CA2730933A1 - Recombinant pokeweed antiviral proteins, compositions and methods related thereto - Google Patents
Recombinant pokeweed antiviral proteins, compositions and methods related thereto Download PDFInfo
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- CA2730933A1 CA2730933A1 CA 2730933 CA2730933A CA2730933A1 CA 2730933 A1 CA2730933 A1 CA 2730933A1 CA 2730933 CA2730933 CA 2730933 CA 2730933 A CA2730933 A CA 2730933A CA 2730933 A1 CA2730933 A1 CA 2730933A1
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- rpap
- lys6
- gmbs
- conjugate
- full length
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- 238000000746 purification Methods 0.000 description 1
- 230000001698 pyrogenic effect Effects 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000010837 receptor-mediated endocytosis Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000003161 ribonuclease inhibitor Substances 0.000 description 1
- 238000013341 scale-up Methods 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 238000001542 size-exclusion chromatography Methods 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229960002317 succinimide Drugs 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000007888 toxin activity Effects 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8077308P | 2008-07-15 | 2008-07-15 | |
| US61/080,773 | 2008-07-15 | ||
| PCT/US2009/050685 WO2010009227A2 (en) | 2008-07-15 | 2009-07-15 | Recombinant pokeweed antiviral proteins, compositions and methods related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2730933A1 true CA2730933A1 (en) | 2010-01-21 |
Family
ID=41319605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2730933 Abandoned CA2730933A1 (en) | 2008-07-15 | 2009-07-15 | Recombinant pokeweed antiviral proteins, compositions and methods related thereto |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8575109B2 (OSRAM) |
| EP (1) | EP2318431B1 (OSRAM) |
| JP (1) | JP2011528230A (OSRAM) |
| AU (1) | AU2009270920A1 (OSRAM) |
| CA (1) | CA2730933A1 (OSRAM) |
| WO (1) | WO2010009227A2 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010009227A2 (en) | 2008-07-15 | 2010-01-21 | Cedus, Inc. | Recombinant pokeweed antiviral proteins, compositions and methods related thereto |
| CN102286097B (zh) * | 2011-06-20 | 2013-04-24 | 中国农业科学院植物保护研究所 | 人工合成的美洲商陆抗病毒蛋白（pap）抗原、抗体及其制备方法、应用 |
| EP3440211A4 (en) * | 2016-04-04 | 2019-09-04 | Ophiuchus Medicine Inc. | MEDICAL PLANTS |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5186090A (en) | 1989-02-23 | 1990-09-26 | Colorado State University Research Foundation | Gnrh analogs for destroying gonadotrophs |
| US20050277582A1 (en) * | 1993-07-20 | 2005-12-15 | Nett Torrance M | Method for inactivating gonadotrophs |
| AU2005281743A1 (en) * | 2004-08-04 | 2006-03-16 | Cytos Biotechnology Ag | Carrier conjugates of GnRH-peptides |
| US20070141548A1 (en) * | 2005-03-11 | 2007-06-21 | Jorg Kohl | Organ transplant solutions and method for transplanting organs |
| WO2010009227A2 (en) | 2008-07-15 | 2010-01-21 | Cedus, Inc. | Recombinant pokeweed antiviral proteins, compositions and methods related thereto |
-
2009
- 2009-07-15 WO PCT/US2009/050685 patent/WO2010009227A2/en not_active Ceased
- 2009-07-15 AU AU2009270920A patent/AU2009270920A1/en not_active Abandoned
- 2009-07-15 JP JP2011518880A patent/JP2011528230A/ja active Pending
- 2009-07-15 EP EP20090790464 patent/EP2318431B1/en not_active Not-in-force
- 2009-07-15 US US13/054,187 patent/US8575109B2/en not_active Expired - Fee Related
- 2009-07-15 CA CA 2730933 patent/CA2730933A1/en not_active Abandoned
-
2013
- 2013-10-03 US US14/045,437 patent/US9023596B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010009227A3 (en) | 2010-04-29 |
| AU2009270920A1 (en) | 2010-01-21 |
| WO2010009227A2 (en) | 2010-01-21 |
| US20140094592A1 (en) | 2014-04-03 |
| JP2011528230A (ja) | 2011-11-17 |
| US9023596B2 (en) | 2015-05-05 |
| EP2318431B1 (en) | 2015-03-18 |
| EP2318431A2 (en) | 2011-05-11 |
| US20110281299A1 (en) | 2011-11-17 |
| US8575109B2 (en) | 2013-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140708 |
|
| FZDE | Dead |
Effective date: 20180227 |