CA2758772A1 - Indole derivative modulators of the alpha 7 nachr - Google Patents
Indole derivative modulators of the alpha 7 nachr Download PDFInfo
- Publication number
- CA2758772A1 CA2758772A1 CA2758772A CA2758772A CA2758772A1 CA 2758772 A1 CA2758772 A1 CA 2758772A1 CA 2758772 A CA2758772 A CA 2758772A CA 2758772 A CA2758772 A CA 2758772A CA 2758772 A1 CA2758772 A1 CA 2758772A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- disorder
- trifluoromethyl
- methyl
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
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- Epidemiology (AREA)
- Psychology (AREA)
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- Child & Adolescent Psychology (AREA)
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- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16974209P | 2009-04-16 | 2009-04-16 | |
| US61/169,742 | 2009-04-16 | ||
| PCT/EP2010/054910 WO2010119078A1 (en) | 2009-04-16 | 2010-04-14 | Indole derivative modulators of the alpha 7 nachr |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2758772A1 true CA2758772A1 (en) | 2010-10-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2758772A Abandoned CA2758772A1 (en) | 2009-04-16 | 2010-04-14 | Indole derivative modulators of the alpha 7 nachr |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8829031B2 (https=) |
| EP (1) | EP2419420B1 (https=) |
| JP (1) | JP5642154B2 (https=) |
| KR (1) | KR20120089190A (https=) |
| CN (1) | CN102712622B (https=) |
| AU (1) | AU2010238518A1 (https=) |
| BR (1) | BRPI1014471A2 (https=) |
| CA (1) | CA2758772A1 (https=) |
| EA (1) | EA019518B1 (https=) |
| IL (1) | IL215551A (https=) |
| MX (1) | MX2011010734A (https=) |
| NZ (1) | NZ596390A (https=) |
| SG (1) | SG175084A1 (https=) |
| WO (1) | WO2010119078A1 (https=) |
| ZA (1) | ZA201107988B (https=) |
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| NZ596390A (en) * | 2009-04-16 | 2013-08-30 | Proximagen Ltd | Indole derivative modulators of the alpha 7 nachr |
| GB201012686D0 (en) * | 2010-07-28 | 2010-09-15 | Glaxo Group Ltd | Novel compounds |
| TW201245185A (en) | 2011-04-01 | 2012-11-16 | Lundbeck & Co As H | New positive allosteric modulators of nicotinic acetylcholine receptor |
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| SE9903997D0 (sv) * | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
| US20040242559A1 (en) * | 2003-04-25 | 2004-12-02 | Aventis Pharma S.A. | Novel indole derivatives, preparation thereof as medicinal products and pharmaceutical compositions, and especially as KDR inhibitors |
| GB0403155D0 (en) * | 2004-02-12 | 2004-03-17 | Vernalis Res Ltd | Chemical compounds |
| US8410142B2 (en) * | 2007-03-02 | 2013-04-02 | Merck Sharp & Dohme Corp. | Bipyridine carboxamide orexin receptor antagonists |
| KR20100124272A (ko) * | 2008-02-07 | 2010-11-26 | 아보트 러보러터리즈 | 양성 알로스테릭 조절제로서의 아미드 유도체 및 이의 사용방법 |
| WO2009127678A1 (en) * | 2008-04-17 | 2009-10-22 | Glaxo Group Limited | Indoles as modulators of nicotinic acetylcholin receptor subtype alpha-71 |
| NZ596390A (en) * | 2009-04-16 | 2013-08-30 | Proximagen Ltd | Indole derivative modulators of the alpha 7 nachr |
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2010
- 2010-04-14 NZ NZ596390A patent/NZ596390A/xx not_active IP Right Cessation
- 2010-04-14 AU AU2010238518A patent/AU2010238518A1/en not_active Abandoned
- 2010-04-14 WO PCT/EP2010/054910 patent/WO2010119078A1/en not_active Ceased
- 2010-04-14 CN CN201080024640.6A patent/CN102712622B/zh not_active Expired - Fee Related
- 2010-04-14 KR KR1020117027026A patent/KR20120089190A/ko not_active Ceased
- 2010-04-14 US US13/263,370 patent/US8829031B2/en not_active Expired - Fee Related
- 2010-04-14 MX MX2011010734A patent/MX2011010734A/es active IP Right Grant
- 2010-04-14 SG SG2011072683A patent/SG175084A1/en unknown
- 2010-04-14 EP EP10713943A patent/EP2419420B1/en not_active Not-in-force
- 2010-04-14 EA EA201101325A patent/EA019518B1/ru not_active IP Right Cessation
- 2010-04-14 JP JP2012505160A patent/JP5642154B2/ja not_active Expired - Fee Related
- 2010-04-14 CA CA2758772A patent/CA2758772A1/en not_active Abandoned
- 2010-04-14 BR BRPI1014471A patent/BRPI1014471A2/pt not_active IP Right Cessation
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2011
- 2011-10-05 IL IL215551A patent/IL215551A/en not_active IP Right Cessation
- 2011-11-01 ZA ZA2011/07988A patent/ZA201107988B/en unknown
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2014
- 2014-08-07 US US14/453,816 patent/US20150038517A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5642154B2 (ja) | 2014-12-17 |
| EP2419420B1 (en) | 2013-03-13 |
| IL215551A (en) | 2014-07-31 |
| BRPI1014471A2 (pt) | 2016-04-05 |
| WO2010119078A1 (en) | 2010-10-21 |
| EA019518B1 (ru) | 2014-04-30 |
| ZA201107988B (en) | 2012-07-25 |
| CN102712622B (zh) | 2014-05-07 |
| MX2011010734A (es) | 2011-12-06 |
| NZ596390A (en) | 2013-08-30 |
| SG175084A1 (en) | 2011-11-28 |
| CN102712622A (zh) | 2012-10-03 |
| KR20120089190A (ko) | 2012-08-09 |
| EA201101325A1 (ru) | 2012-05-30 |
| EP2419420A1 (en) | 2012-02-22 |
| AU2010238518A1 (en) | 2011-12-01 |
| IL215551A0 (en) | 2011-12-29 |
| JP2012524043A (ja) | 2012-10-11 |
| WO2010119078A9 (en) | 2011-02-03 |
| US20150038517A1 (en) | 2015-02-05 |
| US8829031B2 (en) | 2014-09-09 |
| US20120136009A1 (en) | 2012-05-31 |
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| AU2011322562B2 (en) | Alpha-7 nicotinic receptor modulators for the treatment of pain, a psychotic disorder, cognitive impairment or Alzheimer's disease | |
| EP2488514B1 (en) | Indole and azaindole modulators of the alpha 7 nachr | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20150325 |
|
| FZDE | Discontinued |
Effective date: 20170418 |