CA2774621C - A method, an optical probe and a confocal microscopy system for inspecting a solid organ - Google Patents
A method, an optical probe and a confocal microscopy system for inspecting a solid organ Download PDFInfo
- Publication number
- CA2774621C CA2774621C CA2774621A CA2774621A CA2774621C CA 2774621 C CA2774621 C CA 2774621C CA 2774621 A CA2774621 A CA 2774621A CA 2774621 A CA2774621 A CA 2774621A CA 2774621 C CA2774621 C CA 2774621C
- Authority
- CA
- Canada
- Prior art keywords
- optical probe
- needle
- head
- ferule
- probe according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000523 sample Substances 0.000 title claims abstract description 94
- 230000003287 optical effect Effects 0.000 title claims abstract description 85
- 210000000056 organ Anatomy 0.000 title claims abstract description 79
- 239000007787 solid Substances 0.000 title claims abstract description 50
- 238000004624 confocal microscopy Methods 0.000 title claims description 10
- 238000000034 method Methods 0.000 title abstract description 20
- 239000013307 optical fiber Substances 0.000 claims abstract description 23
- 239000000835 fiber Substances 0.000 claims abstract description 15
- 238000002604 ultrasonography Methods 0.000 claims description 21
- 238000012800 visualization Methods 0.000 claims description 5
- 230000007246 mechanism Effects 0.000 claims description 4
- 230000002708 enhancing effect Effects 0.000 claims description 3
- 239000003292 glue Substances 0.000 claims description 3
- 238000003384 imaging method Methods 0.000 abstract description 5
- 230000003902 lesion Effects 0.000 description 12
- 210000000496 pancreas Anatomy 0.000 description 12
- 210000001519 tissue Anatomy 0.000 description 10
- 238000001839 endoscopy Methods 0.000 description 8
- 210000004185 liver Anatomy 0.000 description 8
- 238000003745 diagnosis Methods 0.000 description 7
- 210000001035 gastrointestinal tract Anatomy 0.000 description 5
- 210000001165 lymph node Anatomy 0.000 description 5
- 230000004323 axial length Effects 0.000 description 4
- 238000005286 illumination Methods 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
- 238000002591 computed tomography Methods 0.000 description 3
- 208000031513 cyst Diseases 0.000 description 3
- 210000001198 duodenum Anatomy 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000001574 biopsy Methods 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002440 hepatic effect Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 210000001672 ovary Anatomy 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 210000002307 prostate Anatomy 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 208000015634 Rectal Neoplasms Diseases 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000013276 bronchoscopy Methods 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 238000002574 cystoscopy Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000012336 endoscopic ultrasonography Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
- 238000002594 fluoroscopy Methods 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 238000010562 histological examination Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 238000002595 magnetic resonance imaging Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- 201000002528 pancreatic cancer Diseases 0.000 description 1
- 208000008443 pancreatic carcinoma Diseases 0.000 description 1
- 238000002600 positron emission tomography Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 206010038038 rectal cancer Diseases 0.000 description 1
- 201000001275 rectum cancer Diseases 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000005005 sentinel lymph node Anatomy 0.000 description 1
- 230000003393 splenic effect Effects 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0068—Confocal scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6848—Needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Endocrinology (AREA)
- Endoscopes (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
- Microscoopes, Condenser (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24342509P | 2009-09-17 | 2009-09-17 | |
| US61/243,425 | 2009-09-17 | ||
| PCT/IB2010/002653 WO2011033390A1 (en) | 2009-09-17 | 2010-09-17 | A method, an optical probe and a confocal microscopy system for inspecting a solid organ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2774621A1 CA2774621A1 (en) | 2011-03-24 |
| CA2774621C true CA2774621C (en) | 2017-07-11 |
Family
ID=43543774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2774621A Active CA2774621C (en) | 2009-09-17 | 2010-09-17 | A method, an optical probe and a confocal microscopy system for inspecting a solid organ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10722167B2 (enExample) |
| EP (1) | EP2477530B1 (enExample) |
| JP (1) | JP5721719B2 (enExample) |
| AU (1) | AU2010296946B2 (enExample) |
| CA (1) | CA2774621C (enExample) |
| ES (1) | ES2636767T3 (enExample) |
| WO (1) | WO2011033390A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014005048A2 (pt) | 2011-09-08 | 2017-06-13 | Koninklijke Philips Nv | dispositivo de agulha e agulha |
| CN104871024A (zh) * | 2012-12-18 | 2015-08-26 | 皇家飞利浦有限公司 | 用于表面和身体温度测量的可重复使用的mr 安全温度探头 |
| US8842273B2 (en) | 2013-02-14 | 2014-09-23 | United Sciences, Llc | Optical measurement of drilled holes |
| US10035009B2 (en) | 2013-04-15 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for treating pancreatic cancer |
| US9188775B2 (en) * | 2013-08-28 | 2015-11-17 | United Sciences, Llc | Optical scanning and measurement |
| JPWO2016051763A1 (ja) * | 2014-09-29 | 2017-08-03 | 富士フイルム株式会社 | 軟骨センシング装置 |
| CN104644110A (zh) * | 2015-02-06 | 2015-05-27 | 吉林大学 | 一种微型共聚焦激光显微内镜 |
| KR101898220B1 (ko) | 2015-08-04 | 2018-09-12 | 한국과학기술원 | 공초점 현미경 및 이를 이용한 영상 처리 방법 |
| CN109310296A (zh) | 2016-04-06 | 2019-02-05 | 爱丁堡大学董事会 | 内窥镜成像装置及方法 |
| GB201707239D0 (en) | 2017-05-05 | 2017-06-21 | Univ Edinburgh | Optical system and method |
| KR102114135B1 (ko) | 2019-02-28 | 2020-05-22 | 서강대학교산학협력단 | 현미경 장치 및 현미경 장치의 동작방법 |
| US12408815B2 (en) | 2021-03-31 | 2025-09-09 | Riken | Tomographic image processing device, tomographic image processing method, program, information recording medium, and puncture member |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH066131B2 (ja) * | 1989-01-11 | 1994-01-26 | 雅彦 星野 | レーザ治療器貝 |
| US4945895A (en) | 1989-03-20 | 1990-08-07 | Vance Products Incorporated | Remote fiber optic medical procedure and device |
| US6564087B1 (en) * | 1991-04-29 | 2003-05-13 | Massachusetts Institute Of Technology | Fiber optic needle probes for optical coherence tomography imaging |
| US5231684A (en) * | 1992-06-22 | 1993-07-27 | Pdt Systems | Optical fiber microlens |
| US5510895A (en) | 1993-03-05 | 1996-04-23 | Sahagen; Armen N. | Probe for monitoring a fluid medium |
| US6102905A (en) * | 1994-09-09 | 2000-08-15 | Cardiofocus, Inc. | Phototherapy device including housing for an optical element and method of making |
| EP0735391B1 (en) * | 1995-03-31 | 1998-12-30 | SEIKOH GIKEN Co., Ltd. | Optical fiber assembly and manufacturing method for the same |
| US5762637A (en) * | 1996-08-27 | 1998-06-09 | Scimed Life Systems, Inc. | Insert molded catheter tip |
| US5771327A (en) * | 1996-11-18 | 1998-06-23 | Optical Biopsy | Optical fiber probe protector |
| JP2000126115A (ja) | 1998-10-28 | 2000-05-09 | Olympus Optical Co Ltd | 光走査プローブ装置 |
| US6445939B1 (en) * | 1999-08-09 | 2002-09-03 | Lightlab Imaging, Llc | Ultra-small optical probes, imaging optics, and methods for using same |
| US6391020B1 (en) * | 1999-10-06 | 2002-05-21 | The Regents Of The Univerity Of Michigan | Photodisruptive laser nucleation and ultrasonically-driven cavitation of tissues and materials |
| US10595710B2 (en) * | 2001-10-19 | 2020-03-24 | Visionscope Technologies Llc | Portable imaging system employing a miniature endoscope |
| US6974557B1 (en) * | 2001-12-18 | 2005-12-13 | Advanced Cardiovasculer Systems, Inc. | Methods for forming an optical window for an intracorporeal device and for joining parts |
| EP2319405B1 (en) * | 2003-01-24 | 2013-09-18 | The General Hospital Corporation | System and method for identifying tissue using low-coherence interferometry |
| JP2004317437A (ja) * | 2003-04-18 | 2004-11-11 | Olympus Corp | 光イメージング装置 |
| JP4500619B2 (ja) | 2004-08-09 | 2010-07-14 | 株式会社トップ | 医療用コネクタ |
| JP5313507B2 (ja) * | 2005-02-15 | 2013-10-09 | アルコン，インコーポレイティド | 高スループットのエンドー照明器用プローブ |
| JP2006271874A (ja) | 2005-03-30 | 2006-10-12 | Toshiba Corp | 超音波ガイド下穿刺針 |
| US7492987B2 (en) * | 2005-12-19 | 2009-02-17 | Trimedyne, Inc. | Fiber optic laser energy delivery devices |
| WO2008008318A2 (en) | 2006-07-10 | 2008-01-17 | Boston Scientific Limited | Optical spectroscopic injection needle |
| WO2008081653A1 (ja) * | 2006-12-28 | 2008-07-10 | Terumo Kabushiki Kaisha | 光プローブ |
| US20080177257A1 (en) | 2007-01-23 | 2008-07-24 | Smith Ronald T | Thermally robust illumination probe tip |
| FR2913192B1 (fr) | 2007-03-02 | 2010-02-26 | Optical System & Res For Ind & Science Osyris | Ensemble canule/fibre optique et instrument laser comportant ledit ensemble. |
| US7952718B2 (en) | 2007-05-03 | 2011-05-31 | University Of Washington | High resolution optical coherence tomography based imaging for intraluminal and interstitial use implemented with a reduced form factor |
| US8603123B2 (en) * | 2008-04-28 | 2013-12-10 | Urotech, Inc. | Benign prostatic hyperplasia surgical system featuring mechanical coring probe with live aspiration |
| CN201987967U (zh) | 2008-06-27 | 2011-09-28 | 泰尔茂株式会社 | 留置针 |
| WO2010040142A1 (en) * | 2008-10-03 | 2010-04-08 | Lockheed Martin Corporation | Nerve stimulator and method using simultaneous electrical and optical signals |
-
2010
- 2010-09-17 US US13/496,526 patent/US10722167B2/en active Active
- 2010-09-17 ES ES10785187.5T patent/ES2636767T3/es active Active
- 2010-09-17 WO PCT/IB2010/002653 patent/WO2011033390A1/en not_active Ceased
- 2010-09-17 AU AU2010296946A patent/AU2010296946B2/en active Active
- 2010-09-17 CA CA2774621A patent/CA2774621C/en active Active
- 2010-09-17 JP JP2012529357A patent/JP5721719B2/ja active Active
- 2010-09-17 EP EP10785187.5A patent/EP2477530B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011033390A1 (en) | 2011-03-24 |
| US20120184842A1 (en) | 2012-07-19 |
| JP5721719B2 (ja) | 2015-05-20 |
| US10722167B2 (en) | 2020-07-28 |
| JP2013505043A (ja) | 2013-02-14 |
| EP2477530B1 (en) | 2017-05-10 |
| AU2010296946B2 (en) | 2015-08-06 |
| CA2774621A1 (en) | 2011-03-24 |
| AU2010296946A1 (en) | 2012-05-03 |
| ES2636767T3 (es) | 2017-10-09 |
| EP2477530A1 (en) | 2012-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130905 |