CA2887326C - Reactifs de couplage multifonctionnels a fonction azlactone - Google Patents
Reactifs de couplage multifonctionnels a fonction azlactone Download PDFInfo
- Publication number
- CA2887326C CA2887326C CA2887326A CA2887326A CA2887326C CA 2887326 C CA2887326 C CA 2887326C CA 2887326 A CA2887326 A CA 2887326A CA 2887326 A CA2887326 A CA 2887326A CA 2887326 C CA2887326 C CA 2887326C
- Authority
- CA
- Canada
- Prior art keywords
- group
- aryl
- alkyl
- cio
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/36—One oxygen atom
- C07D263/42—One oxygen atom attached in position 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1259941 | 2012-10-18 | ||
| FR1259941A FR2997082B1 (fr) | 2012-10-18 | 2012-10-18 | Reactifs de couplage multifonctionnels a fonction azlactone. |
| PCT/EP2013/071430 WO2014060357A1 (fr) | 2012-10-18 | 2013-10-14 | Reactifs de couplage multifonctionnels a fonction azlactone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2887326A1 CA2887326A1 (fr) | 2014-04-24 |
| CA2887326C true CA2887326C (fr) | 2021-08-24 |
Family
ID=47428720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2887326A Active CA2887326C (fr) | 2012-10-18 | 2013-10-14 | Reactifs de couplage multifonctionnels a fonction azlactone |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9453843B2 (enExample) |
| EP (1) | EP2909185B1 (enExample) |
| JP (1) | JP6262746B2 (enExample) |
| CA (1) | CA2887326C (enExample) |
| ES (1) | ES2617967T3 (enExample) |
| FR (1) | FR2997082B1 (enExample) |
| WO (1) | WO2014060357A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170342211A1 (en) * | 2016-05-31 | 2017-11-30 | Robert Bosch Gmbh | Azlactone functionalized substrates for conjugation of biomolecules |
| FR3054546B1 (fr) | 2016-07-27 | 2019-06-28 | Universite Du Mans | Composes multifonctionnels, leurs procedes de preparation et leurs utilisations |
| CN110520522A (zh) | 2017-02-17 | 2019-11-29 | 鲁比厄斯治疗法股份有限公司 | 功能化红系细胞 |
| WO2019235019A1 (ja) * | 2018-06-05 | 2019-12-12 | ソニー株式会社 | 情報生成装置と情報生成方法およびプログラム |
| FR3126888A1 (fr) | 2021-09-15 | 2023-03-17 | Capsulae | Procédé pour la fabrication de capsules cœur – membrane, par polymérisation interfaciale |
| WO2026008825A1 (en) | 2024-07-05 | 2026-01-08 | Universite Du Mans | Cip3m, a sn38/gemcitabine conjugate and uses thereof in the treatment of cancers |
| WO2026055547A1 (en) | 2024-09-06 | 2026-03-12 | Flagship Pioneering Innovations Vii, Llc | Dna compositions and related methods |
| WO2026055543A1 (en) | 2024-09-06 | 2026-03-12 | Flagship Pioneering Innovations Vii, Llc | Modified dna compositions and related methods |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5344701A (en) * | 1992-06-09 | 1994-09-06 | Minnesota Mining And Manufacturing Company | Porous supports having azlactone-functional surfaces |
| US6894133B2 (en) | 2002-12-11 | 2005-05-17 | 3M Innovative Properties Company | Azlactone initiators for atom transfer radical polymerization |
| WO2004081538A2 (en) * | 2003-03-13 | 2004-09-23 | Irm, Llc | Compositions and methods of vinyl oxazolone polymerization |
| US6762257B1 (en) | 2003-05-05 | 2004-07-13 | 3M Innovative Properties Company | Azlactone chain transfer agents for radical polymerization |
-
2012
- 2012-10-18 FR FR1259941A patent/FR2997082B1/fr active Active
-
2013
- 2013-10-14 JP JP2015537211A patent/JP6262746B2/ja active Active
- 2013-10-14 ES ES13789199.0T patent/ES2617967T3/es active Active
- 2013-10-14 EP EP13789199.0A patent/EP2909185B1/fr active Active
- 2013-10-14 CA CA2887326A patent/CA2887326C/fr active Active
- 2013-10-14 WO PCT/EP2013/071430 patent/WO2014060357A1/fr not_active Ceased
- 2013-10-14 US US14/436,942 patent/US9453843B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150285811A1 (en) | 2015-10-08 |
| EP2909185A1 (fr) | 2015-08-26 |
| FR2997082B1 (fr) | 2015-02-13 |
| FR2997082A1 (fr) | 2014-04-25 |
| EP2909185B1 (fr) | 2016-12-07 |
| CA2887326A1 (fr) | 2014-04-24 |
| JP2016505506A (ja) | 2016-02-25 |
| WO2014060357A1 (fr) | 2014-04-24 |
| US9453843B2 (en) | 2016-09-27 |
| JP6262746B2 (ja) | 2018-01-17 |
| ES2617967T3 (es) | 2017-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180703 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - STANDARD Year of fee payment: 11 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20240924 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20240924 |