CA2736626C - Genes associated with posttraumatic-stress disorder (ptsd) - Google Patents

Genes associated with posttraumatic-stress disorder (ptsd) Download PDF

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Publication number
CA2736626C
CA2736626C CA2736626A CA2736626A CA2736626C CA 2736626 C CA2736626 C CA 2736626C CA 2736626 A CA2736626 A CA 2736626A CA 2736626 A CA2736626 A CA 2736626A CA 2736626 C CA2736626 C CA 2736626C
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CA
Canada
Prior art keywords
gene
seq
coding sequence
expression level
ptsd
Prior art date
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Application number
CA2736626A
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English (en)
French (fr)
Other versions
CA2736626A1 (en
Inventor
Florian Holsboer
Marcus Ising
Rachel Yehuda
Joseph D. Buxbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Icahn School of Medicine at Mount Sinai
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Mount Sinai School of Medicine
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Publication of CA2736626A1 publication Critical patent/CA2736626A1/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2736626A 2008-09-12 2009-09-14 Genes associated with posttraumatic-stress disorder (ptsd) Active CA2736626C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08016126.8 2008-09-12
EP08016126 2008-09-12
PCT/EP2009/061890 WO2010029176A1 (en) 2008-09-12 2009-09-14 Genes associated with posttraumatic-stress disorder (ptsd)

Publications (2)

Publication Number Publication Date
CA2736626A1 CA2736626A1 (en) 2010-03-18
CA2736626C true CA2736626C (en) 2022-12-06

Family

ID=40084178

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2736626A Active CA2736626C (en) 2008-09-12 2009-09-14 Genes associated with posttraumatic-stress disorder (ptsd)

Country Status (4)

Country Link
US (1) US9243293B2 (de)
EP (1) EP2334816B1 (de)
CA (1) CA2736626C (de)
WO (1) WO2010029176A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9856532B2 (en) 2012-09-07 2018-01-02 Institute For Systems Biology Markers and methods for detecting posttraumatic stress disorder (PTSD)
CA2984623C (en) * 2015-05-18 2023-05-02 Corcept Therapeutics, Inc. Methods for diagnosing and assessing treatment for cushing's syndrome
JP2020504626A (ja) * 2016-12-09 2020-02-13 ロマ・リンダ・ユニバーシティ・ヘルス アルツハイマー病およびアルツハイマー病への進行のリスクを診断する方法
MX2019013257A (es) 2017-05-08 2020-01-13 Unilever Nv Prevencion y/o tratamiento de una enfermedad inflamatoria de la piel.
US11160982B2 (en) * 2017-07-05 2021-11-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating post-traumatic stress disorder in patients via renal neuromodulation
JP2021516956A (ja) * 2018-03-07 2021-07-15 アイカーン スクール オブ メディスン アット マウント サイナイＩｃａｈｎ Ｓｃｈｏｏｌ ｏｆ Ｍｅｄｉｃｉｎｅ ａｔ Ｍｔ． Ｓｉｎａｉ スフィンゴ脂質代謝タンパク質をコードするｍｏｄｒｎａ
US20210255198A1 (en) * 2018-06-11 2021-08-19 The United States of America as Represented by the Department of Veterans Affairs Office Methods for objective assessment of stress, early detection of risk for stress disorders, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs
EP3813871A4 (de) 2018-06-29 2022-10-12 Icahn School of Medicine at Mount Sinai Für anc80 codierende sphingolipid-metabolisierende proteine
KR102184840B1 (ko) * 2019-05-20 2020-11-30 이화여자대학교 산학협력단 외상 후 스트레스 장애 진단 또는 예측용 바이오마커 및 그의 용도
CN112143792A (zh) * 2020-09-30 2020-12-29 中国医学科学院病原生物学研究所 Rnf181作为结核病诊断分子标识的用途
WO2023077133A2 (en) * 2021-10-29 2023-05-04 The Johns Hopkins University Controlling homeostatic regulatory circuitry in hypothalamus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US6080560A (en) 1994-07-25 2000-06-27 Monsanto Company Method for producing antibodies in plant cells
WO2005017203A2 (en) * 2003-07-11 2005-02-24 Yale University Systems and methods for diagnosing and treating psychological and behavioral conditions
US20050176057A1 (en) 2003-09-26 2005-08-11 Troy Bremer Diagnostic markers of mood disorders and methods of use thereof
WO2006013561A2 (en) 2004-08-02 2006-02-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions and methods for diagnosing and treating post traumatic stress disorder

Also Published As

Publication number Publication date
US20120039812A1 (en) 2012-02-16
WO2010029176A1 (en) 2010-03-18
EP2334816A1 (de) 2011-06-22
US9243293B2 (en) 2016-01-26
CA2736626A1 (en) 2010-03-18
EP2334816B1 (de) 2013-11-20

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