CA2901923C - Device, system and methods for the oral delivery of therapeutic compounds - Google Patents
Device, system and methods for the oral delivery of therapeutic compounds Download PDFInfo
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- CA2901923C CA2901923C CA2901923A CA2901923A CA2901923C CA 2901923 C CA2901923 C CA 2901923C CA 2901923 A CA2901923 A CA 2901923A CA 2901923 A CA2901923 A CA 2901923A CA 2901923 C CA2901923 C CA 2901923C
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- OGBMKVWORPGQRR-UMXFMPSGSA-N teriparatide Chemical compound C([C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CNC=N1 OGBMKVWORPGQRR-UMXFMPSGSA-N 0.000 description 1
- 229960005460 teriparatide Drugs 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 229960003726 vasopressin Drugs 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Surgical Instruments (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3104670A CA3104670C (en) | 2013-03-15 | 2014-03-12 | DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/837,025 US8734429B2 (en) | 2010-12-23 | 2013-03-15 | Device, system and methods for the oral delivery of therapeutic compounds |
| US13/837,025 | 2013-03-15 | ||
| PCT/US2014/024385 WO2014159604A1 (en) | 2013-03-15 | 2014-03-12 | Device for oral delivery of therapeutic compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3104670A Division CA3104670C (en) | 2013-03-15 | 2014-03-12 | DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2901923A1 CA2901923A1 (en) | 2014-10-02 |
| CA2901923C true CA2901923C (en) | 2021-12-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA3240667A Pending CA3240667A1 (en) | 2013-03-15 | 2014-03-12 | Device for oral delivery of therapeutic compounds |
| CA3104670A Active CA3104670C (en) | 2013-03-15 | 2014-03-12 | DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS |
| CA2901923A Active CA2901923C (en) | 2013-03-15 | 2014-03-12 | Device, system and methods for the oral delivery of therapeutic compounds |
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| Application Number | Title | Priority Date | Filing Date |
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| CA3240667A Pending CA3240667A1 (en) | 2013-03-15 | 2014-03-12 | Device for oral delivery of therapeutic compounds |
| CA3104670A Active CA3104670C (en) | 2013-03-15 | 2014-03-12 | DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP2968071B1 (OSRAM) |
| JP (5) | JP6796484B2 (OSRAM) |
| CN (1) | CN105263461B (OSRAM) |
| AU (4) | AU2014240401B2 (OSRAM) |
| CA (3) | CA3240667A1 (OSRAM) |
| DK (1) | DK2968071T3 (OSRAM) |
| ES (1) | ES2897795T3 (OSRAM) |
| PL (1) | PL2968071T3 (OSRAM) |
| PT (1) | PT2968071T (OSRAM) |
| WO (1) | WO2014159604A1 (OSRAM) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102770151B (zh) | 2009-08-03 | 2018-07-31 | 因卡伯实验室有限责任公司 | 用于刺激肠道内肠促胰岛素产生的吞咽式囊和方法 |
| US8562589B2 (en) | 2009-12-24 | 2013-10-22 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| AU2014240401B2 (en) * | 2013-03-15 | 2018-11-15 | Rani Therapeutics, Llc | Device for oral delivery of therapeutic compounds |
| WO2017156347A1 (en) * | 2016-03-09 | 2017-09-14 | Incube Labs, Llc | Methods and articles for delivering viable cells into solid tissue |
| KR102737336B1 (ko) * | 2016-09-09 | 2024-12-05 | 비오라 쎄라퓨틱스, 인크. | 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스 |
| DK3624887T3 (da) * | 2017-05-17 | 2025-05-19 | Massachusetts Inst Technology | Vævforankringsartikler |
| US10675248B2 (en) * | 2018-08-14 | 2020-06-09 | Alma Therapeutics Ltd. | Expandable pill |
| US12128133B2 (en) * | 2018-09-25 | 2024-10-29 | Rani Therapeutics, Llc | Ingestible device with expandable enclosure |
| CN109621169B (zh) * | 2019-01-09 | 2021-06-08 | 李红岩 | 一种产科观察治疗仪 |
| CN113329777B (zh) | 2019-02-01 | 2024-01-09 | 诺和诺德股份有限公司 | 具有致动机构的医疗装置 |
| CN114650864B (zh) * | 2019-10-01 | 2024-12-03 | 拉尼医疗有限公司 | 用于将制剂递送到管腔壁的自定尺寸装置 |
| AU2021207614A1 (en) * | 2020-01-14 | 2022-09-08 | Rani Therapeutics, Llc | Swallowable devices for drug delivery in an intestinal tract |
| EP4125806B1 (en) * | 2020-03-31 | 2024-10-16 | Danmarks Tekniske Universitet | A flexible foil for the delivery of therapeutic cargos |
| WO2022055779A1 (en) * | 2020-09-09 | 2022-03-17 | Amgen Inc. | Swallowable drug delivery devices |
| WO2022090551A1 (en) * | 2020-11-02 | 2022-05-05 | Novo Nordisk A/S | Substance delivering capsule |
| US20240149031A1 (en) * | 2021-03-05 | 2024-05-09 | Bitherapeutics Inc. | Oral drug delivery device |
| JP2025505788A (ja) * | 2022-02-21 | 2025-02-28 | ラニ セラピューティクス， エルエルシー | 流体製剤を消化管内部に送達するためのデバイス、アセンブリ及び方法 |
| CN118900706A (zh) * | 2022-02-21 | 2024-11-05 | 拉尼医疗有限公司 | 用于将流体制剂递送到胃肠道的可摄入装置 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5125414A (en) * | 1990-01-16 | 1992-06-30 | Dysarz Edward D | Trap in barrel one handed retracted blood sampling device |
| US5217449A (en) * | 1990-12-11 | 1993-06-08 | Miyarisan Kabushiki Kaisha | Medical capsule and apparatus for activating the same |
| US5279607A (en) * | 1991-05-30 | 1994-01-18 | The State University Of New York | Telemetry capsule and process |
| CA2286002C (en) * | 1997-04-10 | 2008-01-29 | Andrew N. Lamborne | Gaz syringe and package therefor |
| GB9930000D0 (en) * | 1999-12-21 | 2000-02-09 | Phaeton Research Ltd | An ingestible device |
| BR0116973A (pt) * | 2001-04-13 | 2004-10-13 | Becton Dickinson Co | Método de injetar substâncias de forma intradérmica |
| US7160258B2 (en) * | 2001-06-26 | 2007-01-09 | Entrack, Inc. | Capsule and method for treating or diagnosing the intestinal tract |
| EP1594477A4 (en) * | 2003-01-29 | 2009-07-15 | Pill Pharma Ltd E | ACTIVE MEDICATION CONTRIBUTION IN THE DIGESTIVE TUBE |
| US20050058701A1 (en) * | 2003-01-29 | 2005-03-17 | Yossi Gross | Active drug delivery in the gastrointestinal tract |
| CN2860501Y (zh) * | 2005-03-10 | 2007-01-24 | 李华 | 一次性注射器 |
| US8021357B2 (en) * | 2005-05-27 | 2011-09-20 | Olympus Corporation | Body-insertable apparatus |
| JP4402648B2 (ja) * | 2005-12-16 | 2010-01-20 | オリンパス株式会社 | 被検体内導入装置 |
| WO2010045477A2 (en) * | 2008-10-16 | 2010-04-22 | Obalon Therapeutics, Inc. | Intragastric volume-occupying device and method for fabricating same |
| US8562589B2 (en) * | 2009-12-24 | 2013-10-22 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
| CN105999526B (zh) * | 2009-12-24 | 2019-07-05 | 拉尼医疗有限公司 | 可吞咽式药剂递送装置和药剂递送方法 |
| US8734429B2 (en) * | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| CA2840487C (en) * | 2011-06-29 | 2022-09-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
| EP3653224A1 (en) * | 2011-06-29 | 2020-05-20 | Rani Therapeutics, LLC | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| AU2014240401B2 (en) | 2013-03-15 | 2018-11-15 | Rani Therapeutics, Llc | Device for oral delivery of therapeutic compounds |
-
2014
- 2014-03-12 AU AU2014240401A patent/AU2014240401B2/en active Active
- 2014-03-12 EP EP14775797.5A patent/EP2968071B1/en active Active
- 2014-03-12 PT PT147757975T patent/PT2968071T/pt unknown
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- 2014-03-12 JP JP2016501518A patent/JP6796484B2/ja active Active
- 2014-03-12 CA CA3104670A patent/CA3104670C/en active Active
- 2014-03-12 PL PL14775797T patent/PL2968071T3/pl unknown
- 2014-03-12 DK DK14775797.5T patent/DK2968071T3/da active
- 2014-03-12 CN CN201480015725.6A patent/CN105263461B/zh active Active
- 2014-03-12 CA CA2901923A patent/CA2901923C/en active Active
- 2014-03-12 ES ES14775797T patent/ES2897795T3/es active Active
- 2014-03-12 WO PCT/US2014/024385 patent/WO2014159604A1/en not_active Ceased
- 2014-03-12 EP EP21189226.0A patent/EP3964190A1/en active Pending
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2018
- 2018-12-26 JP JP2018242716A patent/JP2019069206A/ja not_active Withdrawn
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2019
- 2019-02-13 AU AU2019201008A patent/AU2019201008B2/en active Active
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2020
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2021
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2022
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2024
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Also Published As
| Publication number | Publication date |
|---|---|
| CN105263461B (zh) | 2019-09-10 |
| DK2968071T3 (da) | 2021-11-08 |
| JP6796484B2 (ja) | 2020-12-09 |
| EP2968071A1 (en) | 2016-01-20 |
| CN105263461A (zh) | 2016-01-20 |
| AU2019201008B2 (en) | 2021-03-25 |
| JP2021020110A (ja) | 2021-02-18 |
| AU2023222952A1 (en) | 2023-09-21 |
| EP2968071A4 (en) | 2016-10-05 |
| AU2014240401B2 (en) | 2018-11-15 |
| JP2019069206A (ja) | 2019-05-09 |
| EP2968071B1 (en) | 2021-08-04 |
| JP2022162094A (ja) | 2022-10-21 |
| JP2016511124A (ja) | 2016-04-14 |
| PL2968071T3 (pl) | 2021-12-20 |
| AU2023222952B2 (en) | 2025-06-05 |
| EP3964190A1 (en) | 2022-03-09 |
| CA3104670C (en) | 2024-10-08 |
| AU2019201008A1 (en) | 2019-03-07 |
| CA3240667A1 (en) | 2014-10-02 |
| AU2021203778B2 (en) | 2023-06-01 |
| CA3104670A1 (en) | 2014-10-02 |
| AU2014240401A1 (en) | 2015-09-10 |
| JP7434462B2 (ja) | 2024-02-20 |
| JP2024036622A (ja) | 2024-03-15 |
| ES2897795T3 (es) | 2022-03-02 |
| AU2021203778A1 (en) | 2021-07-22 |
| CA2901923A1 (en) | 2014-10-02 |
| WO2014159604A1 (en) | 2014-10-02 |
| PT2968071T (pt) | 2021-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190306 |