CA2884003A1 - Hyaluronic acid/collagen- based dermal filler compositions and methods for making same - Google Patents

Hyaluronic acid/collagen- based dermal filler compositions and methods for making same Download PDF

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Publication number
CA2884003A1
CA2884003A1 CA2884003A CA2884003A CA2884003A1 CA 2884003 A1 CA2884003 A1 CA 2884003A1 CA 2884003 A CA2884003 A CA 2884003A CA 2884003 A CA2884003 A CA 2884003A CA 2884003 A1 CA2884003 A1 CA 2884003A1
Authority
CA
Canada
Prior art keywords
collagen
hyaluronic acid
component
concentration
crosslinked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2884003A
Other languages
English (en)
French (fr)
Inventor
Jacob F. Pollock
Xiaojie Yu
Nicholas J. Manesis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/605,565 external-priority patent/US20130116188A1/en
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CA2884003A1 publication Critical patent/CA2884003A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04R—LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; ELECTRIC HEARING AIDS; PUBLIC ADDRESS SYSTEMS
    • H04R1/00—Details of transducers, loudspeakers or microphones
    • H04R1/10—Earpieces; Attachments therefor ; Earphones; Monophonic headphones
    • H04R1/1058—Manufacture or assembly
    • H04R1/1066—Constructional aspects of the interconnection between earpiece and earpiece support
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04R—LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; ELECTRIC HEARING AIDS; PUBLIC ADDRESS SYSTEMS
    • H04R1/00—Details of transducers, loudspeakers or microphones
    • H04R1/10—Earpieces; Attachments therefor ; Earphones; Monophonic headphones
    • H04R1/1058—Manufacture or assembly
    • H04R1/1075—Mountings of transducers in earphones or headphones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Signal Processing (AREA)
  • Molecular Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2884003A 2012-09-06 2013-09-05 Hyaluronic acid/collagen- based dermal filler compositions and methods for making same Abandoned CA2884003A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/605,565 2012-09-06
US13/605,565 US20130116188A1 (en) 2011-09-06 2012-09-06 Implantable hyaluronic acid/collagen compositions
PCT/US2013/058140 WO2014039607A1 (en) 2012-09-06 2013-09-05 Hyaluronic acid/collagen- based dermal filler compositions and methods for making same

Publications (1)

Publication Number Publication Date
CA2884003A1 true CA2884003A1 (en) 2014-03-13

Family

ID=52673764

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2884003A Abandoned CA2884003A1 (en) 2012-09-06 2013-09-05 Hyaluronic acid/collagen- based dermal filler compositions and methods for making same

Country Status (4)

Country Link
EP (2) EP3750568A1 (enExample)
JP (2) JP6389820B2 (enExample)
CA (1) CA2884003A1 (enExample)
WO (1) WO2014039607A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107189119A (zh) * 2017-07-24 2017-09-22 苏州景卓生物技术有限公司 一种复合玻尿酸胶原蛋白水凝胶的制备方法及其应用

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130116411A1 (en) * 2011-09-06 2013-05-09 Allergan, Inc. Methods of making hyaluronic acid/collagen compositions
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
JP6389820B2 (ja) * 2012-09-06 2018-09-12 アラーガン、インコーポレイテッドAllergan,Incorporated ヒアルロン酸/コラーゲン系真皮充填剤組成物およびそれを作製するための方法
WO2018159982A1 (ko) * 2017-02-28 2018-09-07 (주)시지바이오 피부 주입용 조성물
EP3590546B1 (en) * 2017-02-28 2024-08-21 CG Bio Co., Ltd. Composition for skin injection
BR112019017795B1 (pt) * 2017-02-28 2022-12-06 Cg Bio Co., Ltd. Composição para injeção dérmica
US11389563B2 (en) * 2017-06-12 2022-07-19 Advanced Aesthetic Technologies, Inc. Dermal filler
JP7184874B2 (ja) * 2018-03-28 2022-12-06 株式会社カネカ 接着剤組成物
KR102955766B1 (ko) 2018-05-03 2026-04-22 콜플랜트 리미티드 진피 충전제 및 이의 적용
KR102350526B1 (ko) * 2018-08-16 2022-01-17 (주)메디제이 응집성이 개선된 창상피복재 조성물의 제조 방법
CN119112703A (zh) * 2019-12-26 2024-12-13 阿勒根公司 物理混合ha-胶原蛋白皮肤填充物
US20230040919A1 (en) * 2019-12-26 2023-02-09 Allergan, Inc. Crosslinked ha-collagen hydrogels as dermal fillers
CN112535766B (zh) * 2020-12-11 2023-02-24 湖南美柏生物医药有限公司 基于人间充质干细胞细胞外基质来源复合胶原蛋白提取液水凝胶及其制备方法
CN113278170B (zh) * 2021-06-15 2021-11-16 苏州大学 一种化学交联透明质酸水凝胶及其制备方法与应用
CN114146223A (zh) * 2021-12-10 2022-03-08 三亚悦美科技有限公司 一种重组胶原蛋白复合注射剂及其制备方法
CN115154665B (zh) * 2022-06-08 2024-01-19 浙江驭远生物科技有限公司 含重组iii型人源胶原蛋白的润滑液、填充剂及其应用
CN117244112B (zh) * 2023-09-26 2026-01-27 瑞玞生物医学(深圳)有限公司 一种含钙盐的组合物及其制备方法
CN118652447B (zh) * 2024-08-19 2024-11-05 润美时光(北京)生物科技有限公司 一种胶原蛋白-透明质酸复合凝胶及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510418A (en) * 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
CA2140053C (en) * 1994-02-09 2000-04-04 Joel S. Rosenblatt Collagen-based injectable drug delivery system and its use
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
JP4187917B2 (ja) * 2000-09-08 2008-11-26 独立行政法人科学技術振興機構 組織再生マトリックス用グリコサミノグリカン−コラーゲン複合体の製造方法
US20060189516A1 (en) * 2002-02-19 2006-08-24 Industrial Technology Research Institute Method for producing cross-linked hyaluronic acid-protein bio-composites
JP3916516B2 (ja) * 2002-06-10 2007-05-16 独立行政法人科学技術振興機構 硬組織−軟組織界面再生用足場材料
BRPI0514349A (pt) * 2004-08-13 2008-06-10 Ottawa Health Research Inst dispositivos oftálmicos para o reforço da visão e métodos e composições relacionadas
US8697044B2 (en) * 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
US20130116411A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Methods of making hyaluronic acid/collagen compositions
JP6389820B2 (ja) 2012-09-06 2018-09-12 アラーガン、インコーポレイテッドAllergan,Incorporated ヒアルロン酸/コラーゲン系真皮充填剤組成物およびそれを作製するための方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107189119A (zh) * 2017-07-24 2017-09-22 苏州景卓生物技术有限公司 一种复合玻尿酸胶原蛋白水凝胶的制备方法及其应用
CN107189119B (zh) * 2017-07-24 2020-06-16 浙江景嘉医疗科技有限公司 一种复合玻尿酸胶原蛋白水凝胶的制备方法及其应用

Also Published As

Publication number Publication date
EP2892575A1 (en) 2015-07-15
JP6389820B2 (ja) 2018-09-12
JP7414687B2 (ja) 2024-01-16
EP3750568A1 (en) 2020-12-16
JP2015529268A (ja) 2015-10-05
WO2014039607A1 (en) 2014-03-13
EP2892575B1 (en) 2020-07-08
HK1212262A1 (en) 2016-06-10
JP2021027996A (ja) 2021-02-25

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20170906