CA2866502C - Derives de thiochromeno(2,3-c)quinolin-12-one, methode de preparation et application associees - Google Patents

Derives de thiochromeno(2,3-c)quinolin-12-one, methode de preparation et application associees Download PDF

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Publication number
CA2866502C
CA2866502C CA2866502A CA2866502A CA2866502C CA 2866502 C CA2866502 C CA 2866502C CA 2866502 A CA2866502 A CA 2866502A CA 2866502 A CA2866502 A CA 2866502A CA 2866502 C CA2866502 C CA 2866502C
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Canada
Prior art keywords
thiochromeno
quinolin
chloro
amino
compound
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Expired - Fee Related
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CA2866502A
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English (en)
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CA2866502A1 (fr
Inventor
Hsu-Shan Huang
Dah-Shyong Yu
Tsung-Chih Chen
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National Defense Medical Center
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National Defense Medical Center
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Priority to CA2866502A priority Critical patent/CA2866502C/fr
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Publication of CA2866502C publication Critical patent/CA2866502C/fr
Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Linvention présente une série de dérivés de thiochromeno[2,3-c] quinolin-12-one novateurs. De plus, linvention présente également la méthode de préparation et l'application desdits dérivés, ladite application comprenant la préparation desdits dérivés avec une quantité efficace de traitement en compositions pharmaceutiques en vue dempêcher la topoisomérase de types I et II, linhibition de la croissance de cellules cancéreuses, et de traiter le cancer.
CA2866502A 2014-10-03 2014-10-03 Derives de thiochromeno(2,3-c)quinolin-12-one, methode de preparation et application associees Expired - Fee Related CA2866502C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2866502A CA2866502C (fr) 2014-10-03 2014-10-03 Derives de thiochromeno(2,3-c)quinolin-12-one, methode de preparation et application associees

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2866502A CA2866502C (fr) 2014-10-03 2014-10-03 Derives de thiochromeno(2,3-c)quinolin-12-one, methode de preparation et application associees

Publications (2)

Publication Number Publication Date
CA2866502A1 CA2866502A1 (fr) 2016-04-03
CA2866502C true CA2866502C (fr) 2017-05-02

Family

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Family Applications (1)

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CA2866502A Expired - Fee Related CA2866502C (fr) 2014-10-03 2014-10-03 Derives de thiochromeno(2,3-c)quinolin-12-one, methode de preparation et application associees

Country Status (1)

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CA (1) CA2866502C (fr)

Also Published As

Publication number Publication date
CA2866502A1 (fr) 2016-04-03

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Effective date: 20211004