CA2794185C - Devices for injecting a substance and methods therefor - Google Patents
Devices for injecting a substance and methods therefor Download PDFInfo
- Publication number
- CA2794185C CA2794185C CA2794185A CA2794185A CA2794185C CA 2794185 C CA2794185 C CA 2794185C CA 2794185 A CA2794185 A CA 2794185A CA 2794185 A CA2794185 A CA 2794185A CA 2794185 C CA2794185 C CA 2794185C
- Authority
- CA
- Canada
- Prior art keywords
- housing
- needle
- plunger
- injection needle
- plunger base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000126 substance Substances 0.000 title description 11
- 238000000034 method Methods 0.000 title description 7
- 238000002347 injection Methods 0.000 claims abstract description 355
- 239000007924 injection Substances 0.000 claims abstract description 355
- 239000007788 liquid Substances 0.000 claims description 157
- 239000012530 fluid Substances 0.000 claims description 53
- 238000004891 communication Methods 0.000 claims description 47
- 238000002156 mixing Methods 0.000 claims description 21
- 238000010168 coupling process Methods 0.000 claims description 20
- 238000005859 coupling reaction Methods 0.000 claims description 20
- 230000008878 coupling Effects 0.000 claims description 15
- 239000006193 liquid solution Substances 0.000 claims description 14
- 238000011144 upstream manufacturing Methods 0.000 claims description 8
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 4
- 108010049003 Fibrinogen Proteins 0.000 description 4
- 102000008946 Fibrinogen Human genes 0.000 description 4
- 108090000190 Thrombin Proteins 0.000 description 4
- 229940012952 fibrinogen Drugs 0.000 description 4
- 229960004072 thrombin Drugs 0.000 description 4
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 229940102223 injectable solution Drugs 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000250 revascularization Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003106 tissue adhesive Substances 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/31581—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3257—Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M2005/3206—Needle or needle hub disconnecting devices forming part of or being attached to the hub or syringe body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Environmental & Geological Engineering (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31688110P | 2010-03-24 | 2010-03-24 | |
| US61/316,881 | 2010-03-24 | ||
| EP10250976A EP2389969A1 (en) | 2010-05-26 | 2010-05-26 | A device for injecting a substance |
| EP10250976.7 | 2010-05-26 | ||
| PCT/IL2011/000268 WO2011117867A2 (en) | 2010-03-24 | 2011-03-22 | Devices for injecting a substance and methods therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2794185A1 CA2794185A1 (en) | 2011-09-29 |
| CA2794185C true CA2794185C (en) | 2019-05-07 |
Family
ID=42989654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2794185A Expired - Fee Related CA2794185C (en) | 2010-03-24 | 2011-03-22 | Devices for injecting a substance and methods therefor |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9278181B2 (enExample) |
| EP (2) | EP2389969A1 (enExample) |
| JP (3) | JP5819396B2 (enExample) |
| AU (1) | AU2011231109B2 (enExample) |
| CA (1) | CA2794185C (enExample) |
| ES (1) | ES2557406T3 (enExample) |
| IL (1) | IL222009B (enExample) |
| WO (1) | WO2011117867A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7909789B2 (en) | 2006-06-26 | 2011-03-22 | Sight Sciences, Inc. | Intraocular implants and methods and kits therefor |
| US9022987B2 (en) * | 2008-07-07 | 2015-05-05 | Gabriel Institute, Inc. | Delivery system for injection through zone of body |
| US9808578B2 (en) | 2008-07-07 | 2017-11-07 | Gabriel Institute, Inc. | Delivery system for injections throughout zone of body |
| US8529516B2 (en) | 2008-07-07 | 2013-09-10 | Gabriel Institute, Inc. | Syringe for injection through zone of body |
| JP5856569B2 (ja) | 2010-02-05 | 2016-02-10 | サイト サイエンシーズ， インコーポレイテッド | 眼内圧を低減するためのデバイスと、それを含むキット |
| EP2389969A1 (en) * | 2010-05-26 | 2011-11-30 | Omrix Biopharmaceuticals Ltd. | A device for injecting a substance |
| EP2773309B1 (en) | 2011-10-31 | 2016-04-20 | GE Healthcare Limited | Pierce and fill device |
| ES2961369T3 (es) | 2012-03-20 | 2024-03-11 | Sight Sciences Inc | Sistemas de entrega ocular |
| WO2014204894A2 (en) | 2013-06-18 | 2014-12-24 | Enable Injections, Llc | Vial transfer and injection apparatus and method |
| EP2832390A1 (en) * | 2013-07-30 | 2015-02-04 | Sensile Pat AG | Drug delivery device with needle actuation mechanism |
| CA2920835A1 (en) | 2013-08-20 | 2015-02-26 | Anutra Medical, Inc. | Syringe fill system and method |
| JP6300940B2 (ja) * | 2014-01-30 | 2018-03-28 | メディカル・インジェクション・デヴァイシズ・インコーポレーテッド | 薬剤投与装置 |
| USD774182S1 (en) | 2014-06-06 | 2016-12-13 | Anutra Medical, Inc. | Anesthetic delivery device |
| USD763433S1 (en) * | 2014-06-06 | 2016-08-09 | Anutra Medical, Inc. | Delivery system cassette |
| US10299958B2 (en) | 2015-03-31 | 2019-05-28 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US11517527B2 (en) | 2018-11-05 | 2022-12-06 | Ethicon, Inc. | Systems, devices and methods for making and expressing foam used in medical procedures |
| ES3041526T3 (en) * | 2019-09-11 | 2025-11-12 | Lilly Co Eli | Medication delivery device with needle carrier |
| US11504270B1 (en) | 2019-09-27 | 2022-11-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3572336A (en) | 1968-04-30 | 1971-03-23 | Daniel R Hershberg | Syringe |
| US4026288A (en) * | 1975-10-21 | 1977-05-31 | Insulin Injector Inc. | Syringe injecting device |
| US4028288A (en) | 1976-02-03 | 1977-06-07 | Tire Recyclers International, Inc. | Moldable end products from primarily reclaimable waste materials |
| AT366916B (de) | 1980-04-02 | 1982-05-25 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen |
| DE3417757C2 (de) * | 1984-05-12 | 1994-11-10 | Lucas Dieter Dr | Injektionsspritze |
| US4609371A (en) | 1985-06-24 | 1986-09-02 | Pizzino Joanne L | Dual syringe for either simultaneous or sequential injection of liquids |
| DE59006067D1 (de) | 1989-11-21 | 1994-07-14 | Lindner Andreas Dr | Injektionsvorrichtung. |
| US5298023A (en) * | 1991-03-08 | 1994-03-29 | Habley Medical Technology Corporation | Multiple pharmaceutical dispenser with accumulator |
| US5749968A (en) * | 1993-03-01 | 1998-05-12 | Focal, Inc. | Device for priming for improved adherence of gels to substrates |
| US5478323A (en) | 1993-04-02 | 1995-12-26 | Eli Lilly And Company | Manifold for injection apparatus |
| JPH0767961A (ja) | 1993-07-09 | 1995-03-14 | Terumo Corp | 注射器 |
| US6783514B2 (en) | 1997-01-31 | 2004-08-31 | United States Surgical Corporation | Fibrin sealant applicator |
| CA2315802C (en) | 1997-12-19 | 2007-09-04 | United States Surgical Corporation | Two component dispenser system |
| US20040069044A1 (en) * | 1999-04-29 | 2004-04-15 | Gilad Lavi | Device for measuring a volume of drug |
| SE9901736D0 (sv) * | 1999-05-12 | 1999-05-12 | Pharmacia & Upjohn Ab | Injectino device and method for ITS operation |
| JP2004065737A (ja) | 2002-08-08 | 2004-03-04 | Nemoto Kyorindo:Kk | 薬液注入装置 |
| US20040064102A1 (en) | 2002-09-30 | 2004-04-01 | Akira Yamada | Double-barrel syringe for ophthalmic surgeries |
| US7641668B2 (en) * | 2003-05-16 | 2010-01-05 | Scimed Life Systems, Inc. | Fluid delivery system and related methods of use |
| US7632262B2 (en) | 2004-07-19 | 2009-12-15 | Nexeon Medical Systems, Inc. | Systems and methods for atraumatic implantation of bio-active agents |
| NZ560516A (en) * | 2005-02-01 | 2010-12-24 | Intelliject Inc | A delivery system where a medicant is automatically delivered on activation as well as a recorded instruction |
| CA2607756A1 (en) | 2005-05-16 | 2006-11-23 | Mallinckrodt Inc. | Multi-barrel syringe having integral manifold |
| US20090221914A1 (en) * | 2005-09-14 | 2009-09-03 | Acist Medical Systems, Inc. | Medical Fluid Injection System |
| DE602005013301D1 (de) | 2005-11-22 | 2009-04-23 | Omrix Biopharm Sa | Applikatorvorrichtung zum aufbringen einer mehrkomponenten-flüssigkeit |
| EP2214757A1 (en) * | 2007-11-22 | 2010-08-11 | Novo Nordisk Health Care AG | Medical mixing device |
| US8002736B2 (en) * | 2007-12-21 | 2011-08-23 | Carticept Medical, Inc. | Injection systems for delivery of fluids to joints |
| EP2389969A1 (en) * | 2010-05-26 | 2011-11-30 | Omrix Biopharmaceuticals Ltd. | A device for injecting a substance |
| US8568446B2 (en) * | 2010-05-13 | 2013-10-29 | Ethicon Endo-Surgery, Inc. | Multi-chamber therapeutic cell applicator instrument |
| US8491526B2 (en) * | 2010-05-13 | 2013-07-23 | Ethicon Endo-Surgery, Inc. | Therapeutic cell applicator instrument with modular tips |
-
2010
- 2010-05-26 EP EP10250976A patent/EP2389969A1/en not_active Withdrawn
-
2011
- 2011-03-22 US US13/053,448 patent/US9278181B2/en not_active Expired - Fee Related
- 2011-03-22 WO PCT/IL2011/000268 patent/WO2011117867A2/en not_active Ceased
- 2011-03-22 ES ES11716310.5T patent/ES2557406T3/es active Active
- 2011-03-22 CA CA2794185A patent/CA2794185C/en not_active Expired - Fee Related
- 2011-03-22 JP JP2013500655A patent/JP5819396B2/ja not_active Expired - Fee Related
- 2011-03-22 EP EP11716310.5A patent/EP2550048B1/en active Active
- 2011-03-22 AU AU2011231109A patent/AU2011231109B2/en not_active Ceased
-
2012
- 2012-09-20 IL IL222009A patent/IL222009B/en not_active IP Right Cessation
-
2015
- 2015-04-06 JP JP2015077523A patent/JP6087385B2/ja not_active Expired - Fee Related
-
2016
- 2016-01-27 US US15/007,346 patent/US10118002B2/en active Active
- 2016-07-05 JP JP2016133144A patent/JP6377677B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20160136360A1 (en) | 2016-05-19 |
| JP5819396B2 (ja) | 2015-11-24 |
| JP2016190068A (ja) | 2016-11-10 |
| WO2011117867A3 (en) | 2011-11-17 |
| WO2011117867A2 (en) | 2011-09-29 |
| EP2550048A2 (en) | 2013-01-30 |
| EP2389969A1 (en) | 2011-11-30 |
| CA2794185A1 (en) | 2011-09-29 |
| JP6087385B2 (ja) | 2017-03-01 |
| AU2011231109B2 (en) | 2016-02-25 |
| US20110238009A1 (en) | 2011-09-29 |
| ES2557406T3 (es) | 2016-01-25 |
| AU2011231109A1 (en) | 2012-10-25 |
| JP2013521972A (ja) | 2013-06-13 |
| JP2015163202A (ja) | 2015-09-10 |
| EP2550048B1 (en) | 2015-09-23 |
| IL222009B (en) | 2018-04-30 |
| US10118002B2 (en) | 2018-11-06 |
| US9278181B2 (en) | 2016-03-08 |
| JP6377677B2 (ja) | 2018-08-22 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20160310 |
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| MKLA | Lapsed |
Effective date: 20210322 |