CA2781049A1 - (poly)-glycerolphosphate-based anti-gram positive bacterial vaccine - Google Patents

(poly)-glycerolphosphate-based anti-gram positive bacterial vaccine Download PDF

Info

Publication number
CA2781049A1
CA2781049A1 CA2781049A CA2781049A CA2781049A1 CA 2781049 A1 CA2781049 A1 CA 2781049A1 CA 2781049 A CA2781049 A CA 2781049A CA 2781049 A CA2781049 A CA 2781049A CA 2781049 A1 CA2781049 A1 CA 2781049A1
Authority
CA
Canada
Prior art keywords
group
pgp
immunogenic composition
bacteria
glycerol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2781049A
Other languages
English (en)
French (fr)
Inventor
Clifford M. Snapper
Andrew Lees
James J. Mond
David Schwartz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henry M Jackson Foundation for Advancedment of Military Medicine Inc
Original Assignee
Henry M Jackson Foundation for Advancedment of Military Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henry M Jackson Foundation for Advancedment of Military Medicine Inc filed Critical Henry M Jackson Foundation for Advancedment of Military Medicine Inc
Publication of CA2781049A1 publication Critical patent/CA2781049A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2781049A 2009-11-16 2010-11-15 (poly)-glycerolphosphate-based anti-gram positive bacterial vaccine Abandoned CA2781049A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26157209P 2009-11-16 2009-11-16
US61/261,572 2009-11-16
PCT/US2010/056742 WO2011060379A2 (en) 2009-11-16 2010-11-15 (poly)-glycerolphosphate-based anti-gram positive bacterial vaccine

Publications (1)

Publication Number Publication Date
CA2781049A1 true CA2781049A1 (en) 2011-05-19

Family

ID=43992459

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2781049A Abandoned CA2781049A1 (en) 2009-11-16 2010-11-15 (poly)-glycerolphosphate-based anti-gram positive bacterial vaccine

Country Status (6)

Country Link
US (1) US20130052204A1 (https=)
EP (1) EP2501403A4 (https=)
JP (1) JP6091214B2 (https=)
AU (2) AU2010320031B2 (https=)
CA (1) CA2781049A1 (https=)
WO (1) WO2011060379A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10183237B2 (en) * 2014-03-21 2019-01-22 Biotage Ab Method and apparatus for the equilibration of a packed chromatography column
IL291323B2 (en) 2016-07-15 2023-09-01 Am Chemicals Llc Solid non-nucleoside supports and phosphoramidite building blocks for oligonucleotide synthesis
WO2025166099A1 (en) * 2024-02-02 2025-08-07 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Fire-retardant wood and wood composites, and compositions useful for making same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202219D0 (en) * 1992-02-03 1992-03-18 Connaught Lab A synthetic heamophilus influenzae conjugate vaccine
GB9808932D0 (en) * 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
GB9811347D0 (en) * 1998-05-28 1998-07-22 Oxoid Ltd Improvements in or relating diagnosis and treatment of bacterial infections
CA2391316A1 (en) * 2000-03-22 2001-09-27 Solulink, Incorporated Hydrazine-based and carbonyl-based bifunctional crosslinking reagents
AR046960A1 (es) * 2003-12-17 2006-01-04 Wyeth Corp Metodos para producir los conjugados portadores de peptidos inmunogenicos
WO2005072778A2 (en) * 2004-01-29 2005-08-11 Biosynexus, Inc. Use of amino-oxy functional groups in the preparation of vaccines conjugates
KR20070058631A (ko) * 2004-09-22 2007-06-08 글락소스미스클라인 바이오로지칼즈 에스.에이. 면역원성 조성물
US7754225B2 (en) * 2006-07-20 2010-07-13 Glaxosmithkline Biologicals S.A. Method of protecting against staphylococcal infection

Also Published As

Publication number Publication date
WO2011060379A3 (en) 2011-08-04
US20130052204A1 (en) 2013-02-28
JP6091214B2 (ja) 2017-03-08
EP2501403A4 (en) 2013-11-13
AU2015238927A1 (en) 2015-10-29
EP2501403A2 (en) 2012-09-26
AU2010320031A1 (en) 2012-06-14
AU2010320031B2 (en) 2015-07-16
JP2013510882A (ja) 2013-03-28
WO2011060379A2 (en) 2011-05-19

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20151019

FZDE Discontinued

Effective date: 20191029