drug product involving cleaning in succession with a quaternary ammonium solution and an isopropyl alcohol solution.
Description
SYSTEM AND METHOD FOR HAZARDOUS DRUG SURFACE CLEANING
This application claims priority of US provisional application number 61/788,426 filed on March 15, 2013. All applications are incorporated in their entirety by reference.
COPYRIGHT NOTICE
A portion of the disclosure of this patent contains material that is subject to copyright protection. The copyright owner has no objection to the reproduction by anyone of the patent document or the patent disclosure as it appears in the Patent and Trademark Office patent files or records, but otherwise reserves all copyright rights whatsoever.
BACKGROUND OF THE INVENTION
Field of the Invention [001] The present invention relates to a method and system for cleaning surfaces.
More particularly the present invention relates to a method and system for the removal of hazardous drug products from surfaces.
Description of Related Art
This application claims priority of US provisional application number 61/788,426 filed on March 15, 2013. All applications are incorporated in their entirety by reference.
COPYRIGHT NOTICE
A portion of the disclosure of this patent contains material that is subject to copyright protection. The copyright owner has no objection to the reproduction by anyone of the patent document or the patent disclosure as it appears in the Patent and Trademark Office patent files or records, but otherwise reserves all copyright rights whatsoever.
BACKGROUND OF THE INVENTION
Field of the Invention [001] The present invention relates to a method and system for cleaning surfaces.
More particularly the present invention relates to a method and system for the removal of hazardous drug products from surfaces.
Description of Related Art
[002] The ability to clean environmental surfaces of contamination is an important job in many situations from food preparation to hazardous situations. Each situation has various particular issues for contamination removal and the systems for cleaning vary with the contamination to be removed.
[003] Most surface cleaning in work and other environments is to sanitize the area to remove viral and bacterial contamination under conditions where the contamination will harm the person using the environment or something prepared or worked on in the environment like food preparation or the like. Sanitization concentrates on killing the virus or bacteria and not on cleaning, though removal of the contamination is a form of cleaning. Dead bacterial left behind do not usually pose much, if any, of a threat. One of the most difficult areas of contamination is in areas where drugs and related hazardous drug products are utilized. In these situations the issue is not bacteria or virus killing, it is the complete removal of products that even minute quantities might cause severe toxicities, injury or even death to the subject or person exposed to the contamination.
[004] Since hazardous drugs are toxic, direct bodily contact thereto, or exposure to even micro-quantities of the drug, considerably increases the risk of developing health fatalities such as skin cancer, leukemia, liver damage, malformation, miscarriage and premature birth. Such exposure can take place when a drug containing receptacle, such as a vial, bottle, syringe, and intravenous bag, is subjected to overpressure, resulting in the leakage of fluid or air contaminated by the hazardous drug to the surroundings. Exposure to a hazardous drug also results from a drug solution remaining on a needle tip, on a vial or intravenous bag seal, or by the accidental puncturing of the skin by the needle tip. In addition, surface contamination can result from the synthesis, production, packaging, weighing, compounding of hazardous drugs, and the like. This is especially true for those working in healthcare situations or laboratories.
BRIEF SUMMARY OF THE INVENTION
BRIEF SUMMARY OF THE INVENTION
[005] The present invention relates to the discovery that a two part cleaning system cleans up hazardous drug surface contamination better than existing cleaning systems and methods. By cleaning first with a quaternary ammonium solution followed in successive order by a isopropyl alcohol and water solution hazardous drug products are cleaned up without leaving detectable residues form the surfaces.
[006] In one embodiment, the present invention relates to a method of cleaning a surface contaminated with a hazardous drug product comprising:
a) wiping the surface a first time with a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%; and b) wiping the surface a second time in succession with a second solution of water and isopropyl alcohol; the isopropyl alcohol comprising at least about 50% of the solution.
a) wiping the surface a first time with a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%; and b) wiping the surface a second time in succession with a second solution of water and isopropyl alcohol; the isopropyl alcohol comprising at least about 50% of the solution.
[007] In another embodiment, it relates to a system for cleaning a surface contaminated with a hazardous drug product comprising a first towelette impregnated with a solution of a quaternary ammonium solution having a concentration of from about 0.5% to about 5.0% and a second towelette impregnated with a water and isopropyl alcohol solution the isopropyl alcohol comprising at least about 50% of the solution.
[008] In yet another embodiment, it relates to a kit of parts for cleaning a surface contaminated with a hazardous drug product comprising:
a) a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%;
b) a second solution of water and isopropyl alcohol, the isopropyl alcohol comprising at least about 50% of the solution; and c) instructions for cleaning the contaminated surface with each of the solutions in succession.
DETAILED DESCRIPTION OF THE INVENTION
a) a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%;
b) a second solution of water and isopropyl alcohol, the isopropyl alcohol comprising at least about 50% of the solution; and c) instructions for cleaning the contaminated surface with each of the solutions in succession.
DETAILED DESCRIPTION OF THE INVENTION
[009] While this invention is susceptible to embodiment in many different forms, there is shown in the drawings and will herein be described in detail specific embodiments, with the understanding that the present disclosure of such embodiments is to be considered as an example of the principles and not intended to limit the invention to the specific embodiments shown and described. In the description below, like reference numerals are used to describe the same, similar or corresponding parts in the several views of the drawings. This detailed description defines the meaning of the terms used herein and specifically describes embodiments in order for those skilled in the art to practice the invention.
DEFINITIONS
DEFINITIONS
[010] The terms "about" and "essentially" mean 10 percent.
[011] The terms "a" or "an", as used herein, are defined as one or as more than one. The term "plurality", as used herein, is defined as two or as more than two. The term "another", as used herein, is defined as at least a second or more. The terms "including" and/or "having", as used herein, are defined as comprising (i.e., open language). The term "coupled", as used herein, is defined as connected, although not necessarily directly, and not necessarily mechanically.
[012] The term "comprising" is not intended to limit inventions to only claiming the present invention with such comprising language. Any invention using the term comprising could be separated into one or more claims using "consisting" or "consisting of' claim language and is so intended.
[013] Reference throughout this document to "one embodiment" "certain embodiments" and "an embodiment" or similar terms means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present invention. Thus, the appearances of such phrases or in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any suitable manner in one or more embodiments without limitation.
[014] The term "or" as used herein is to be interpreted as an inclusive or meaning any one or any combination. Therefore, "A, B or C" means any of the following:
"A;
B; C; A and B; A and C; B and C; A, B and C". An exception to this definition will occur only when a combination of elements, functions, steps or acts are in some way inherently mutually exclusive.
"A;
B; C; A and B; A and C; B and C; A, B and C". An exception to this definition will occur only when a combination of elements, functions, steps or acts are in some way inherently mutually exclusive.
[015] The drawings featured in the figures are for the purpose of illustrating certain convenient embodiments of the present invention, and are not to be considered as limitation thereto. Term "means" preceding a present participle of an operation indicates a desired function for which there is one or more embodiments, i.e., one or more methods, devices, or apparatuses for achieving the desired function and that one skilled in the art could select from these or their equivalent in view of the disclosure herein and use of the term "means" is not intended to be limiting.
[016] As used herein the term "cleaning" refers to the removal of contamination on a selected surface. In particular, it relates to removal of hazardous drugs, and hazardously related products (e.g. breakdown products and products used to make the hazardous decay) from the surface. In general, removal relates to removal of such contaminants to a degree that all detectable residues of a hazardous drug product are removed. Surfaces include but are not limited to countertops, equipment, walls, floors, and essentially any solid surface that is compatible with the ingredients being used to clean the surface.
[017] As used herein the term "surface" refers to any solid surface that one would encounter hazardous drug contamination. For example, in drug manufacture, drug discovery and drug dispensing, counters, walls, equipment, cabinets and the like in the environment may need to be cleaned of drug contamination. This is especially true where Federal regulation dictates certain levels of cleanliness to operate a business.
[018] The term "towelette" as used herein, generally includes any napkin, paper towel, tissue, fabric, cloth, or similar rnaterial, or any other object suitable for applying the solutions of the present invention to the surface to be cleaned.
The towelette can be reusable or disposable as desired. A disposable towelette usually refers to low cost materials designed for a single use, such as made with paper or very inexpensive cloth or other materials since all materials can be disposed of. The material must be absorbent enough to impregnate the towelette with each of the solutions. Therefore, the material for each solution can be the same or can be different depending on the characteristics desired. Since it is intended for dean-up of a hazardous drug product, it will need to be capable of having the product stuck or be absorbed in slurry or solution onto the surface of the towelette before disposal.
The size of the towelette is, by choice, the size of the area to be cleaned in, and therefore is within the skill in the art if the towelette is small or large in view of the disclosure herein.
The towelette can be reusable or disposable as desired. A disposable towelette usually refers to low cost materials designed for a single use, such as made with paper or very inexpensive cloth or other materials since all materials can be disposed of. The material must be absorbent enough to impregnate the towelette with each of the solutions. Therefore, the material for each solution can be the same or can be different depending on the characteristics desired. Since it is intended for dean-up of a hazardous drug product, it will need to be capable of having the product stuck or be absorbed in slurry or solution onto the surface of the towelette before disposal.
The size of the towelette is, by choice, the size of the area to be cleaned in, and therefore is within the skill in the art if the towelette is small or large in view of the disclosure herein.
[019] Medical, nursing, pharmacy and laboratory personnel that are involved in the preparation, use and administration of hazardous drugs suffer the risk of being exposed to the drugs or the compositions used in the manufacture and delivery of drugs, which may escape to the surrounding surfaces and thus come into contact with personnel utilizing the surfaces or coming in contact with them. As used herein, a "hazardous drug product" is any material the contact with which may constitute a health hazard. This includes the drugs themselves the precursors, side products, solvents utilized therewith and the like connected with the drugs themselves.
Illustrative and non-lirnitative examples of such drugs include, inter alia, cytotoxins, antiviral drugs, chemotherapy drugs, antibiotics, and radiopharmaceuticals, such as herceptin, cisplatinum, fluorouracil, leucovorin, taxol, metatroxat, gemzar, cyclophosphamide, Cytoxan, and neosar, or a combination thereof, in a liquid or solid state. Other examples of hazardous drug products include docetaxel, paclitaxel, 5-fluorouracil, cyclophosphamide, ifosfamide and cisplatin. Contaminated then refers to the hazardous drug product being on a surface where someone can come into contact with the drug product.
Illustrative and non-lirnitative examples of such drugs include, inter alia, cytotoxins, antiviral drugs, chemotherapy drugs, antibiotics, and radiopharmaceuticals, such as herceptin, cisplatinum, fluorouracil, leucovorin, taxol, metatroxat, gemzar, cyclophosphamide, Cytoxan, and neosar, or a combination thereof, in a liquid or solid state. Other examples of hazardous drug products include docetaxel, paclitaxel, 5-fluorouracil, cyclophosphamide, ifosfamide and cisplatin. Contaminated then refers to the hazardous drug product being on a surface where someone can come into contact with the drug product.
[020] The system comprises a first cleaning and a second cleaning. In this system, a process whereby the surface is first cleaned with a solution of a quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%. The solution, in other embodiments, can be 1 to 3% or the like. In other embodiments the solution can be impregnated on a reusable or disposable towelette. Next, after the first cleaning, a second cleaning in succession is performed. In succession refers to a time period right after the first cleaning such that there is little or no time for the surface to be recontaminated such as mere seconds but within a reasonable time period. The second cleaning is performed with a second solution of water and isopropyl alcohol, the isopropyl alcohol comprising at least about 50% of the solution.
The towelettes or whatever is utilized to apply the solutions can be disposed of in hazardous waste containers or the like or reutilized after appropriate cleaning. The solutions can be delivered for application by a user to a towelette or can be impregnated onto a towelette for use.
The towelettes or whatever is utilized to apply the solutions can be disposed of in hazardous waste containers or the like or reutilized after appropriate cleaning. The solutions can be delivered for application by a user to a towelette or can be impregnated onto a towelette for use.
[021] In one embodiment, there is a kit of parts wherein the first and second solution are packaged or otherwise delivered, along with instructions for use in cleaning a hazardous drug product from a surface by utzing a first wiping and a second wiping with each of the solutions in succession. In one embodiment the quaternary ammonium solution is utzed to wipe the surface first.
[022] Those skilled in the art to which the present invention pertains may make modifications resulting in other embodiments employing principles of the present invention without departing from its spirit or characteristics, particularly upon considering the foregoing teachings. Accordingly, the described embodiments are to be considered in all respects only as illustrative, and not restrictive, and the scope of the present invention is, therefore, indicated by the appended claims rather than by the foregoing description or drawings. Consequently, while the present invention has been described with reference to particular embodiments, modifications of structure, sequence, materials, and the like, apparent to those skilled in the art still fall within the scope of the invention as claimed by the applicant.
Claims (7)
1. A method of cleaning a surface contaminated with a hazardous drug or hazardous drug related products comprising:
a) wiping the surface a first time with a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%; and b) wiping the surface a second time in succession with a second solution of water and isopropyl alcohol the isopropyl alcohol comprising at least about 50% of the solution.
a) wiping the surface a first time with a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%; and b) wiping the surface a second time in succession with a second solution of water and isopropyl alcohol the isopropyl alcohol comprising at least about 50% of the solution.
2. The method according to claim 1 wherein each of the first solution and second solution are impregnated on to a towelette.
3. The method according to claim 2 wherein the towelette is disposable.
4. The method according to claim 1 wherein the hazardous drug product is at least one of docetaxel, paclitaxel, 5-fluorouracil, cyclophosphamide, ifosfamide and cisplatin.
5. A system for cleaning a surface contaminated with a hazardous drug product comprising a first towelette impregnated with a solution of a quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%
and a second towelette impregnated with a water and isopropyl alcohol solution the isopropyl alcohol comprising at least about 50% of the solution.
and a second towelette impregnated with a water and isopropyl alcohol solution the isopropyl alcohol comprising at least about 50% of the solution.
6. A kit of parts for cleaning a surface contaminated with a hazardous drug product comprising:
d) a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%;
e) a second solution of water and isopropyl alcohol the isopropyl alcohol comprising at least about 50% of the solution; and f) instructions for cleaning the contaminated surface with each of the solutions in succession.
d) a first solution of an quaternary ammonium solution having a concentration of from about 0.5% to about 5.0%;
e) a second solution of water and isopropyl alcohol the isopropyl alcohol comprising at least about 50% of the solution; and f) instructions for cleaning the contaminated surface with each of the solutions in succession.
7. The kit of parts according to claim 5 wherein each of the solutions is impregnated on a towelette.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361788426P | 2013-03-15 | 2013-03-15 | |
US61/788,426 | 2013-03-15 | ||
PCT/US2014/028008 WO2014143857A1 (en) | 2013-03-15 | 2014-03-14 | System and method for hazardous drug surface cleaning |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2902728A1 true CA2902728A1 (en) | 2014-09-18 |
Family
ID=51537545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2902728A Abandoned CA2902728A1 (en) | 2013-03-15 | 2014-03-14 | System and method for hazardous drug surface cleaning |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2970833A4 (en) |
CA (1) | CA2902728A1 (en) |
MX (1) | MX2015012659A (en) |
WO (1) | WO2014143857A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10138448B2 (en) * | 2016-04-11 | 2018-11-27 | Veltek Associates, Inc | Deactivation wipe kit |
USD958537S1 (en) | 2020-03-19 | 2022-07-26 | Veltek Associates, Inc. | Pouch with multiple compartments |
USD962786S1 (en) | 2020-09-11 | 2022-09-06 | Veltek Associates, Inc. | Pouch with multiple compartments |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070283514A1 (en) * | 2006-06-07 | 2007-12-13 | Burgwin Rebecca W | Sanitary seat wipes |
US20120034287A1 (en) * | 2010-08-03 | 2012-02-09 | Napolitano Lisa A | Quaternary Ammonium Glycol Ether Disinfectant Wipes |
-
2014
- 2014-03-14 EP EP14764055.1A patent/EP2970833A4/en not_active Withdrawn
- 2014-03-14 MX MX2015012659A patent/MX2015012659A/en unknown
- 2014-03-14 CA CA2902728A patent/CA2902728A1/en not_active Abandoned
- 2014-03-14 WO PCT/US2014/028008 patent/WO2014143857A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
MX2015012659A (en) | 2016-10-21 |
EP2970833A1 (en) | 2016-01-20 |
EP2970833A4 (en) | 2016-12-07 |
WO2014143857A1 (en) | 2014-09-18 |
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