CA2720326C - Cartridge device for processing a sample mounted on a surface of a support member - Google Patents
Cartridge device for processing a sample mounted on a surface of a support member Download PDFInfo
- Publication number
- CA2720326C CA2720326C CA2720326A CA2720326A CA2720326C CA 2720326 C CA2720326 C CA 2720326C CA 2720326 A CA2720326 A CA 2720326A CA 2720326 A CA2720326 A CA 2720326A CA 2720326 C CA2720326 C CA 2720326C
- Authority
- CA
- Canada
- Prior art keywords
- support member
- cavity
- compartment
- sample
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000012545 processing Methods 0.000 title claims abstract description 84
- 239000011159 matrix material Substances 0.000 claims abstract description 7
- 239000012530 fluid Substances 0.000 claims description 60
- 239000000463 material Substances 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 5
- 229920001821 foam rubber Polymers 0.000 claims description 3
- 239000004033 plastic Substances 0.000 claims description 3
- 229920003023 plastic Polymers 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000004417 polycarbonate Substances 0.000 claims description 2
- 229920000515 polycarbonate Polymers 0.000 claims description 2
- 239000004793 Polystyrene Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims 1
- 229920006393 polyether sulfone Polymers 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 239000000523 sample Substances 0.000 description 116
- 239000007788 liquid Substances 0.000 description 63
- 239000003153 chemical reaction reagent Substances 0.000 description 24
- 238000000034 method Methods 0.000 description 22
- 210000004027 cell Anatomy 0.000 description 12
- 239000000758 substrate Substances 0.000 description 12
- 230000009471 action Effects 0.000 description 8
- 239000012620 biological material Substances 0.000 description 8
- 239000003570 air Substances 0.000 description 6
- 238000001704 evaporation Methods 0.000 description 6
- 230000008020 evaporation Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 239000002775 capsule Substances 0.000 description 4
- 238000004891 communication Methods 0.000 description 4
- 238000004043 dyeing Methods 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 239000003446 ligand Substances 0.000 description 4
- 239000006187 pill Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000003892 spreading Methods 0.000 description 4
- 230000007480 spreading Effects 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 102000053602 DNA Human genes 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 229920002477 rna polymer Polymers 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 241000233866 Fungi Species 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
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- 238000001514 detection method Methods 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 239000001828 Gelatine Substances 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 235000013681 dietary sucrose Nutrition 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- OYFJQPXVCSSHAI-QFPUQLAESA-N enalapril maleate Chemical compound OC(=O)\C=C/C(O)=O.C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 OYFJQPXVCSSHAI-QFPUQLAESA-N 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 239000013056 hazardous product Substances 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK1516/97 | 1997-12-23 | ||
| DK151697 | 1997-12-23 | ||
| CA2315809A CA2315809C (en) | 1997-12-23 | 1998-12-23 | Cartridge device for processing a sample mounted on a surface of a support member |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2315809A Division CA2315809C (en) | 1997-12-23 | 1998-12-23 | Cartridge device for processing a sample mounted on a surface of a support member |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2720326A1 CA2720326A1 (en) | 1999-07-08 |
| CA2720326C true CA2720326C (en) | 2014-11-25 |
Family
ID=8105656
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2720326A Expired - Lifetime CA2720326C (en) | 1997-12-23 | 1998-12-23 | Cartridge device for processing a sample mounted on a surface of a support member |
| CA2315809A Expired - Lifetime CA2315809C (en) | 1997-12-23 | 1998-12-23 | Cartridge device for processing a sample mounted on a surface of a support member |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2315809A Expired - Lifetime CA2315809C (en) | 1997-12-23 | 1998-12-23 | Cartridge device for processing a sample mounted on a surface of a support member |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030138353A1 (enExample) |
| EP (1) | EP1042662B1 (enExample) |
| JP (1) | JP2002500353A (enExample) |
| AT (1) | ATE347098T1 (enExample) |
| AU (1) | AU1752499A (enExample) |
| CA (2) | CA2720326C (enExample) |
| DE (1) | DE69836562T2 (enExample) |
| WO (1) | WO1999034190A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6673620B1 (en) | 1999-04-20 | 2004-01-06 | Cytologix Corporation | Fluid exchange in a chamber on a microscope slide |
| DE60040977D1 (de) | 1999-04-20 | 2009-01-15 | Cytologix Corp | Flüssigkeitswechsel in einer kammer auf einem mikroskopobjektträger |
| AU6079500A (en) | 1999-07-08 | 2001-01-30 | Lee Angros | Antigen recovery and/or staining apparatus and method |
| DE19932958C2 (de) * | 1999-07-14 | 2003-08-07 | Walter Schubert | Vorrichtung zur Bindung von Molekülen, Molekülgruppen, Molekülteilen und/oder Zellen |
| AU5967900A (en) | 1999-07-21 | 2001-02-13 | Dako A/S | A method of controlling the temperature of a specimen in or on a solid support member |
| FR2806166B1 (fr) * | 2000-03-09 | 2002-11-15 | Genomic Sa | Automate pour traitement, acquisition de signal et analyse de biopuces |
| US6773677B2 (en) * | 2002-01-09 | 2004-08-10 | Caliper Life Sciences, Inc. | Slide cassette for fluidic injection |
| US11249095B2 (en) * | 2002-04-15 | 2022-02-15 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| US7468161B2 (en) | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| US6620623B1 (en) * | 2002-05-06 | 2003-09-16 | The University Of Chicago | Biochip reader with enhanced illumination and bioarray positioning apparatus |
| US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| WO2004069409A2 (en) * | 2003-01-31 | 2004-08-19 | Discovery Partners International | Automated sample analysis system and method |
| DK1843850T3 (en) | 2005-01-31 | 2015-12-07 | Realbio Technologies Ltd | LATERAL FLOW STEERING CAPILLAR DEVICE |
| EP1724564A1 (en) * | 2005-05-18 | 2006-11-22 | Miltenyi Biotec GmbH | Improved sample chamber for an analyzing device. |
| AU2006249956A1 (en) | 2005-05-24 | 2006-11-30 | Angros, Lee H | In situ heat induced antigen recovery and staining apparatus and method |
| EP1829613B1 (de) * | 2006-03-02 | 2022-03-30 | Nexus Biosystems, Inc. | Aufbewahrungseinheit und Transfersystem zum Aufbewahren und Bereitstellen von Biologischen proben |
| JP5061240B2 (ja) * | 2007-07-10 | 2012-10-31 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 生物学的サンプル処理用装置と方法 |
| EP2028882B1 (en) * | 2007-08-01 | 2018-10-10 | Yamaha Corporation | Remote audio monitoring system for amplifiers in a network |
| EP2326419B1 (en) | 2008-06-29 | 2021-04-07 | Realbio Technologies Ltd. | Liquid transfer device particularly useful as a capturing device in a biological assay process |
| WO2010025425A1 (en) | 2008-08-29 | 2010-03-04 | Angros Lee H | Multiplexed microscope slide staining apparatus |
| FR2936251B1 (fr) * | 2008-09-23 | 2010-11-05 | Millipore Corp | Dispositif pour l'analyse microbiologique. |
| FR2936252B1 (fr) | 2008-09-23 | 2010-11-05 | Millipore Corp | Dispositif pour l'analyse microbiologique. |
| DE102009015596A1 (de) | 2009-03-30 | 2010-10-21 | Dcs Innovative Diagnostik-Systeme Dr. Christian Sartori Gmbh & Co. Kg | Verfahren und Vorrichtung zur Behandlung von trägerfixiertem Material |
| US10746752B2 (en) | 2009-11-13 | 2020-08-18 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
| US9498791B2 (en) | 2009-11-13 | 2016-11-22 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
| EP2499500B1 (en) | 2009-11-13 | 2020-12-30 | Ventana Medical Systems, Inc. | Thin film processing apparatuses for adjustable volume accommodation |
| JP2011155921A (ja) * | 2010-02-02 | 2011-08-18 | Seiko Epson Corp | バイオチップ、検体反応装置及び検体反応方法 |
| WO2013095729A1 (en) * | 2011-12-22 | 2013-06-27 | Life Technologies Corporation | Sequential lateral flow capillary device for analyte determination |
| CA2890819C (en) * | 2012-12-26 | 2017-05-16 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for moderating evaporation |
| HU230739B1 (hu) * | 2013-02-28 | 2018-01-29 | 3Dhistech Kft. | Berendezés és eljárás tárgylemezek automatikus festésére, fedésére, digitalizálására integrált tárgylemez festő-fedő-digitalizáló automata berendezés segítségével |
| USD728120S1 (en) | 2013-03-15 | 2015-04-28 | Ventana Medical Systems, Inc. | Arcuate member for moving liquids along a microscope slide |
| US10634590B2 (en) * | 2014-03-11 | 2020-04-28 | Emd Millipore Corporation | IHC, tissue slide fluid exchange disposable and system |
| JP6085268B2 (ja) * | 2014-05-04 | 2017-02-22 | 日理工業株式会社 | イオン濃縮装置 |
| CN107615039A (zh) * | 2015-05-26 | 2018-01-19 | 奥林巴斯株式会社 | 检查体染色装置和检查体染色方法 |
| EP3239665A1 (de) * | 2016-04-25 | 2017-11-01 | Weickmann & Weickmann PartmbB | Sensorgehäuse |
| JP6908624B2 (ja) | 2016-04-27 | 2021-07-28 | ベンタナ メディカル システムズ， インコーポレイテッド | リアルタイム体積制御するためのシステムおよび方法 |
| EP3523622B1 (en) * | 2016-10-06 | 2025-04-30 | Ventana Medical Systems, Inc. | System, method and kit for sample preparation |
| EP3385771B1 (de) * | 2017-04-05 | 2023-10-25 | Leica Mikrosysteme GmbH | Haltevorrichtung für probenträger und verfahren zum ein- und ausbringen eines probenträgers |
| US11986831B2 (en) | 2017-08-17 | 2024-05-21 | Leica Biosystems Melbourne Pty Ltd | Sample processing assembly |
| EP3894585A2 (en) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| EP4263060A4 (en) * | 2020-12-21 | 2024-07-03 | Conservation X Labs, Inc. | Systems and methods using hand-held devices for detecting a target analyte loaded on a cartridge |
| ES2989523T3 (es) | 2021-02-19 | 2024-11-26 | 10X Genomics Inc | Método de uso de un dispositivo modular de soporte para ensayos |
| US12553805B2 (en) | 2021-08-02 | 2026-02-17 | 10X Genomics, Inc. | Methods of preserving a biological sample |
| USD1038429S1 (en) * | 2021-10-15 | 2024-08-06 | Standard BioTools Inc. | Scientific instrument |
| CN114088756A (zh) * | 2021-12-20 | 2022-02-25 | 北京中科科仪股份有限公司 | 样品接入装置及扫描电镜 |
| USD1046189S1 (en) * | 2021-12-23 | 2024-10-08 | Tecan Genomics, Inc. | Laboratory apparatus |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8722902D0 (en) * | 1987-09-30 | 1987-11-04 | Shandon Southern Prod | Tissue &c processing |
| EP0682775B1 (en) * | 1993-02-03 | 1998-05-06 | HISTAGGEN Incorporated | Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials |
| EP0729021A1 (de) * | 1995-02-25 | 1996-08-28 | Roche Diagnostics GmbH | Vorrichtung zur Bearbeitung von Proben auf Objektträgern |
-
1998
- 1998-12-23 AU AU17524/99A patent/AU1752499A/en not_active Abandoned
- 1998-12-23 WO PCT/DK1998/000580 patent/WO1999034190A1/en not_active Ceased
- 1998-12-23 CA CA2720326A patent/CA2720326C/en not_active Expired - Lifetime
- 1998-12-23 EP EP98962304A patent/EP1042662B1/en not_active Expired - Lifetime
- 1998-12-23 JP JP2000526792A patent/JP2002500353A/ja active Pending
- 1998-12-23 AT AT98962304T patent/ATE347098T1/de not_active IP Right Cessation
- 1998-12-23 CA CA2315809A patent/CA2315809C/en not_active Expired - Lifetime
- 1998-12-23 DE DE69836562T patent/DE69836562T2/de not_active Expired - Lifetime
-
1999
- 1999-02-24 US US09/256,116 patent/US20030138353A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU1752499A (en) | 1999-07-19 |
| CA2720326A1 (en) | 1999-07-08 |
| EP1042662A1 (en) | 2000-10-11 |
| DE69836562T2 (de) | 2007-10-04 |
| DE69836562D1 (de) | 2007-01-11 |
| EP1042662B1 (en) | 2006-11-29 |
| US20030138353A1 (en) | 2003-07-24 |
| CA2315809C (en) | 2014-06-03 |
| ATE347098T1 (de) | 2006-12-15 |
| JP2002500353A (ja) | 2002-01-08 |
| CA2315809A1 (en) | 1999-07-08 |
| WO1999034190A1 (en) | 1999-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20181224 |