CA2893883A1 - Delphinidin for combating melanoma cells - Google Patents
Delphinidin for combating melanoma cells Download PDFInfo
- Publication number
- CA2893883A1 CA2893883A1 CA2893883A CA2893883A CA2893883A1 CA 2893883 A1 CA2893883 A1 CA 2893883A1 CA 2893883 A CA2893883 A CA 2893883A CA 2893883 A CA2893883 A CA 2893883A CA 2893883 A1 CA2893883 A1 CA 2893883A1
- Authority
- CA
- Canada
- Prior art keywords
- delphinidin
- composition
- cells
- sbe
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nanotechnology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102012222777 | 2012-12-11 | ||
| DE102012222777.6 | 2012-12-11 | ||
| EP13150909 | 2013-01-11 | ||
| EP13150909.3 | 2013-01-11 | ||
| PCT/EP2013/074991 WO2014090586A1 (de) | 2012-12-11 | 2013-11-28 | Delphinidin zur bekämpfung von melanomzellen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2893883A1 true CA2893883A1 (en) | 2014-06-19 |
Family
ID=49679524
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2893883A Abandoned CA2893883A1 (en) | 2012-12-11 | 2013-11-28 | Delphinidin for combating melanoma cells |
| CA2893881A Expired - Fee Related CA2893881C (en) | 2012-12-11 | 2013-11-28 | Delphinidin for combating melanoma cells |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2893881A Expired - Fee Related CA2893881C (en) | 2012-12-11 | 2013-11-28 | Delphinidin for combating melanoma cells |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9511047B2 (enExample) |
| EP (2) | EP2931286B1 (enExample) |
| JP (2) | JP6234476B2 (enExample) |
| KR (2) | KR20150107742A (enExample) |
| CN (2) | CN104918622A (enExample) |
| CA (2) | CA2893883A1 (enExample) |
| HK (1) | HK1215392A1 (enExample) |
| WO (2) | WO2014090586A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2890022C (en) | 2012-11-15 | 2020-07-14 | Sapiotec Gmbh | Delphinidin complex as an antiphlogistic or immunosuppressive active ingredient |
| CA2893883A1 (en) | 2012-12-11 | 2014-06-19 | Sapiotec Gmbh | Delphinidin for combating melanoma cells |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5946228A (ja) | 1982-09-08 | 1984-03-15 | Zeria Shinyaku Kogyo Kk | 生物学的に活性な有機化合物の水溶性及びリンパ移行性薬剤の製造方法 |
| HU199444B (en) | 1985-09-10 | 1990-02-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom |
| GB8907008D0 (en) | 1989-03-28 | 1989-05-10 | Inverni Della Beffa Spa | Intermediates useful for the synthesis for delphinidin chloride |
| US5376645A (en) * | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| ZA962214B (en) | 1995-04-10 | 1996-10-07 | Farmarc Nederland Bv | Pharmaceutical composition |
| KR101004174B1 (ko) * | 1995-06-29 | 2010-12-24 | 임뮤넥스 코포레이션 | 세포소멸을 유도하는 시토킨 |
| GB2307176A (en) | 1995-11-15 | 1997-05-21 | Todd Selwyn Everest | Anti-inflammatory clathrating agents for topical use |
| HUP9701945A3 (en) | 1997-11-10 | 2000-04-28 | Hexal Ag | Pharmaceutical composition for injection containing cyclodextrin and taxoids |
| JP4101346B2 (ja) | 1998-02-18 | 2008-06-18 | ダイセル化学工業株式会社 | 酸化触媒系及びそれを用いた酸化方法 |
| AU759280C (en) | 1998-02-23 | 2004-01-22 | Cyclops, Ehf | High-energy cyclodextrin complexes |
| US6699849B1 (en) | 1998-02-23 | 2004-03-02 | Cyclops, Ehf. | Cyclodextrin complexes of benzodiazepines |
| GB2350297A (en) | 1999-05-27 | 2000-11-29 | Abbott Lab | Injectable halogenated anesthetic formulation in emulsion form |
| EP1232187A1 (en) | 1999-08-11 | 2002-08-21 | Josef Pitha | Potentiation of inclusion complex formation of cyclodextrin derivatives |
| AU7937500A (en) | 1999-10-27 | 2001-05-08 | Farmarc Nederland Bv | Pharmaceutical composition containing midazolam |
| ATE309262T1 (de) | 2000-09-12 | 2005-11-15 | Meiji Seika Kaisha | Verfahren zur herstellung von aufgereinigtem anthocyanin und kristallines anthocyanin |
| US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
| CA2441744C (en) | 2001-03-20 | 2011-07-12 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
| JP2003171274A (ja) | 2001-12-07 | 2003-06-17 | Tomihiko Higuchi | 薬剤耐性菌感染症治療のための医薬組成物および消毒剤 |
| JP2005522422A (ja) | 2002-02-01 | 2005-07-28 | シモダ、バイオテック(プロプライエタリー)リミテッド | 医薬組成物 |
| JP2004238336A (ja) * | 2003-02-07 | 2004-08-26 | Sanei Gen Ffi Inc | 水易溶性包接フラボノイド類の製造方法 |
| US20050013880A1 (en) * | 2003-03-06 | 2005-01-20 | Magnuson Bernadene Ann | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth |
| KR20060011943A (ko) | 2003-03-28 | 2006-02-06 | 아이박스 코포레이션 | 향상된 경구 및 경점막 수송용 클라드리빈 제형 |
| US20090192230A1 (en) | 2004-01-14 | 2009-07-30 | Koichi Takeda | Propofol-containing fat emulsion preparation |
| CN1317961C (zh) | 2004-03-25 | 2007-05-30 | 吴朝琴 | 冻干草莓加工工艺 |
| CN100342026C (zh) * | 2004-05-13 | 2007-10-10 | 深圳新鹏生物工程有限公司 | 重组人可溶性肿瘤坏死因子相关凋亡诱导配体制备方法 |
| WO2006076387A2 (en) * | 2005-01-11 | 2006-07-20 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Cyanidin-3-glucoside as an anti-neoplastic agent |
| DE102005017775A1 (de) | 2005-04-13 | 2006-10-19 | Schering Ag | Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins |
| KR100733913B1 (ko) * | 2005-08-30 | 2007-07-02 | 한국화학연구원 | 안토시아닌을 포함하는 뇌세포 보호제와 뇌경색 및 뇌졸중예방 또는 치료제 |
| US7645748B2 (en) | 2006-04-03 | 2010-01-12 | Forbes Medi-Tech Inc. | Sterol/stanol phosphorylnitroderivatives and use thereof |
| JP5569899B2 (ja) | 2006-11-28 | 2014-08-13 | ウィスコンシン・アラムナイ・リサーチ・ファウンデーション | 揮発性のフッ化麻酔薬を静脈内送達するためのフルオロポリマーベースのエマルション |
| KR100756656B1 (ko) | 2006-12-12 | 2007-09-10 | 한국화학연구원 | 안토시아닌을 포함하는 뇌경색 또는 뇌졸중 예방 및 개선용건강식품 |
| KR100880876B1 (ko) | 2007-04-11 | 2009-01-30 | 경상대학교산학협력단 | 검정콩 껍질로부터 추출한 안토시아닌을 함유하는 피판이나조직의 허혈-재관류 손상의 예방 또는 치료용 의약 조성물 |
| WO2009018326A2 (en) | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Soluble pyrone analogs methods and compositions |
| JP5574600B2 (ja) | 2007-12-17 | 2014-08-20 | 日本製薬工業株式会社 | 吸収性骨疾患の予防・治療剤 |
| EP2106786A1 (de) | 2008-04-04 | 2009-10-07 | Roewer, Norbert, Univ.-Prof. Dr. med. | Pharmazeutische Zubereitung mit permethyliertem Cyclodextrin |
| US7635773B2 (en) * | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| WO2010110328A1 (ja) | 2009-03-25 | 2010-09-30 | 三栄源エフ・エフ・アイ株式会社 | 水易溶性イソクエルシトリン組成物 |
| EP2437770A4 (en) | 2009-06-05 | 2013-11-06 | Univ Colorado Regents | ANTIMICROBIAL PEPTIDES |
| ES2618952T3 (es) | 2009-10-21 | 2017-06-22 | Maqui New Life S.A. | Composiciones que incluyen antocianidinas y métodos de uso |
| EP2345427A1 (de) | 2010-01-14 | 2011-07-20 | SapioTec GmbH | Flurankomplex |
| CA2792733C (en) | 2010-03-13 | 2015-06-02 | Eastpond Laboratories Limited | Fat-binding compositions comprising .alpha.- or .beta.-cyclodextrin |
| DE102010042615A1 (de) | 2010-10-19 | 2012-04-19 | Wacker Chemie Ag | 1:1, 2:1- oder 3:1-Komplex bestehend aus einem Cyclodextrin oder Cyclodextrinderivat und einem halogeniertem Ether, seine Herstellung und seine Verwendung als Schlafmittel |
| RU2013133723A (ru) | 2010-12-31 | 2015-02-10 | Истпонд Лабораториз Лимитед | Композиции для клеточной гидратации, содержащие циклодекстрины |
| DK2484350T3 (en) | 2011-02-04 | 2016-08-01 | Norbert Univ -Prof Dr Med Roewer | A pharmaceutical composition containing a complex of a cyclodextrin with a propofolsalt |
| KR101905937B1 (ko) | 2012-03-30 | 2018-10-08 | 자피오텍 게엠베하 | 안토시아니딘 복합체 |
| US20150051273A1 (en) | 2012-03-30 | 2015-02-19 | Sapiotec Gmbh | Use of delphinidin against staphylococcus aureus |
| CN104780925A (zh) | 2012-10-17 | 2015-07-15 | 赛博尔泰克股份公司 | 用于治疗多发性骨髓瘤的花青素络合物 |
| CA2890022C (en) | 2012-11-15 | 2020-07-14 | Sapiotec Gmbh | Delphinidin complex as an antiphlogistic or immunosuppressive active ingredient |
| CA2893883A1 (en) | 2012-12-11 | 2014-06-19 | Sapiotec Gmbh | Delphinidin for combating melanoma cells |
| EP2913366A1 (de) | 2014-02-28 | 2015-09-02 | SapioTec GmbH | Anthocyanidin-Komplex |
| EP2913050A1 (de) | 2014-02-28 | 2015-09-02 | SapioTec GmbH | Verfahren zur Herstellung eines Flurankomplexes |
-
2013
- 2013-11-28 CA CA2893883A patent/CA2893883A1/en not_active Abandoned
- 2013-11-28 EP EP13798323.5A patent/EP2931286B1/de not_active Not-in-force
- 2013-11-28 KR KR1020157018732A patent/KR20150107742A/ko not_active Withdrawn
- 2013-11-28 US US14/651,264 patent/US9511047B2/en not_active Expired - Fee Related
- 2013-11-28 HK HK16103394.8A patent/HK1215392A1/zh unknown
- 2013-11-28 WO PCT/EP2013/074991 patent/WO2014090586A1/de not_active Ceased
- 2013-11-28 EP EP13815384.6A patent/EP2931287B1/de not_active Not-in-force
- 2013-11-28 KR KR1020157018731A patent/KR102164174B1/ko not_active Expired - Fee Related
- 2013-11-28 US US14/651,262 patent/US9949947B2/en not_active Expired - Fee Related
- 2013-11-28 JP JP2015546930A patent/JP6234476B2/ja not_active Expired - Fee Related
- 2013-11-28 CN CN201380064588.0A patent/CN104918622A/zh active Pending
- 2013-11-28 CN CN201380064614.XA patent/CN104936601A/zh active Pending
- 2013-11-28 CA CA2893881A patent/CA2893881C/en not_active Expired - Fee Related
- 2013-11-28 WO PCT/EP2013/074957 patent/WO2014090583A1/de not_active Ceased
- 2013-11-28 JP JP2015546927A patent/JP6234475B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2931287A1 (de) | 2015-10-21 |
| JP2016502984A (ja) | 2016-02-01 |
| EP2931286B1 (de) | 2017-10-04 |
| WO2014090586A1 (de) | 2014-06-19 |
| KR20150107742A (ko) | 2015-09-23 |
| KR20150107741A (ko) | 2015-09-23 |
| US9949947B2 (en) | 2018-04-24 |
| WO2014090583A1 (de) | 2014-06-19 |
| JP6234475B2 (ja) | 2017-11-22 |
| JP6234476B2 (ja) | 2017-11-22 |
| HK1216229A1 (zh) | 2016-10-28 |
| CA2893881C (en) | 2020-09-22 |
| CA2893881A1 (en) | 2014-06-19 |
| US20150320719A1 (en) | 2015-11-12 |
| JP2016502985A (ja) | 2016-02-01 |
| CN104918622A (zh) | 2015-09-16 |
| HK1215392A1 (zh) | 2016-08-26 |
| US20150328336A1 (en) | 2015-11-19 |
| US9511047B2 (en) | 2016-12-06 |
| EP2931287B1 (de) | 2017-10-04 |
| KR102164174B1 (ko) | 2020-10-12 |
| CN104936601A (zh) | 2015-09-23 |
| EP2931286A1 (de) | 2015-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20181105 |
|
| FZDE | Discontinued |
Effective date: 20210305 |