CA2736877A1 - Clean genome bactofection - Google Patents
Clean genome bactofection Download PDFInfo
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- CA2736877A1 CA2736877A1 CA2736877A CA2736877A CA2736877A1 CA 2736877 A1 CA2736877 A1 CA 2736877A1 CA 2736877 A CA2736877 A CA 2736877A CA 2736877 A CA2736877 A CA 2736877A CA 2736877 A1 CA2736877 A1 CA 2736877A1
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| PCT/US2009/056829 WO2010030986A2 (en) | 2008-09-12 | 2009-09-14 | Clean genome bactofection |
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| CA2736877A1 true CA2736877A1 (en) | 2010-03-18 |
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| EP (1) | EP2344646A2 (enExample) |
| JP (1) | JP2012501680A (enExample) |
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| NZ593926A (en) * | 2009-01-23 | 2013-03-28 | Jackson H M Found Military Med | Methods and compositions based on shiga toxin type 2 protein |
| WO2013025248A1 (en) * | 2011-08-12 | 2013-02-21 | Mello Biotechnology, Inc. | Inducable expression from the eukaryotic pol -2 promoter in prokaryotes |
| EP2758530A4 (en) * | 2011-09-22 | 2015-04-29 | Jackson H M Found Military Med | SHIGELLA-DERIVED VECTOR AND USE METHOD THEREFOR |
| US11680273B2 (en) | 2011-09-23 | 2023-06-20 | Loma Linda University | Treatment of autoimmune diseases |
| DK2758074T3 (da) | 2011-09-23 | 2020-07-27 | Univ Loma Linda | Bakteriestammer der udtrykker methylasegener og anvendelser deraf |
| US10196662B2 (en) * | 2012-08-10 | 2019-02-05 | Mello Biotechnology, Inc. | Composition for producing microRNA precursors as drugs for enhancing wound healing and production method of the microRNA precursors |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| WO2019205057A1 (zh) * | 2018-04-26 | 2019-10-31 | 广州中科蓝华生物科技有限公司 | 一种启动子及其应用 |
| CN109402155A (zh) * | 2018-11-12 | 2019-03-01 | 川北医学院 | 一种双控延迟裂解性质粒及其构建方法与应用 |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| PH12022550724A1 (en) * | 2019-09-25 | 2024-05-13 | Univ Leuven Kath | Large vectors and methods for high-yield production |
| MY209860A (en) | 2020-02-13 | 2025-08-07 | Tenaya Therapeutics Inc | Gene therapy vectors for treating heart disease |
| US20240261394A1 (en) * | 2020-05-11 | 2024-08-08 | University Of Virginia Patent Foundation | Compositions and methods for inducing immune responses against class i fusion protein viruses |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| EP4346897A4 (en) * | 2021-06-02 | 2025-07-23 | Sivec Biotechnologies Llc | BACTERIAL DELIVERY OF ANTIBODIES, ANTIBODY DERIVATIVES AND POLYPEPTIDES TO EUKARYOTIC CELLS |
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| US6989265B2 (en) * | 2002-01-23 | 2006-01-24 | Wisconsin Alumni Research Foundation | Bacteria with reduced genome |
| US8178339B2 (en) * | 2005-08-20 | 2012-05-15 | Scarab Genomics Llc | Reduced genome E. coli |
| KR101420740B1 (ko) * | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
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- 2009-09-14 EP EP09792511A patent/EP2344646A2/en not_active Withdrawn
- 2009-09-14 JP JP2011527024A patent/JP2012501680A/ja active Pending
- 2009-09-14 WO PCT/US2009/056829 patent/WO2010030986A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010030986A3 (en) | 2010-06-24 |
| JP2012501680A (ja) | 2012-01-26 |
| EP2344646A2 (en) | 2011-07-20 |
| WO2010030986A2 (en) | 2010-03-18 |
| US20110165680A1 (en) | 2011-07-07 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20150915 |