CA2707442A1 - Derives de tetrahydro-beta-carboline antibiotiques - Google Patents

Derives de tetrahydro-beta-carboline antibiotiques Download PDF

Info

Publication number
CA2707442A1
CA2707442A1 CA2707442A CA2707442A CA2707442A1 CA 2707442 A1 CA2707442 A1 CA 2707442A1 CA 2707442 A CA2707442 A CA 2707442A CA 2707442 A CA2707442 A CA 2707442A CA 2707442 A1 CA2707442 A1 CA 2707442A1
Authority
CA
Canada
Prior art keywords
aryl
alkyl
compound
independently
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2707442A
Other languages
English (en)
Inventor
Roger Frechette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Roger Frechette
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scientific Management Pty Ltd, Roger Frechette filed Critical Biota Scientific Management Pty Ltd
Publication of CA2707442A1 publication Critical patent/CA2707442A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA2707442A 2007-11-30 2008-11-26 Derives de tetrahydro-beta-carboline antibiotiques Abandoned CA2707442A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99152007P 2007-11-30 2007-11-30
US60/991,520 2007-11-30
PCT/US2008/084832 WO2009102377A2 (fr) 2007-11-30 2008-11-26 Dérivés de tétrahydro-bêta-carboline antibiotiques

Publications (1)

Publication Number Publication Date
CA2707442A1 true CA2707442A1 (fr) 2009-08-20

Family

ID=40957421

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2707442A Abandoned CA2707442A1 (fr) 2007-11-30 2008-11-26 Derives de tetrahydro-beta-carboline antibiotiques

Country Status (6)

Country Link
EP (1) EP2240493A2 (fr)
JP (1) JP2011518108A (fr)
CN (1) CN102007130A (fr)
AU (1) AU2008350293A1 (fr)
CA (1) CA2707442A1 (fr)
WO (1) WO2009102377A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124616B2 (en) 2007-11-30 2012-02-28 Biota Scientific Management Pty Ltd Bicyclic PPAT inhibitors as antibacterial agents
WO2012127885A1 (fr) 2011-03-18 2012-09-27 小野薬品工業株式会社 Dérivé de tétrahydrocarboline
CN103070862A (zh) * 2011-10-25 2013-05-01 新疆华世丹药物研究有限责任公司 去氢骆驼蓬碱衍生物在制备抗菌药物中的应用
CN114478525B (zh) * 2022-03-28 2023-05-30 山东京博农化科技股份有限公司 一种四氢-β-咔啉吡唑酰胺衍生物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6987115B2 (en) * 2000-12-08 2006-01-17 Smithkline Beecham Corporation Antibacterial compounds
AU2004234405A1 (en) * 2003-04-29 2004-11-11 Arqule, Inc. Antibiotic tetrahydro-beta-carboline derivatives

Also Published As

Publication number Publication date
WO2009102377A3 (fr) 2009-11-05
EP2240493A2 (fr) 2010-10-20
CN102007130A (zh) 2011-04-06
WO2009102377A2 (fr) 2009-08-20
AU2008350293A1 (en) 2009-08-20
JP2011518108A (ja) 2011-06-23

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Legal Events

Date Code Title Description
FZDE Dead

Effective date: 20121126