CA2704539C - Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate - Google Patents

Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate Download PDF

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Publication number
CA2704539C
CA2704539C CA2704539A CA2704539A CA2704539C CA 2704539 C CA2704539 C CA 2704539C CA 2704539 A CA2704539 A CA 2704539A CA 2704539 A CA2704539 A CA 2704539A CA 2704539 C CA2704539 C CA 2704539C
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CA
Canada
Prior art keywords
xylose
acetate
hima
gene
strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2704539A
Other languages
English (en)
French (fr)
Other versions
CA2704539A1 (en
Inventor
Paul V. Viitanen
Luan Tao
Kyle Knoke
Yuying Zhang
Perry G. Caimi
Min Zhang
Yat-Chen Chou
Mary Ann Franden
Original Assignee
EI Du Pont de Nemours and Co
Alliance for Sustainable Energy LLC
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Application filed by EI Du Pont de Nemours and Co, Alliance for Sustainable Energy LLC filed Critical EI Du Pont de Nemours and Co
Publication of CA2704539A1 publication Critical patent/CA2704539A1/en
Application granted granted Critical
Publication of CA2704539C publication Critical patent/CA2704539C/en
Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA2704539A 2007-10-30 2008-10-30 Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate Expired - Fee Related CA2704539C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98376107P 2007-10-30 2007-10-30
US60/983,761 2007-10-30
PCT/US2008/081694 WO2009058938A2 (en) 2007-10-30 2008-10-30 Process for the production of ethanol from a medium comprising xylose, employing a recombinant zymomonas strain having a reduced hima expression

Publications (2)

Publication Number Publication Date
CA2704539A1 CA2704539A1 (en) 2009-05-07
CA2704539C true CA2704539C (en) 2014-12-23

Family

ID=40551263

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2704539A Expired - Fee Related CA2704539C (en) 2007-10-30 2008-10-30 Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate

Country Status (11)

Country Link
US (1) US7897396B2 (https=)
EP (1) EP2205753B1 (https=)
JP (1) JP2011515067A (https=)
CN (1) CN101883861B (https=)
AT (1) ATE506447T1 (https=)
AU (1) AU2008318720B2 (https=)
BR (1) BRPI0817152A8 (https=)
CA (1) CA2704539C (https=)
DE (1) DE602008006446D1 (https=)
ES (1) ES2361385T3 (https=)
WO (1) WO2009058938A2 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8247208B2 (en) * 2008-12-22 2012-08-21 Alliance For Sustainable Energy Llc Zymomonas with improved xylose utilization in stress conditions
US20110143408A1 (en) * 2009-06-18 2011-06-16 E. I. Du Pont De Nemours And Company Zymomonas with improved arabinose utilization
US8647850B2 (en) 2009-12-23 2014-02-11 E I Du Pont De Nemours And Company Process for simultaneous saccharification and fermentation for production of ethanol
US9040263B2 (en) 2010-07-28 2015-05-26 Butamax Advanced Biofuels Llc Production of alcohol esters and in situ product removal during alcohol fermentation
US9206448B2 (en) 2010-06-18 2015-12-08 Butamax Advanced Biofuels Llc Extraction solvents derived from oil for alcohol removal in extractive fermentation
JP2013533742A (ja) 2010-06-18 2013-08-29 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 抽出発酵におけるアルコール除去のための、油に由来する抽出溶媒
US8679822B2 (en) 2010-06-29 2014-03-25 E I Du Pont De Nemours And Company Xylose utilization in recombinant zymomonas
IL207945A0 (en) 2010-09-02 2010-12-30 Robert Jansen Method for the production of carbohydrates
US8476048B2 (en) 2010-12-17 2013-07-02 E I Du Pont De Nemours And Company Xylose utilizing zymomonas mobilis with improved ethanol production in biomass hydrolysate medium
US20130040340A1 (en) 2011-02-07 2013-02-14 E. I. Du Pont De Nemours And Company Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms
US8765425B2 (en) 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8765426B2 (en) 2011-04-07 2014-07-01 E I Du Pont De Nemours And Company Pantothenic acid biosynthesis in zymomonas
EP2721163B1 (en) 2011-06-17 2016-12-21 Butamax Advanced Biofuels LLC Co-products from biofuel production processes and methods of making
EP2788096A2 (en) 2011-12-09 2014-10-15 Butamax Advanced Biofuels LLC Process to remove product alcohols from fermentation broth
US20130157332A1 (en) 2011-12-20 2013-06-20 E I Du Pont De Nemours And Company Gene inactivation allowing immediate growth on xylose medium by engineered zymomonas
US9732362B2 (en) 2012-05-04 2017-08-15 Butamax Advanced Biofuels Llc Processes and systems for alcohol production and recovery
US8697426B2 (en) 2012-06-15 2014-04-15 E I Du Pont De Nemours And Company Contaminant control in Zymomonas fermentation using virginiamycin
US8759069B2 (en) 2012-06-15 2014-06-24 E I Du Pont De Nemours And Company Contaminant control in Zymomonas fermentation using hop acids
US20140024064A1 (en) 2012-07-23 2014-01-23 Butamax(Tm) Advanced Biofuels Llc Processes and systems for the production of fermentative alcohols
WO2014043288A1 (en) 2012-09-12 2014-03-20 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
WO2014047412A1 (en) 2012-09-21 2014-03-27 Butamax(Tm) Advanced Biofuels Llc A method for producing butanol using two-phase extractive fermentation and recyclable extractant compositions
CA2887574A1 (en) 2012-10-11 2014-04-17 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
WO2014081848A1 (en) 2012-11-20 2014-05-30 Butamax Advanced Biofuels Llc Butanol purification
US8846357B2 (en) 2012-12-20 2014-09-30 E I Du Pont De Nemours And Company Stabilized chlorine dioxide for contamination control in Zymomonas fermentation
US20160002131A1 (en) 2013-02-21 2016-01-07 Butamax Advanced Biofuels Llc Vapor recompression
WO2014159309A1 (en) 2013-03-12 2014-10-02 Butamax Advanced Biofuels Llc Processes and systems for the production of alcohols
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
AU2014244216A1 (en) 2013-03-14 2015-09-24 E.I. Du Pont De Nemours And Company Glycerol 3- phosphate dehydrogenase for butanol production
WO2014151645A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Process for maximizing biomass growth and butanol yield by feedback control
US9156760B2 (en) 2013-03-15 2015-10-13 Butamax Advanced Biofuels Llc Method for production of butanol using extractive fermentation
WO2014144643A1 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
US9206445B2 (en) 2013-04-29 2015-12-08 Alliance For Sustainable Energy, Llc Biocatalysts with enhanced inhibitor tolerance
US9663759B2 (en) 2013-07-03 2017-05-30 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
US20150087040A1 (en) 2013-09-26 2015-03-26 E I Du Pont De Nemours And Company Production of ethanol and recycle water in a cellulosic fermentation process
US20150087041A1 (en) 2013-09-26 2015-03-26 E I Du Pont De Nemours And Company Production of ethanol with reduced contaminants in a cellulosic biomass based process
US20150147786A1 (en) 2013-11-24 2015-05-28 E I Du Pont De Nemours And Company High force and high stress destructuring for starch biomass processing
WO2017116840A1 (en) 2015-12-28 2017-07-06 Danisco Us Inc. Methods for the production of fermentation products from feedstock

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5789210A (en) * 1993-11-08 1998-08-04 Purdue Research Foundation Recombinant yeasts for effective fermentation of glucose and xylose
US5514583A (en) 1994-04-15 1996-05-07 Midwest Research Institute Recombinant zymomonas for pentose fermentation
US5843760A (en) 1994-04-15 1998-12-01 Midwest Research Institute Single zymomonas mobilis strain for xylose and arabinose fermentation
US5712133A (en) 1994-04-15 1998-01-27 Midwest Research Institute Pentose fermentation by recombinant zymomonas
AU2388295A (en) 1994-04-15 1995-11-10 Midwest Research Institute Recombinant zymomonas for pentose fermentation
IN191596B (https=) * 1996-05-06 2003-12-06 Purdue Research Foundation
AU4992601A (en) * 2000-05-01 2001-11-12 Midwest Research Inst Stable zymomonas mobilis xylose and arabinose fermenting strains
US7223575B2 (en) * 2000-05-01 2007-05-29 Midwest Research Institute Zymomonas pentose-sugar fermenting strains and uses thereof
US6566107B1 (en) 2000-11-01 2003-05-20 Midwest Research Institute Recombinant Zymomonas mobilis with improved xylose utilization
US20040231060A1 (en) 2003-03-07 2004-11-25 Athenix Corporation Methods to enhance the activity of lignocellulose-degrading enzymes
EP1869194A2 (en) * 2005-04-12 2007-12-26 E.I.Du pont de nemours and company Treatment of biomass to obtain a target chemical
US7629156B2 (en) 2006-09-28 2009-12-08 E.I. Du Pont De Nemours And Company Ethanol production in fermentation of mixed sugars containing xylose
US7741084B2 (en) 2006-09-28 2010-06-22 E. I. Du Pont De Nemours And Company Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas

Also Published As

Publication number Publication date
EP2205753A2 (en) 2010-07-14
JP2011515067A (ja) 2011-05-19
EP2205753B1 (en) 2011-04-20
US20090203099A1 (en) 2009-08-13
CN101883861A (zh) 2010-11-10
ES2361385T3 (es) 2011-06-16
US7897396B2 (en) 2011-03-01
WO2009058938A2 (en) 2009-05-07
ATE506447T1 (de) 2011-05-15
CN101883861B (zh) 2013-12-11
CA2704539A1 (en) 2009-05-07
AU2008318720B2 (en) 2013-09-26
BRPI0817152A8 (pt) 2018-12-11
DE602008006446D1 (de) 2011-06-01
AU2008318720A1 (en) 2009-05-07
WO2009058938A3 (en) 2009-06-18
BRPI0817152A2 (pt) 2015-11-24

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