CA2892780A1 - Use of eribulin in the treatment of breast cancer - Google Patents
Use of eribulin in the treatment of breast cancer Download PDFInfo
- Publication number
- CA2892780A1 CA2892780A1 CA2892780A CA2892780A CA2892780A1 CA 2892780 A1 CA2892780 A1 CA 2892780A1 CA 2892780 A CA2892780 A CA 2892780A CA 2892780 A CA2892780 A CA 2892780A CA 2892780 A1 CA2892780 A1 CA 2892780A1
- Authority
- CA
- Canada
- Prior art keywords
- negative
- breast cancer
- her2
- subject
- eribulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
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Landscapes
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- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
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| US201261733238P | 2012-12-04 | 2012-12-04 | |
| US61/733,238 | 2012-12-04 | ||
| US201361878204P | 2013-09-16 | 2013-09-16 | |
| US61/878,204 | 2013-09-16 | ||
| PCT/IB2013/002911 WO2014087230A1 (en) | 2012-12-04 | 2013-12-04 | Use of eribulin in the treatment of breast cancer |
Publications (1)
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| CA2892780A1 true CA2892780A1 (en) | 2014-06-12 |
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| US (1) | US20140163095A1 (enExample) |
| EP (1) | EP2928464A1 (enExample) |
| JP (2) | JP6466339B2 (enExample) |
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| AU (2) | AU2013353745A1 (enExample) |
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| CA (1) | CA2892780A1 (enExample) |
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| MX (1) | MX2015007185A (enExample) |
| RU (1) | RU2689977C2 (enExample) |
| WO (1) | WO2014087230A1 (enExample) |
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| NZ595212A (en) | 2009-03-30 | 2014-02-28 | Eisai R&D Man Co Ltd | Liposome composition |
| EP3444363B1 (en) | 2011-06-03 | 2020-11-25 | Eisai R&D Management Co., Ltd. | Biomarkers for prediciting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
| WO2014087230A1 (en) * | 2012-12-04 | 2014-06-12 | Eisai R&D Management Co., Ltd. | Use of eribulin in the treatment of breast cancer |
| JP6644479B2 (ja) * | 2014-06-24 | 2020-02-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | がん治療のための併用療法としてのエリブリンとｓ−１（もしくは５−ｆｕ）の使用 |
| KR102329681B1 (ko) | 2014-08-28 | 2021-11-23 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 고순도의 퀴놀린 유도체 및 이를 제조하는 방법 |
| DK3263106T3 (da) | 2015-02-25 | 2024-01-08 | Eisai R&D Man Co Ltd | Fremgangsmåde til undertrykkelse af bitterhed af quinolinderivat |
| WO2016141209A1 (en) | 2015-03-04 | 2016-09-09 | Merck Sharp & Dohme Corp. | Combination of a pd-1 antagonist and eribulin for treating cancer |
| WO2016204193A1 (ja) | 2015-06-16 | 2016-12-22 | 株式会社ＰＲＩＳＭ Ｐｈａｒｍａ | 抗がん剤 |
| EP3338779B1 (en) | 2015-08-20 | 2021-06-30 | Eisai R&D Management Co., Ltd. | Lenvatinib in combination with etoposide and ifosfamide for use in treating a tumor |
| JP7015237B2 (ja) | 2016-04-28 | 2022-02-02 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍の成長を抑制する方法 |
| US12303505B2 (en) | 2017-02-08 | 2025-05-20 | Eisai R&D Management Co., Ltd. | Tumor-treating pharmaceutical composition |
| AU2018221371A1 (en) * | 2017-02-20 | 2019-08-22 | Polyphor Ag | Pharmaceutical combinations for treating cancer |
| CA3061888A1 (en) | 2017-05-16 | 2018-11-22 | Eisai R&D Management Co., Ltd. | Treatment of hepatocellular carcinoma |
| EP3654967A4 (en) * | 2017-07-21 | 2021-04-21 | Eisai R&D Management Co., Ltd. | USE OF EIBULIN AND CYCLINE-DEPENDENT KINASE INHIBITORS IN THE TREATMENT OF CANCER |
| WO2019097073A1 (en) | 2017-11-20 | 2019-05-23 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| AU2019215450A1 (en) * | 2018-02-05 | 2020-08-27 | Tesaro, Inc | Pediatric niraparib formulations and pediatric treatment methods |
| AU2019231321A1 (en) * | 2018-03-09 | 2020-10-15 | The Regents Of The University Of California | Combination treatment of chemoresistant cancers |
| CN113271977A (zh) * | 2018-11-09 | 2021-08-17 | G1治疗公司 | 使用艾日布林和选择性cdk4/6抑制剂组合治疗癌症的治疗方案 |
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| US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
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| EP2272839B1 (en) | 1998-06-17 | 2012-08-22 | Eisai R&D Management Co., Ltd. | Intermediate compounds for the preparation of halichondrin analogs |
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| KR20070114753A (ko) * | 2005-02-18 | 2007-12-04 | 아브락시스 바이오사이언스 인크. | 치료제의 조합 및 투여 방식, 및 조합 요법 |
| CA2922029C (en) * | 2006-03-22 | 2017-11-28 | Medigene Ag | A combination of a cationic liposomal preparation comprising an antimitotic agent and a non-liposomal preparation comprising an antimitotic agent |
| JP5735277B2 (ja) | 2007-10-03 | 2015-06-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ハリコンドリンｂ類似体の合成のための中間体および方法 |
| US8598373B2 (en) | 2008-04-04 | 2013-12-03 | Eisai R&D Management Co., Ltd. | Halichondrin B analogs |
| SG182612A1 (en) | 2010-01-26 | 2012-08-30 | Eisai R&D Man Co Ltd | Furo [3, 2 -b] pyrane derivatives useful in the synthesis of halichondrin b analogs |
| EP2686441B1 (en) * | 2011-03-18 | 2019-05-08 | Eisai R&D Management Co., Ltd. | Methods and uses for predicting response to eribulin |
| WO2014087230A1 (en) * | 2012-12-04 | 2014-06-12 | Eisai R&D Management Co., Ltd. | Use of eribulin in the treatment of breast cancer |
-
2013
- 2013-12-04 WO PCT/IB2013/002911 patent/WO2014087230A1/en not_active Ceased
- 2013-12-04 US US14/096,827 patent/US20140163095A1/en not_active Abandoned
- 2013-12-04 CA CA2892780A patent/CA2892780A1/en not_active Abandoned
- 2013-12-04 KR KR1020157017971A patent/KR20150090921A/ko not_active Ceased
- 2013-12-04 AU AU2013353745A patent/AU2013353745A1/en not_active Abandoned
- 2013-12-04 MX MX2015007185A patent/MX2015007185A/es unknown
- 2013-12-04 JP JP2015544557A patent/JP6466339B2/ja active Active
- 2013-12-04 RU RU2015126539A patent/RU2689977C2/ru active
- 2013-12-04 EP EP13826752.1A patent/EP2928464A1/en not_active Withdrawn
- 2013-12-04 BR BR112015012731A patent/BR112015012731A2/pt not_active Application Discontinuation
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2015
- 2015-05-25 IL IL239007A patent/IL239007B/en active IP Right Grant
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2018
- 2018-08-09 AU AU2018214086A patent/AU2018214086B2/en not_active Withdrawn - After Issue
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2019
- 2019-01-09 JP JP2019002177A patent/JP6678783B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014087230A1 (en) | 2014-06-12 |
| KR20150090921A (ko) | 2015-08-06 |
| AU2013353745A1 (en) | 2015-06-11 |
| JP2019089776A (ja) | 2019-06-13 |
| JP2016501213A (ja) | 2016-01-18 |
| RU2689977C2 (ru) | 2019-05-30 |
| BR112015012731A2 (pt) | 2017-07-11 |
| JP6678783B2 (ja) | 2020-04-08 |
| MX2015007185A (es) | 2017-09-05 |
| RU2015126539A (ru) | 2017-01-13 |
| AU2018214086B2 (en) | 2020-07-09 |
| JP6466339B2 (ja) | 2019-02-06 |
| EP2928464A1 (en) | 2015-10-14 |
| IL239007A0 (en) | 2015-07-30 |
| US20140163095A1 (en) | 2014-06-12 |
| IL239007B (en) | 2018-04-30 |
| AU2018214086A1 (en) | 2018-08-23 |
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