CA2889372C - Direct sample analysis device adapters and methods of using them - Google Patents
Direct sample analysis device adapters and methods of using them Download PDFInfo
- Publication number
- CA2889372C CA2889372C CA2889372A CA2889372A CA2889372C CA 2889372 C CA2889372 C CA 2889372C CA 2889372 A CA2889372 A CA 2889372A CA 2889372 A CA2889372 A CA 2889372A CA 2889372 C CA2889372 C CA 2889372C
- Authority
- CA
- Canada
- Prior art keywords
- sleeve
- capillary
- adapter
- mass spectrometer
- internal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000004458 analytical method Methods 0.000 title claims abstract description 117
- 238000000034 method Methods 0.000 title claims description 43
- 230000008878 coupling Effects 0.000 claims abstract description 110
- 238000010168 coupling process Methods 0.000 claims abstract description 110
- 238000005859 coupling reaction Methods 0.000 claims abstract description 110
- 239000012212 insulator Substances 0.000 claims abstract description 65
- 239000000463 material Substances 0.000 description 27
- 150000002500 ions Chemical class 0.000 description 26
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 12
- 229910010293 ceramic material Inorganic materials 0.000 description 11
- 229920000642 polymer Polymers 0.000 description 10
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 7
- 239000000919 ceramic Substances 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 239000012811 non-conductive material Substances 0.000 description 6
- 125000006850 spacer group Chemical group 0.000 description 6
- 229910001220 stainless steel Inorganic materials 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 239000010935 stainless steel Substances 0.000 description 5
- RUDFQVOCFDJEEF-UHFFFAOYSA-N yttrium(III) oxide Inorganic materials [O-2].[O-2].[O-2].[Y+3].[Y+3] RUDFQVOCFDJEEF-UHFFFAOYSA-N 0.000 description 5
- 238000003795 desorption Methods 0.000 description 4
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- -1 but not limited to Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
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- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 238000000065 atmospheric pressure chemical ionisation Methods 0.000 description 2
- 238000000451 chemical ionisation Methods 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 238000000132 electrospray ionisation Methods 0.000 description 2
- 238000010265 fast atom bombardment Methods 0.000 description 2
- 238000009616 inductively coupled plasma Methods 0.000 description 2
- 239000011810 insulating material Substances 0.000 description 2
- 238000005040 ion trap Methods 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 238000001004 secondary ion mass spectrometry Methods 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 238000004252 FT/ICR mass spectrometry Methods 0.000 description 1
- 239000004696 Poly ether ether ketone Substances 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013375 chromatographic separation Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
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- 238000009434 installation Methods 0.000 description 1
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- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920006260 polyaryletherketone Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920002530 polyetherether ketone Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000011819 refractory material Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
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- 238000006467 substitution reaction Methods 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0404—Capillaries used for transferring samples or ions
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/041—Controlled or regulated
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/662,500 US9412572B2 (en) | 2012-10-28 | 2012-10-28 | Sample holders and methods of using them |
US13/662,500 | 2012-10-28 | ||
US13/662,801 | 2012-10-29 | ||
US13/662,745 US9117641B2 (en) | 2012-10-29 | 2012-10-29 | Direct sample analysis device adapters and methods of using them |
US13/662,801 US9733156B2 (en) | 2012-10-29 | 2012-10-29 | Sample platforms and methods of using them |
US13/662,745 | 2012-10-29 | ||
PCT/US2013/066993 WO2014066872A2 (en) | 2012-10-28 | 2013-10-27 | Direct sample analysis device adapters and methods of using them |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2889372A1 CA2889372A1 (en) | 2014-05-01 |
CA2889372C true CA2889372C (en) | 2022-12-06 |
Family
ID=50545376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2889372A Active CA2889372C (en) | 2012-10-28 | 2013-10-27 | Direct sample analysis device adapters and methods of using them |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2912677B1 (zh) |
CN (1) | CN205582883U (zh) |
CA (1) | CA2889372C (zh) |
WO (1) | WO2014066872A2 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9590583B2 (en) | 2015-06-29 | 2017-03-07 | Agilent Technologies, Inc. | Alternating current (AC) coupler for wideband AC signals and related methods |
CN106769280B (zh) * | 2016-11-24 | 2019-10-29 | 中国石油大学(华东) | 一种简易海洋沉积物古地磁研究分样装置 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5157260A (en) * | 1991-05-17 | 1992-10-20 | Finnian Corporation | Method and apparatus for focusing ions in viscous flow jet expansion region of an electrospray apparatus |
US5965883A (en) * | 1997-08-25 | 1999-10-12 | California Institute Of Technology | Capillary for electrospray ion source |
US6248999B1 (en) * | 1998-09-24 | 2001-06-19 | Finnigan Corporation | Assembly for coupling an ion source to a mass analyzer |
US6794644B2 (en) * | 2000-02-18 | 2004-09-21 | Melvin A. Park | Method and apparatus for automating an atmospheric pressure ionization (API) source for mass spectrometry |
US6657191B2 (en) | 2001-03-02 | 2003-12-02 | Bruker Daltonics Inc. | Means and method for multiplexing sprays in an electrospray ionization source |
US7274015B2 (en) * | 2001-08-08 | 2007-09-25 | Sionex Corporation | Capacitive discharge plasma ion source |
US6707039B1 (en) * | 2002-09-19 | 2004-03-16 | Agilent Technologies, Inc. | AP-MALDI target illumination device and method for using an AP-MALDI target illumination device |
US7030373B2 (en) * | 2003-12-19 | 2006-04-18 | Applera Corporation | MALDI plate construction with grid |
JP4356491B2 (ja) * | 2004-03-26 | 2009-11-04 | 株式会社島津製作所 | ガスクロマトグラフ質量分析装置 |
US20060054805A1 (en) * | 2004-09-13 | 2006-03-16 | Flanagan Michael J | Multi-inlet sampling device for mass spectrometer ion source |
US7262841B2 (en) * | 2005-03-17 | 2007-08-28 | Agilent Technologies, Inc. | Laser alignment for ion source |
FR2886871B1 (fr) * | 2005-06-09 | 2008-10-17 | Centre Nat Rech Scient | Nebuliseur a debit nanometrique d'un effluent liquide et installation de nebulisation comportant un tel nebuliseur |
US7598488B2 (en) * | 2006-09-20 | 2009-10-06 | Park Melvin A | Apparatus and method for field asymmetric ion mobility spectrometry combined with mass spectrometry |
EP2160235B1 (en) * | 2007-06-01 | 2016-11-30 | Purdue Research Foundation | Discontinuous atmospheric pressure interface |
US8415619B2 (en) * | 2009-11-13 | 2013-04-09 | University of Glascgow | Methods and systems for mass spectrometry |
KR20110071320A (ko) * | 2009-12-21 | 2011-06-29 | 한국기초과학지원연구원 | 이온 주입기, 이를 포함하는 질량 분석기 및 이를 이용한 이온 집속 방법 |
-
2013
- 2013-10-27 CA CA2889372A patent/CA2889372C/en active Active
- 2013-10-27 CN CN201390001015.9U patent/CN205582883U/zh not_active Expired - Lifetime
- 2013-10-27 EP EP13849385.3A patent/EP2912677B1/en active Active
- 2013-10-27 WO PCT/US2013/066993 patent/WO2014066872A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2014066872A2 (en) | 2014-05-01 |
EP2912677B1 (en) | 2021-04-07 |
CN205582883U (zh) | 2016-09-14 |
WO2014066872A3 (en) | 2014-06-19 |
EP2912677A2 (en) | 2015-09-02 |
EP2912677A4 (en) | 2016-08-10 |
CA2889372A1 (en) | 2014-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20181022 |
|
EEER | Examination request |
Effective date: 20181022 |
|
EEER | Examination request |
Effective date: 20181022 |
|
EEER | Examination request |
Effective date: 20181022 |