CA2745077A1 - Injection device with holding means to prevent unintentional movements of piston rod - Google Patents

Injection device with holding means to prevent unintentional movements of piston rod Download PDF

Info

Publication number
CA2745077A1
CA2745077A1 CA2745077A CA2745077A CA2745077A1 CA 2745077 A1 CA2745077 A1 CA 2745077A1 CA 2745077 A CA2745077 A CA 2745077A CA 2745077 A CA2745077 A CA 2745077A CA 2745077 A1 CA2745077 A1 CA 2745077A1
Authority
CA
Canada
Prior art keywords
piston rod
housing
injection
holding means
injection device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2745077A
Other languages
English (en)
French (fr)
Inventor
Michael Schabbach
Axel Roth
Gerhard Hambrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41017119&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2745077(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CA2745077A1 publication Critical patent/CA2745077A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485—Ampoule holder connected to rest of syringe
    • A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/3151—Means for blocking or restricting the movement of the rod or piston by friction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CA2745077A 2008-12-04 2009-12-01 Injection device with holding means to prevent unintentional movements of piston rod Abandoned CA2745077A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08021046.1 2008-12-04
EP08021046 2008-12-04
PCT/EP2009/066094 WO2010063687A1 (en) 2008-12-04 2009-12-01 Injection device with holding means to prevent unintentional movements of piston rod

Publications (1)

Publication Number Publication Date
CA2745077A1 true CA2745077A1 (en) 2010-06-10

Family

ID=41017119

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2745077A Abandoned CA2745077A1 (en) 2008-12-04 2009-12-01 Injection device with holding means to prevent unintentional movements of piston rod

Country Status (22)

Country Link
US (3) US8915881B2 (OSRAM)
EP (1) EP2373362B1 (OSRAM)
JP (1) JP5622743B2 (OSRAM)
KR (1) KR101677068B1 (OSRAM)
CN (1) CN102238974B (OSRAM)
AU (1) AU2009324174B2 (OSRAM)
BR (1) BRPI0922692B8 (OSRAM)
CA (1) CA2745077A1 (OSRAM)
DK (1) DK2373362T3 (OSRAM)
ES (1) ES2648867T3 (OSRAM)
HU (1) HUE035759T2 (OSRAM)
IL (1) IL213327A (OSRAM)
MX (1) MX2011004660A (OSRAM)
MY (1) MY154862A (OSRAM)
NO (1) NO2373362T3 (OSRAM)
NZ (1) NZ593248A (OSRAM)
PL (1) PL2373362T3 (OSRAM)
RU (1) RU2526438C2 (OSRAM)
SG (1) SG171946A1 (OSRAM)
TW (1) TWI522138B (OSRAM)
WO (1) WO2010063687A1 (OSRAM)
ZA (1) ZA201102842B (OSRAM)

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WO2011097742A1 (de) * 2010-02-12 2011-08-18 Medmix Systems Ag Austragvorrichtung mit rastelement
BR112013008617A2 (pt) * 2010-10-13 2016-06-14 Sanofi Aventis Deutschland mecanismo de ajuste de dose e método de uso do mesmo
WO2013007769A1 (en) * 2011-07-14 2013-01-17 Sanofi-Aventis Deutschland Gmbh Drive mechanism of a drug delivery device
AR088689A1 (es) * 2011-11-09 2014-06-25 Sanofi Aventis Deutschland Conjunto de accionamiento para un dispositivo de administracion de medicacion y un dispositivo de administracion de medicacion que comprende un conjunto de accionamiento
EP2788047A1 (en) * 2011-12-06 2014-10-15 Novo Nordisk A/S A drive mechanism for an injection device and a method of assembling an injection device incorporating such drive mechanism
JP6214549B2 (ja) * 2011-12-08 2017-10-18 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 薬剤送達デバイス用の駆動アセンブリおよび駆動アセンブリを備える薬剤送達デバイス
US10328211B2 (en) 2011-12-08 2019-06-25 Unl Holdings Llc Automatic self-dispensing accurate dose drug delivery syringes
US10213556B2 (en) 2011-12-08 2019-02-26 Unl Holdings Llc Accurate dose control mechanisms and drug delivery syringes
RU2650207C2 (ru) * 2011-12-08 2018-04-11 Юнитрект Сириндж Пти Лтд Механизм контроля точной величины дозы и шприц для доставки лекарства
DE102013007389A1 (de) * 2013-04-30 2014-10-30 Britannia Pharmaceuticals Ltd. Medikamentenverabreichungsvorrichtung
CN103467268B (zh) * 2013-09-26 2015-03-25 山东午阳化工股份有限公司 一种2,2′-二羟基-4,4′-二甲氧基二苯甲酮的制备方法
CN103637856B (zh) * 2013-11-14 2015-09-09 燕海峰 单手直压式连续定量吸排液器
GB2529621B (en) * 2014-08-21 2016-12-07 Owen Mumford Ltd Safety syringe
WO2016174213A1 (en) * 2015-04-29 2016-11-03 Novo Nordisk A/S Drug delivery device with spring mechanism
EP3181170A1 (en) 2015-12-14 2017-06-21 Sanofi-Aventis Deutschland GmbH Drive mechanism for an injection device
CN105727400B (zh) * 2016-02-03 2023-02-17 苏州翰尔西医疗器械开发有限公司 给药装置
WO2017180480A1 (en) * 2016-04-15 2017-10-19 Santen Pharmaceuticals Co., Ltd. Accurate, precise microliter dosing syringe
US11331435B2 (en) 2016-05-27 2022-05-17 Shl Medical Ag Actuation mechanism
WO2018085451A1 (en) 2016-11-01 2018-05-11 Credence Medsystems, Inc. Safety syringe
EP3609559B1 (en) * 2017-04-13 2022-08-17 Becton, Dickinson and Company Controlled delivery syringe device
FR3072297B1 (fr) * 2017-10-17 2023-05-12 Edix Sa Dispositif d'injection manuelle
EP3773810B1 (en) 2018-03-27 2024-08-28 SHL Medical AG Drive mechanism and medicament delivery device comprising the same
CN109172952B (zh) * 2018-10-08 2023-09-26 东曜药业有限公司 注射器以及用于注射器的辅助定量装置
JP7779833B2 (ja) 2019-11-14 2025-12-03 コングルーエンス メディカル ソリューションズ，エルエルシー 可変投薬注射器
CN116328102B (zh) * 2023-05-31 2023-08-01 四川省医学科学院·四川省人民医院 一种糖尿病用注射装置
CN117018350A (zh) * 2023-08-04 2023-11-10 肯多科技(浙江)有限公司 一种笔式注射器
CN120361358B (zh) * 2025-06-30 2025-10-10 苏州嘉树医疗科技有限公司 一种注射装置的剂量调节机构和注射装置
CN120381582B (zh) * 2025-06-30 2025-10-03 苏州嘉树医疗科技有限公司 一种注射装置的剂量调节机构和注射装置

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GB551545A (en) * 1942-01-13 1943-02-26 Samuel James Everett Improvements in or relating to hypodermic and like syringes
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JPH0611337B2 (ja) * 1991-02-07 1994-02-16 イーライ・リリー・アンド・カンパニー 注射器及び投薬量調整装置
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DE29900482U1 (de) 1999-01-14 2000-08-31 Medico Development Investment Co., Ascona Injektionsgerät
GB0007071D0 (en) * 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
DE10163327A1 (de) * 2001-07-30 2003-02-27 Disetronic Licensing Ag Reservoirmodul mit Kolbenstange
DE20112501U1 (de) * 2001-07-30 2002-12-19 Disetronic Licensing Ag, Burgdorf Verriegelungssperre für eine Verbindung von Gehäuseteilen eines Injektions- oder Infusionsgeräts
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Also Published As

Publication number Publication date
HUE035759T2 (en) 2018-05-28
MY154862A (en) 2015-08-14
BRPI0922692A2 (pt) 2016-01-05
EP2373362A1 (en) 2011-10-12
US20150165131A1 (en) 2015-06-18
TWI522138B (zh) 2016-02-21
SG171946A1 (en) 2011-07-28
BRPI0922692B8 (pt) 2021-06-22
PL2373362T3 (pl) 2018-03-30
JP5622743B2 (ja) 2014-11-12
NO2373362T3 (OSRAM) 2018-03-10
KR20110096537A (ko) 2011-08-30
RU2011127107A (ru) 2013-01-10
IL213327A0 (en) 2011-07-31
TW201036659A (en) 2010-10-16
US9415170B2 (en) 2016-08-16
MX2011004660A (es) 2011-05-30
DK2373362T3 (en) 2018-01-15
ES2648867T8 (es) 2019-02-15
HK1158995A1 (en) 2012-07-27
BRPI0922692B1 (pt) 2020-08-25
ZA201102842B (en) 2011-12-28
US8915881B2 (en) 2014-12-23
IL213327A (en) 2015-06-30
AU2009324174A1 (en) 2011-06-23
KR101677068B1 (ko) 2016-11-29
US20150141933A1 (en) 2015-05-21
EP2373362B1 (en) 2017-10-11
US20120095412A1 (en) 2012-04-19
NZ593248A (en) 2013-12-20
JP2012510836A (ja) 2012-05-17
CN102238974B (zh) 2014-09-03
RU2526438C2 (ru) 2014-08-20
AU2009324174B2 (en) 2014-07-31
ES2648867T3 (es) 2018-01-08
WO2010063687A1 (en) 2010-06-10
CN102238974A (zh) 2011-11-09

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