CA2865774A1 - Psma as a biomarker for androgen activity in prostate cancer - Google Patents

Psma as a biomarker for androgen activity in prostate cancer Download PDF

Info

Publication number
CA2865774A1
CA2865774A1 CA2865774A CA2865774A CA2865774A1 CA 2865774 A1 CA2865774 A1 CA 2865774A1 CA 2865774 A CA2865774 A CA 2865774A CA 2865774 A CA2865774 A CA 2865774A CA 2865774 A1 CA2865774 A1 CA 2865774A1
Authority
CA
Canada
Prior art keywords
psma
imaging
patient
prostate cancer
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2865774A
Other languages
English (en)
French (fr)
Inventor
Neil H. Bander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell University
Original Assignee
Cornell University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell University filed Critical Cornell University
Publication of CA2865774A1 publication Critical patent/CA2865774A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2865774A 2012-02-28 2013-02-27 Psma as a biomarker for androgen activity in prostate cancer Abandoned CA2865774A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261604039P 2012-02-28 2012-02-28
US61/604,039 2012-02-28
PCT/US2013/000051 WO2013130177A1 (en) 2012-02-28 2013-02-27 Psma as a biomarker for androgen activity in prostate cancer

Publications (1)

Publication Number Publication Date
CA2865774A1 true CA2865774A1 (en) 2013-09-06

Family

ID=49083148

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2865774A Abandoned CA2865774A1 (en) 2012-02-28 2013-02-27 Psma as a biomarker for androgen activity in prostate cancer

Country Status (6)

Country Link
US (1) US20130315830A1 (cg-RX-API-DMAC7.html)
EP (1) EP2819704A4 (cg-RX-API-DMAC7.html)
JP (1) JP2015508903A (cg-RX-API-DMAC7.html)
CA (1) CA2865774A1 (cg-RX-API-DMAC7.html)
HK (1) HK1202256A1 (cg-RX-API-DMAC7.html)
WO (1) WO2013130177A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150131208A (ko) 2013-03-13 2015-11-24 이미지냅 인코포레이티드 Cd8에의 항원 결합 구조체들
MX2018001566A (es) 2015-08-07 2019-04-25 Imaginab Inc Construcciones de union a antigeno para moleculas diana.
JP2020505034A (ja) 2017-01-20 2020-02-20 ジュノ セラピューティクス ゲーエムベーハー 細胞表面コンジュゲートならびに関連する細胞組成物および方法
AU2018250336B2 (en) 2017-04-07 2025-02-20 Juno Therapeutics, Inc. Engineered cells expressing prostate-specific membrane antigen (PSMA) or a modified form thereof and related methods
CA3113080A1 (en) * 2018-09-28 2020-04-02 Imaginab, Inc. Cd8 imaging constructs and methods of use thereof
WO2022114675A1 (ko) * 2020-11-24 2022-06-02 한국과학기술연구원 전립선암 진단을 위한 바이오마커, 이들의 조합, 및 이의 용도
EP4267969A4 (en) * 2020-12-22 2025-02-12 Mayo Foundation for Medical Education and Research METHODS AND MATERIALS FOR THE TREATMENT OF PROSTATE CANCER

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE337011T1 (de) * 2001-02-07 2006-09-15 Beth Israel Hospital Modifizierte psma-liganden und deren verwendung
AU2007227195A1 (en) * 2006-03-21 2007-09-27 The Regents Of The University Of California N-cadherin and Ly6 E: targets for cancer diagnosis and therapy
EP2209498A2 (en) * 2007-10-03 2010-07-28 Cornell University Treatment of proliferative disorders using antibodies to psma
US20100047166A1 (en) * 2008-08-20 2010-02-25 Kanner Steven B Antibodies and related molecules that bind to 58p1d12 proteins
EP2398504B1 (en) * 2009-02-17 2018-11-28 Cornell Research Foundation, Inc. Methods and kits for diagnosis of cancer and prediction of therapeutic value
EP4420730A3 (en) * 2009-03-19 2024-11-13 The Johns Hopkins University Psma-targeting compounds and uses thereof
WO2010119001A1 (en) * 2009-04-14 2010-10-21 Institut Gustave Roussy Prostate cancer cell lines and their use in screening method
EP2817629A4 (en) * 2012-02-24 2016-01-13 Univ Cornell INCREASED PSMA VALUE AS IDENTIFIER OF DEADLY PROSTATE CANCER

Also Published As

Publication number Publication date
US20130315830A1 (en) 2013-11-28
EP2819704A4 (en) 2015-10-21
JP2015508903A (ja) 2015-03-23
EP2819704A1 (en) 2015-01-07
HK1202256A1 (en) 2015-09-25
WO2013130177A1 (en) 2013-09-06

Similar Documents

Publication Publication Date Title
Chen et al. TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency
Yee et al. Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
US20130315830A1 (en) PSMA as a BioMarker for Androgen Activity in Prostate Cancer
Fu et al. Exosomal TRIM3 is a novel marker and therapy target for gastric cancer
Surowiak et al. ABCC2 (MRP2, cMOAT) can be localized in the nuclear membrane of ovarian carcinomas and correlates with resistance to cisplatin and clinical outcome
Cochrane et al. Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide
US20250230259A1 (en) Androgen suppression, prostate-specific membrane antigen and the concept of conditionally enhanced vulnerability
Nickkho-Amiry et al. Peroxisome proliferator–activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma
Makris et al. Quantitative changes in cytological molecular markers during primary medical treatment of breast cancer: a pilot study
Wang et al. Astrocyte elevated gene-1 is associated with metastasis in head and neck squamous cell carcinoma through p65 phosphorylation and upregulation of MMP1
Long et al. Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment, and on progression
Sammarco et al. Expression of the proto-oncogene c-KIT in normal and tumor tissues from colorectal carcinoma patients
Salehi et al. Biomarkers of pituitary neoplasms: a review (Part II)
AU2016270686A1 (en) Quantifying Her2 protein for optimal cancer therapy
Lopes et al. Anaplastic lymphoma kinase gene rearrangement in non-small-cell lung cancer in a Brazilian population
Gu et al. Overexpression of ADAMTS5 can regulate the migration and invasion of non-small cell lung cancer
Feng et al. Deubiquitinase USP10 promotes osteosarcoma autophagy and progression through regulating GSK3β-ULK1 axis
Chocarro-Calvo et al. Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression
Li et al. RACK1 overexpression associates with pancreatic ductal adenocarcinoma growth and poor prognosis
Lang et al. A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy
Gaber et al. Obesity increases DNA damage in the breast epithelium
Zhang et al. Secreted CLU is associated with the initiation of triple-negative breast cancer
US7718393B2 (en) Method for determining the efficacy of an anthracycline anticancer agent
Huang et al. Clinicopathological and cellular signature of PAK1 in human bladder cancer
WO2017172734A1 (en) Treating cancer metastasis

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180226

FZDE Discontinued

Effective date: 20210831