CA2874229C - Sub-epidermal electric warning device - Google Patents
Sub-epidermal electric warning device Download PDFInfo
- Publication number
- CA2874229C CA2874229C CA2874229A CA2874229A CA2874229C CA 2874229 C CA2874229 C CA 2874229C CA 2874229 A CA2874229 A CA 2874229A CA 2874229 A CA2874229 A CA 2874229A CA 2874229 C CA2874229 C CA 2874229C
- Authority
- CA
- Canada
- Prior art keywords
- skin
- sub
- epidermal
- electric warning
- electrodes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000001519 tissue Anatomy 0.000 claims abstract description 10
- 210000002615 epidermis Anatomy 0.000 claims abstract description 9
- 230000000149 penetrating effect Effects 0.000 claims abstract description 7
- 239000012491 analyte Substances 0.000 claims abstract description 4
- 210000003491 skin Anatomy 0.000 claims description 113
- 239000012790 adhesive layer Substances 0.000 claims description 28
- 230000007246 mechanism Effects 0.000 claims description 28
- 238000003780 insertion Methods 0.000 claims description 25
- 230000037431 insertion Effects 0.000 claims description 25
- 239000012530 fluid Substances 0.000 claims description 7
- 238000007920 subcutaneous administration Methods 0.000 claims description 6
- 230000002159 abnormal effect Effects 0.000 claims description 4
- 230000004913 activation Effects 0.000 claims description 4
- 230000001070 adhesive effect Effects 0.000 claims description 4
- 239000010410 layer Substances 0.000 claims description 4
- 230000005856 abnormality Effects 0.000 claims description 3
- 239000000853 adhesive Substances 0.000 claims description 3
- 238000002347 injection Methods 0.000 claims description 3
- 239000007924 injection Substances 0.000 claims description 3
- 230000033764 rhythmic process Effects 0.000 claims description 2
- 239000003990 capacitor Substances 0.000 description 6
- 210000005036 nerve Anatomy 0.000 description 5
- 230000011664 signaling Effects 0.000 description 5
- 230000000638 stimulation Effects 0.000 description 5
- 230000007423 decrease Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 4
- 238000005562 fading Methods 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 238000005452 bending Methods 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 230000008447 perception Effects 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 230000035939 shock Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 241001631457 Cannula Species 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000006399 behavior Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000008058 pain sensation Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
- A61B5/6833—Adhesive patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6848—Needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6879—Means for maintaining contact with the body
- A61B5/688—Means for maintaining contact with the body using adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient; User input means
- A61B5/7455—Details of notification to user or communication with user or patient; User input means characterised by tactile indication, e.g. vibration or electrical stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0502—Skin piercing electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/24—Hygienic packaging for medical sensors; Maintaining apparatus for sensor hygiene
- A61B2562/242—Packaging, i.e. for packaging the sensor or apparatus before use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/70—General characteristics of the apparatus with testing or calibration facilities
- A61M2205/702—General characteristics of the apparatus with testing or calibration facilities automatically during use
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Optics & Photonics (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Electrotherapy Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12173390.1 | 2012-06-25 | ||
| EP12173390.1A EP2679154A1 (en) | 2012-06-25 | 2012-06-25 | Sub-epidermal electric warning device |
| PCT/EP2013/062180 WO2014001091A1 (en) | 2012-06-25 | 2013-06-12 | Sub-epidermal electric warning device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2874229A1 CA2874229A1 (en) | 2014-01-03 |
| CA2874229C true CA2874229C (en) | 2023-02-07 |
Family
ID=48699005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2874229A Active CA2874229C (en) | 2012-06-25 | 2013-06-12 | Sub-epidermal electric warning device |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10149974B2 (enExample) |
| EP (2) | EP2679154A1 (enExample) |
| JP (1) | JP6258929B2 (enExample) |
| KR (1) | KR102170537B1 (enExample) |
| CN (1) | CN104411240B (enExample) |
| CA (1) | CA2874229C (enExample) |
| DK (1) | DK2863797T3 (enExample) |
| ES (1) | ES2909739T3 (enExample) |
| IN (1) | IN2014KN02687A (enExample) |
| WO (1) | WO2014001091A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150289788A1 (en) * | 2014-04-10 | 2015-10-15 | Dexcom, Inc. | Sensors for continuous analyte monitoring, and related methods |
| CN108601562B (zh) * | 2016-02-05 | 2021-10-12 | 传感器健康公司 | 用于血液和/或组织液分析物的测量装置 |
| US20200254240A1 (en) * | 2016-05-15 | 2020-08-13 | Biolinq, Inc. | Devices and Methods For The Incorporation Of A Microneedle Array Analyte-Selective Sensor Into An Infusion Set, Patch Pump, Or Automated Therapeutic Delivery System |
| CN106725465A (zh) * | 2016-12-20 | 2017-05-31 | 杨洪 | 运动神经监测机构 |
| KR102200136B1 (ko) * | 2018-07-31 | 2021-01-11 | 주식회사 아이센스 | 연속 혈당 측정 장치 |
| WO2020219393A2 (en) | 2019-04-20 | 2020-10-29 | Biolark, Inc. | An infusion set having reduced patient pain |
| CN110115674B (zh) * | 2019-06-06 | 2021-06-22 | 南通大学附属医院 | 一种口腔术后恢复用智能咬合器 |
| KR102678960B1 (ko) * | 2021-08-26 | 2024-06-27 | 주식회사 에이피알 | 바디 관리기 |
| US20230233755A1 (en) * | 2022-01-21 | 2023-07-27 | Medtronic Minimed, Inc. | Ambulatory infusion pump device with integrated sensor |
| KR102877202B1 (ko) * | 2022-09-08 | 2025-10-29 | 주식회사 유엑스엔 | 록킹부를 구비한 연속식 분석물 측정기 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456012A (en) * | 1982-02-22 | 1984-06-26 | Medtronic, Inc. | Iontophoretic and electrical tissue stimulation device |
| CA2159052C (en) * | 1994-10-28 | 2007-03-06 | Rainer Alex | Injection device |
| TR199701414T1 (xx) | 1995-05-22 | 1998-02-21 | F. Hoffmann-La Roche Ag | Deriye yap��an t�bbi cihaz. |
| US6175763B1 (en) * | 1996-03-29 | 2001-01-16 | Alza Corporation | Electrotransport drug delivery device having tactile signaling means |
| WO2002015778A1 (en) | 2000-08-18 | 2002-02-28 | Cygnus, Inc. | Analyte monitoring device alarm augmentation system |
| US6560471B1 (en) * | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| CA2554232C (en) * | 2003-12-22 | 2013-07-09 | Paul Hadvary | Dermallly affixed sensor device |
| ATE384318T1 (de) | 2004-05-28 | 2008-02-15 | Geest Jan De | Kommunikationseinheit für die haut einer person |
| CN101102967A (zh) | 2004-09-14 | 2008-01-09 | 阿跨迪内股份有限公司 | 水蒸馏系统 |
| JP5399939B2 (ja) * | 2010-02-09 | 2014-01-29 | 大学共同利用機関法人自然科学研究機構 | 痛覚神経刺激装置 |
| EP2436311A1 (en) * | 2010-10-04 | 2012-04-04 | PharmaSens AG | Diagnostic device |
| EP2438938A1 (en) * | 2010-10-11 | 2012-04-11 | PharmaSens AG | Syringe type pump |
-
2012
- 2012-06-25 EP EP12173390.1A patent/EP2679154A1/en not_active Withdrawn
-
2013
- 2013-06-12 WO PCT/EP2013/062180 patent/WO2014001091A1/en not_active Ceased
- 2013-06-12 DK DK13731311.0T patent/DK2863797T3/da active
- 2013-06-12 CN CN201380033896.7A patent/CN104411240B/zh active Active
- 2013-06-12 ES ES13731311T patent/ES2909739T3/es active Active
- 2013-06-12 IN IN2687KON2014 patent/IN2014KN02687A/en unknown
- 2013-06-12 JP JP2015517682A patent/JP6258929B2/ja active Active
- 2013-06-12 CA CA2874229A patent/CA2874229C/en active Active
- 2013-06-12 US US14/408,075 patent/US10149974B2/en active Active
- 2013-06-12 KR KR1020157001920A patent/KR102170537B1/ko active Active
- 2013-06-12 EP EP13731311.0A patent/EP2863797B1/en active Active
-
2018
- 2018-07-20 US US16/041,159 patent/US20190022385A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2863797A1 (en) | 2015-04-29 |
| US20150174401A1 (en) | 2015-06-25 |
| KR102170537B1 (ko) | 2020-10-28 |
| ES2909739T3 (es) | 2022-05-10 |
| CA2874229A1 (en) | 2014-01-03 |
| US10149974B2 (en) | 2018-12-11 |
| EP2863797B1 (en) | 2022-01-26 |
| KR20150027811A (ko) | 2015-03-12 |
| EP2679154A1 (en) | 2014-01-01 |
| US20190022385A1 (en) | 2019-01-24 |
| CN104411240B (zh) | 2018-06-12 |
| WO2014001091A1 (en) | 2014-01-03 |
| JP6258929B2 (ja) | 2018-01-10 |
| DK2863797T3 (da) | 2022-04-11 |
| IN2014KN02687A (enExample) | 2015-05-08 |
| CN104411240A (zh) | 2015-03-11 |
| JP2015529472A (ja) | 2015-10-08 |
| HK1202403A1 (en) | 2015-10-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2874229C (en) | Sub-epidermal electric warning device | |
| US11033731B2 (en) | Methods and apparatuses for transdermal electrical stimulation | |
| CN101626793B (zh) | 利用电和振动刺激的表面麻醉 | |
| US9433785B2 (en) | Healing disc, a pain management assembly incorporating the disc, and a method of using the same | |
| US20050177201A1 (en) | Probe insertion pain reduction method and device | |
| AU2016215747A1 (en) | Venous electrical stimulation apparatus and methods and uses thereof | |
| WO2011133797A1 (en) | Topical analgesia using electrical and vibration stimuli | |
| US11045359B2 (en) | Nerve stimulation system | |
| US10092752B2 (en) | Venous electrical stimulation apparatus and methods and uses thereof | |
| HK1202403B (en) | Sub-epidermal electric warning device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20180316 |
|
| EEER | Examination request |
Effective date: 20180316 |
|
| EEER | Examination request |
Effective date: 20180316 |
|
| EEER | Examination request |
Effective date: 20180316 |
|
| EEER | Examination request |
Effective date: 20180316 |