CA2743590A1 - Diagnosis of multiple sclerosis - Google Patents

Diagnosis of multiple sclerosis Download PDF

Info

Publication number
CA2743590A1
CA2743590A1 CA2743590A CA2743590A CA2743590A1 CA 2743590 A1 CA2743590 A1 CA 2743590A1 CA 2743590 A CA2743590 A CA 2743590A CA 2743590 A CA2743590 A CA 2743590A CA 2743590 A1 CA2743590 A1 CA 2743590A1
Authority
CA
Canada
Prior art keywords
antigens
pattern
listed
reactivity
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2743590A
Other languages
English (en)
French (fr)
Inventor
Howard L. Weiner
Irun R. Cohen
Francisco J. Quintana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Brigham and Womens Hospital Inc
Original Assignee
Yeda Research and Development Co Ltd
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd, Brigham and Womens Hospital Inc filed Critical Yeda Research and Development Co Ltd
Publication of CA2743590A1 publication Critical patent/CA2743590A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/285—Demyelinating diseases; Multipel sclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2743590A 2008-11-12 2009-11-12 Diagnosis of multiple sclerosis Abandoned CA2743590A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11364508P 2008-11-12 2008-11-12
US61/113,645 2008-11-12
PCT/IL2009/001066 WO2010055510A2 (en) 2008-11-12 2009-11-12 Diagnosis of multiple sclerosis

Publications (1)

Publication Number Publication Date
CA2743590A1 true CA2743590A1 (en) 2010-05-20

Family

ID=42170484

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2743590A Abandoned CA2743590A1 (en) 2008-11-12 2009-11-12 Diagnosis of multiple sclerosis

Country Status (7)

Country Link
US (1) US9267945B2 (cg-RX-API-DMAC7.html)
EP (1) EP2353004B1 (cg-RX-API-DMAC7.html)
JP (1) JP2012508865A (cg-RX-API-DMAC7.html)
CN (1) CN102388307B (cg-RX-API-DMAC7.html)
AU (1) AU2009315230A1 (cg-RX-API-DMAC7.html)
CA (1) CA2743590A1 (cg-RX-API-DMAC7.html)
WO (1) WO2010055510A2 (cg-RX-API-DMAC7.html)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140105980A1 (en) 2012-10-11 2014-04-17 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
US20190263888A1 (en) 2010-10-19 2019-08-29 Op-T Llc Therapeutic peptides and methods for treating autoimmune related disease
EP3421487B1 (en) 2010-10-19 2023-06-28 The Regents of the University of Colorado, a body corporate Peptides for modulating t-cell activity and uses thereof
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US8652999B1 (en) 2012-07-24 2014-02-18 Dow Agrosciences, Llc. Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
GB201300684D0 (en) 2013-01-15 2013-02-27 Apitope Int Nv Peptide
CN105899229A (zh) 2013-11-04 2016-08-24 Uti有限合伙公司 用于持续的免疫治疗的方法和组合物
CA2933554A1 (en) * 2013-12-12 2015-06-18 The Brigham And Women's Hospital, Inc. Treating neurodegenerative disease
WO2015101988A1 (en) 2013-12-31 2015-07-09 Yeda Research And Development Co. Ltd. Diagnosis of systemic lupus erythematosus using oligonucleotides antigens
EP3090263A4 (en) 2013-12-31 2017-08-23 Yeda Research and Development Co., Ltd. Methods for assaying immunological competence
WO2015148389A2 (en) * 2014-03-23 2015-10-01 The Regents Of The University Of Colorado Diagnosis of multiple sclerosis in human and animal subjects
EP2927687A1 (en) * 2014-03-31 2015-10-07 Ecole Polytechnique Federale de Lausanne (EPFL) Agents useful in diagnostic and therapy of beta-amyloid aggregation related disorders and screening methods
WO2015172008A1 (en) * 2014-05-09 2015-11-12 Multiple Sclerosis Research Center Of New York Transglutaminadase 6 as a biomarker for multiple sclerosis
WO2016123565A1 (en) 2015-01-30 2016-08-04 The Regents Of The University Of California N-acetyl glucosamine as a biomarker of ms disease course
WO2016139659A1 (en) 2015-03-01 2016-09-09 Immunarray Ltd. Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens
WO2016198932A2 (en) 2015-05-06 2016-12-15 Uti Limited Partnership Nanoparticle compositions for sustained therapy
CN107043413A (zh) * 2016-02-05 2017-08-15 华中农业大学 一种肺结核相关的尿液生物标志蛋白及其应用
WO2018048884A1 (en) * 2016-09-09 2018-03-15 Mayo Foundation For Medical Education And Research Methods and materials for identifying and treating autoimmune gfap astrocytopathy
DK3538559T3 (da) 2016-11-09 2025-07-14 Uti Lp Rekombinante pmhc klasse ii-molekyler
AU2018248961B2 (en) 2017-04-07 2024-06-20 Uti Limited Partnership Assay to measure the potency of receptor-ligand interactions in nanomedicines
CN111741746A (zh) 2017-11-29 2020-10-02 乌第有限合伙公司 治疗自身免疫性疾病的方法
US11793854B2 (en) 2019-03-21 2023-10-24 Op-T Llc Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction
US12048734B2 (en) 2020-04-17 2024-07-30 Op-T Llc Bioactive peptides and methods of use thereof
CN114689865A (zh) * 2020-12-30 2022-07-01 广州市微米生物科技有限公司 视神经脊髓炎抗体检测试剂
CN113336862B (zh) * 2021-07-05 2022-03-01 广东省科学院动物研究所 一种抗多发性硬化的重组蛋白及其制备方法和用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL137460A0 (en) 2000-07-24 2001-07-24 Yeda Res & Dev Identifying antigen clusters for monitoring a global state of an immune system
EP1351707B9 (en) * 2001-01-09 2012-01-25 Baylor Research Institute Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays
EP1386155A4 (en) 2001-04-10 2006-05-10 Univ Leland Stanford Junior THERAPEUTIC AND DIAGNOSTIC USE OF ANTIBODY SPECIFICITY PROFILES
US20030092089A1 (en) 2001-11-14 2003-05-15 Moscarello Mario Anthony Method for diagnosing multiple sclerosis and an assay therefore
IL148401A0 (en) 2002-02-26 2002-09-12 Hadasit Med Res Service Hsp70-derived peptides and uses thereof in the diagnosis and treatment of autoimmune diseases
US20050009096A1 (en) 2002-10-11 2005-01-13 The Regents Of The University Of California Method for diagnosis and prognosis of multiple sclerosis
US20050260770A1 (en) 2004-04-01 2005-11-24 Cohen Irun R Antigen array and diagnostic uses thereof
EA200700263A1 (ru) 2004-07-01 2007-06-29 Кебенхавнс Университет Способ лечения и профилактики рассеянного склероза путём лечения лептоспирозной инфекции
US20080194711A1 (en) * 2005-01-19 2008-08-14 Frauke Zipp-Nitsch Cx3Cr1 As A Marker Which Correlates With Both Disease And Disease Activity In Multiple Sclerosis Patients
US7572592B2 (en) 2005-01-31 2009-08-11 Glycominds Ltd Method for diagnosing multiple sclerosis
JP2008532936A (ja) 2005-02-14 2008-08-21 ワイス インターロイキン−１７ｆ抗体及び他のｉｌ−１７ｆシグナル伝達拮抗物質並びにそれらの使用
WO2006116155A2 (en) * 2005-04-21 2006-11-02 The Regents Of The University Of California A method for diagnosis and prognosis of multiple sclerosis subtypes
WO2007014001A2 (en) * 2005-07-21 2007-02-01 The Board Of Trustees Of The Leland Stanford Junior University Multiplex determination of lipid specific binding moieties
WO2007056332A2 (en) * 2005-11-07 2007-05-18 Vanderbilt University Molecular diagnosis of autoimmune diseases
AU2007266218C1 (en) 2006-05-26 2013-05-23 Phenomenome Discoveries Inc. Biomarkers for diagnosing multiple sclerosis, and methods thereof
CN101680883A (zh) * 2007-04-12 2010-03-24 艾匹托普国际股份有限公司 用于多发性硬化的生物标记

Also Published As

Publication number Publication date
WO2010055510A2 (en) 2010-05-20
CN102388307B (zh) 2014-09-03
US20120077686A1 (en) 2012-03-29
EP2353004B1 (en) 2018-01-03
JP2012508865A (ja) 2012-04-12
EP2353004A4 (en) 2012-04-18
EP2353004A2 (en) 2011-08-10
HK1168423A1 (en) 2012-12-28
CN102388307A (zh) 2012-03-21
AU2009315230A1 (en) 2010-05-20
WO2010055510A3 (en) 2010-09-16
US9267945B2 (en) 2016-02-23

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20141021

FZDE Discontinued

Effective date: 20191113