CA2731398A1 - Improved organ protection, preservation and recovery - Google Patents
Improved organ protection, preservation and recovery Download PDFInfo
- Publication number
- CA2731398A1 CA2731398A1 CA2731398A CA2731398A CA2731398A1 CA 2731398 A1 CA2731398 A1 CA 2731398A1 CA 2731398 A CA2731398 A CA 2731398A CA 2731398 A CA2731398 A CA 2731398A CA 2731398 A1 CA2731398 A1 CA 2731398A1
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- tissue
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- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007903999 | 2007-07-25 | ||
| AU2007903999A AU2007903999A0 (en) | 2007-07-25 | Improved organ protection preservation and recovery | |
| PCT/AU2008/001086 WO2009012534A1 (en) | 2007-07-25 | 2008-07-25 | Improved organ protection, preservation and recovery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2731398A1 true CA2731398A1 (en) | 2009-01-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2731398A Abandoned CA2731398A1 (en) | 2007-07-25 | 2008-07-25 | Improved organ protection, preservation and recovery |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20100256083A1 (https=) |
| EP (1) | EP2219442A4 (https=) |
| JP (2) | JP2010534208A (https=) |
| KR (1) | KR20100081970A (https=) |
| CN (2) | CN103493799A (https=) |
| AU (1) | AU2008280836A1 (https=) |
| CA (1) | CA2731398A1 (https=) |
| SG (1) | SG185322A1 (https=) |
| WO (1) | WO2009012534A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ514515A (en) | 1999-03-23 | 2003-11-28 | Global Cardiac Solutions Pty L | Organ arrest, protection and preservation using a potassium channel operator and/or adenosine receptor and a local anaesthetic |
| AU2006345361B2 (en) | 2006-05-29 | 2014-04-10 | Hibernation Therapeutics, A Kf Llc | Improved tissue maintenance |
| CA2692256C (en) | 2006-07-25 | 2017-01-10 | Hibernation Therapeutics Limited | Trauma therapy |
| EP2173353B1 (en) | 2007-03-02 | 2015-05-06 | Hibernation Therapeutics, a KF LLC | Composition including Adenosine and Lignocaine |
| US8618056B2 (en) | 2007-12-22 | 2013-12-31 | Cuthbert O. Simpkins | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
| US8906855B2 (en) | 2007-12-22 | 2014-12-09 | Vivacelle Bio, Inc. | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries |
| CN102300555B (zh) * | 2009-01-30 | 2015-06-17 | 卡斯伯特·O·辛普金斯 | 复苏液 |
| GB201117095D0 (en) * | 2011-09-30 | 2011-11-16 | Univ Exeter The | Novel hydrogen sulfide releasing compounds |
| RU2502508C1 (ru) * | 2012-10-25 | 2013-12-27 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт кардиологии" Сибирского отделения Российской академии медицинских наук | Средство, имитирующее феномен посткондиционирования сердца |
| BR112016000809A2 (pt) | 2013-07-17 | 2017-08-22 | Hibernation Therapeuitics A Kf Llc | Método para tratar infecção, sepsia e lesão |
| WO2015185918A1 (en) | 2014-06-02 | 2015-12-10 | University Of Exeter | Combinations of a photosensitizer with a hydrogen sulfide donor, thioredoxin inhibitor or nitroxide for use in photodynamic therapy |
| WO2017164752A1 (en) * | 2016-03-22 | 2017-09-28 | Kameczura Tomasz | Cooling liquid, method, device and pericardial catheter for the heart hypothermia and application of the cooling liquid |
| US20230028322A1 (en) * | 2019-12-31 | 2023-01-26 | Miraki Innovation Think Tank Llc | Cold solution for inducing therapeutic hypothermia |
| AU2021206706A1 (en) * | 2020-01-10 | 2022-08-25 | President And Fellows Of Harvard College | Methods for inducing biostasis in a cell, tissue or organ |
| CN119867055B (zh) * | 2024-12-16 | 2025-12-26 | 中国农业科学院北京畜牧兽医研究所 | 蛋白质去乙酰化酶抑制剂3-typ在家禽精液超低温冷冻保存中的应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4798824A (en) * | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US5006512A (en) * | 1987-10-02 | 1991-04-09 | Tsuyoshi Ohnishi | Therapeutic usages of inhibitors for a potassium efflux channel |
| US5256770A (en) * | 1990-04-09 | 1993-10-26 | Schering Ag | Oxidation resistant thrombomodulin analogs |
| US5145771A (en) * | 1990-04-12 | 1992-09-08 | The University Of North Carolina At Chapel Hill | Rinse solution for organs and tissues |
| US5206222A (en) * | 1991-05-22 | 1993-04-27 | Vanderbilt University | Methods for the reduction of myocardial reperfusion injury |
| US5407793A (en) * | 1991-10-18 | 1995-04-18 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | An aqueous heart preservation and cardioplegia solution |
| RU2025973C1 (ru) * | 1992-02-10 | 1995-01-09 | Научно-производственное предприятие "Биофарм" | Раствор для консервации живых органов |
| US5370989A (en) * | 1992-04-03 | 1994-12-06 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| US5679706A (en) * | 1994-09-30 | 1997-10-21 | Bristol-Myers Squibb Company | Combination of a potassium channel activator and an antiarrhythmic agent |
| US5554497A (en) * | 1994-12-12 | 1996-09-10 | Charlotte-Mecklenburg Hospital Authority | Cardioplegic solution for arresting an organ |
| US5656420A (en) * | 1995-02-24 | 1997-08-12 | University Of Kentucky Research Foundation | Method for employing the delta opioid dadle to extend tissue survival time during ischemia |
| US6011017A (en) * | 1998-04-15 | 2000-01-04 | Cypros Pharmaceutical Corp. | Method of reducing pulmonary hypertension and atrial fibrillation after surgery using cardiopulmonary bypass |
| KR100269540B1 (ko) * | 1998-08-28 | 2000-10-16 | 윤종용 | 웨이퍼 상태에서의 칩 스케일 패키지 제조 방법 |
| US6358208B1 (en) * | 1998-11-21 | 2002-03-19 | Philipp Lang | Assessment of cardiovascular performance using ultrasound methods and devices that interrogate interstitial fluid |
| NZ514515A (en) * | 1999-03-23 | 2003-11-28 | Global Cardiac Solutions Pty L | Organ arrest, protection and preservation using a potassium channel operator and/or adenosine receptor and a local anaesthetic |
| AUPS312602A0 (en) * | 2002-06-21 | 2002-07-18 | James Cook University | Organ arrest, protection, preservation and recovery |
| US20040229780A1 (en) * | 2002-09-20 | 2004-11-18 | Olivera Baldomero M. | KappaM-conopeptides as organ protectants |
| GB2436255B (en) * | 2002-12-23 | 2007-11-28 | Global Cardiac Solutions Pty L | Organ preconditioning, arrest, protection, preservation and recovery |
| CA2551169A1 (en) * | 2002-12-23 | 2004-07-08 | Global Cardiac Solutions Pty Ltd | Organ preconditioning, arrest, protection, preservation and recovery |
| US6992075B2 (en) * | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
| EP1628649A4 (en) * | 2003-06-02 | 2010-06-02 | Samaritan Pharmaceuticals Inc | NEUROPROTECTIVE BENZOATE AND BENZAMIDE COMPOUNDS |
| US7049309B2 (en) * | 2003-10-14 | 2006-05-23 | Bristol-Myers Squibb Company | 3-Thia-4-arylquinolin-2-one potassium channel modulators |
| US20050076763A1 (en) * | 2003-10-14 | 2005-04-14 | Langeman Henry E. | Guitar baffle system |
| JP2008525468A (ja) * | 2004-12-22 | 2008-07-17 | エモリー・ユニバーシティ | ポストコンディショニング臓器保護作用を増強する治療補助薬 |
| AU2006345361B2 (en) * | 2006-05-29 | 2014-04-10 | Hibernation Therapeutics, A Kf Llc | Improved tissue maintenance |
| CA2692256C (en) * | 2006-07-25 | 2017-01-10 | Hibernation Therapeutics Limited | Trauma therapy |
-
2008
- 2008-07-25 SG SG2012077921A patent/SG185322A1/en unknown
- 2008-07-25 CN CN201310339723.XA patent/CN103493799A/zh active Pending
- 2008-07-25 EP EP08772710A patent/EP2219442A4/en not_active Ceased
- 2008-07-25 JP JP2010517236A patent/JP2010534208A/ja not_active Withdrawn
- 2008-07-25 KR KR1020107004212A patent/KR20100081970A/ko not_active Ceased
- 2008-07-25 US US12/670,452 patent/US20100256083A1/en not_active Abandoned
- 2008-07-25 WO PCT/AU2008/001086 patent/WO2009012534A1/en not_active Ceased
- 2008-07-25 CA CA2731398A patent/CA2731398A1/en not_active Abandoned
- 2008-07-25 AU AU2008280836A patent/AU2008280836A1/en not_active Abandoned
- 2008-07-25 CN CN200880108561A patent/CN101808509A/zh active Pending
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2013
- 2013-07-17 US US13/944,246 patent/US20130302779A1/en not_active Abandoned
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2014
- 2014-07-14 JP JP2014143955A patent/JP2014196351A/ja active Pending
- 2014-10-03 US US14/506,271 patent/US20150038447A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SG185322A1 (en) | 2012-11-29 |
| EP2219442A4 (en) | 2012-05-02 |
| US20130302779A1 (en) | 2013-11-14 |
| US20150038447A1 (en) | 2015-02-05 |
| US20100256083A1 (en) | 2010-10-07 |
| WO2009012534A1 (en) | 2009-01-29 |
| EP2219442A1 (en) | 2010-08-25 |
| KR20100081970A (ko) | 2010-07-15 |
| CN103493799A (zh) | 2014-01-08 |
| JP2010534208A (ja) | 2010-11-04 |
| CN101808509A (zh) | 2010-08-18 |
| AU2008280836A1 (en) | 2009-01-29 |
| JP2014196351A (ja) | 2014-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130710 |
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| FZDE | Discontinued |
Effective date: 20150727 |