CA2755245A1 - Compositions and methods for the delivery of biologically active rnas - Google Patents
Compositions and methods for the delivery of biologically active rnas Download PDFInfo
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- CA2755245A1 CA2755245A1 CA2755245A CA2755245A CA2755245A1 CA 2755245 A1 CA2755245 A1 CA 2755245A1 CA 2755245 A CA2755245 A CA 2755245A CA 2755245 A CA2755245 A CA 2755245A CA 2755245 A1 CA2755245 A1 CA 2755245A1
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| RU2648950C2 (ru) | 2011-10-03 | 2018-04-02 | Модерна Терапьютикс, Инк. | Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение |
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| KR20140123054A (ko) * | 2011-12-23 | 2014-10-21 | 씨엘에스엔 래버러토리스, 인코퍼레이티드 | 생물학적 활성 ｒｎａ의 전달을 위한 조성물 및 방법 |
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| HRP20220607T1 (hr) | 2012-11-26 | 2022-06-24 | Modernatx, Inc. | Terminalno modificirana rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| KR20160021076A (ko) * | 2013-03-15 | 2016-02-24 | 테출론 인코포레이티드 | 스타필로코커스 아우레우스 감염의 치료를 위한 안티센스 분자 |
| WO2015002956A1 (en) * | 2013-07-01 | 2015-01-08 | Ohio State Innovation Foundation | Exosome delivery system |
| AU2014292926B2 (en) | 2013-07-25 | 2020-03-05 | Exicure Operating Company | Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use |
| WO2015023797A1 (en) | 2013-08-13 | 2015-02-19 | Northwestern University | Lipophilic nanoparticles for drug delivery |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
| EP3184641B1 (en) | 2013-10-28 | 2020-07-08 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Oncolytic hsv vector |
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| EP3183007B1 (en) | 2014-08-19 | 2020-06-17 | Northwestern University | Protein/oligonucleotide core-shell nanoparticle therapeutics |
| EA201790802A1 (ru) | 2014-10-06 | 2017-08-31 | Экзикьюр, Инк. | Соединения против tnf |
| US9816080B2 (en) * | 2014-10-31 | 2017-11-14 | President And Fellows Of Harvard College | Delivery of CAS9 via ARRDC1-mediated microvesicles (ARMMs) |
| US10078092B2 (en) | 2015-03-18 | 2018-09-18 | Northwestern University | Assays for measuring binding kinetics and binding capacity of acceptors for lipophilic or amphiphilic molecules |
| RU2021114137A (ru) | 2016-01-27 | 2021-05-25 | Онкорус, Инк. | Онколитические вирусные векторы и их применение |
| US11639371B2 (en) * | 2016-02-17 | 2023-05-02 | The Chinese University Of Hong Kong | Peptidylic inhibitors of nucleolin (NCL) targeting CAG-repeat RNA toxicity and methods for reducing polyQ-mediated toxicity in polyQ diseases |
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| US20050074865A1 (en) * | 2002-08-27 | 2005-04-07 | Compound Therapeutics, Inc. | Adzymes and uses thereof |
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-
2010
- 2010-03-15 CA CA2755245A patent/CA2755245A1/en not_active Abandoned
- 2010-03-15 EP EP10751551A patent/EP2406379A4/en not_active Withdrawn
- 2010-03-15 CN CN2010800210226A patent/CN102625842A/zh active Pending
- 2010-03-15 KR KR1020117024110A patent/KR20110128345A/ko not_active Ceased
- 2010-03-15 AU AU2010223888A patent/AU2010223888A1/en not_active Abandoned
- 2010-03-15 JP JP2011554275A patent/JP2012520085A/ja active Pending
- 2010-03-15 US US12/724,408 patent/US8569065B2/en active Active
- 2010-03-15 WO PCT/US2010/027365 patent/WO2010105277A1/en not_active Ceased
-
2013
- 2013-03-11 US US13/793,961 patent/US20140005254A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20110128345A (ko) | 2011-11-29 |
| US20140005254A1 (en) | 2014-01-02 |
| AU2010223888A1 (en) | 2011-10-06 |
| EP2406379A1 (en) | 2012-01-18 |
| WO2010105277A1 (en) | 2010-09-16 |
| US20100233141A1 (en) | 2010-09-16 |
| US8569065B2 (en) | 2013-10-29 |
| EP2406379A4 (en) | 2012-09-26 |
| JP2012520085A (ja) | 2012-09-06 |
| CN102625842A (zh) | 2012-08-01 |
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