CA2701537A1 - Compositions pour le traitement de tumeurs par l'administration directe d'un radio-isotope - Google Patents
Compositions pour le traitement de tumeurs par l'administration directe d'un radio-isotope Download PDFInfo
- Publication number
- CA2701537A1 CA2701537A1 CA2701537A CA2701537A CA2701537A1 CA 2701537 A1 CA2701537 A1 CA 2701537A1 CA 2701537 A CA2701537 A CA 2701537A CA 2701537 A CA2701537 A CA 2701537A CA 2701537 A1 CA2701537 A1 CA 2701537A1
- Authority
- CA
- Canada
- Prior art keywords
- radioisotope
- composition
- bone
- administration
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/025—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus inorganic Tc complexes or compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
- A61K51/048—DTPA (diethylenetriamine tetraacetic acid)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99787307P | 2007-10-05 | 2007-10-05 | |
US99785607P | 2007-10-05 | 2007-10-05 | |
US60/997,873 | 2007-10-05 | ||
US60/997,856 | 2007-10-05 | ||
PCT/US2008/002026 WO2009045230A1 (fr) | 2007-10-05 | 2008-02-15 | Compositions pour le traitement de tumeurs par l'administration directe d'un radio-isotope |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2701537A1 true CA2701537A1 (fr) | 2009-04-09 |
Family
ID=40526495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2701537A Abandoned CA2701537A1 (fr) | 2007-10-05 | 2008-02-15 | Compositions pour le traitement de tumeurs par l'administration directe d'un radio-isotope |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2195036A4 (fr) |
JP (1) | JP2010540627A (fr) |
CA (1) | CA2701537A1 (fr) |
WO (1) | WO2009045230A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007008232A2 (fr) | 2004-09-03 | 2007-01-18 | Board Of Regents, The University Of Texas System | Ablation locoregionale interne de tissus anormaux par des radionucleides |
DOP2010000279A (es) * | 2009-09-18 | 2012-06-15 | Sari Asher Llc | Composiciones radiofarmaceuticas no-coloidales sin sellar y metodos para el tratamiento de tejido anormal |
JP5871823B2 (ja) * | 2010-03-09 | 2016-03-01 | クリオン インコーポレイテッド | 同位体特定分離及びイオン特定媒体を使用するガラス固化 |
GB2490317A (en) * | 2011-04-19 | 2012-10-31 | Dspi Ltd | Radioactive solution undergoing in situ precipitation at a tumour site for cancer therapy |
US9687574B2 (en) | 2011-12-21 | 2017-06-27 | Isotherapeutics Group Llc | Radioactive compositions and methods for their therapeutic use |
EP2831889B1 (fr) | 2012-03-26 | 2018-11-21 | Kurion, Inc. | Régénération sélective de résines de milieux spécifiques à un isotope dans des systèmes pour séparation d'isotopes radioactifs de matières de déchets liquides |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849209A (en) * | 1985-06-07 | 1989-07-18 | Cadema Medical Products, Inc. | Treatment of arthritis, including rheumatoid arthritis with 166 Holmium radionuclide |
US4915932A (en) * | 1987-10-14 | 1990-04-10 | Australian Nuclear Science & Technology Organisation | Macroaggregates for radiation synovectomy |
EP1389090A2 (fr) * | 2001-04-26 | 2004-02-18 | Board of Regents, The University of Texas System | Compositions d'imagerie diagnostique, leurs methodes de synthese et utilisation |
WO2004050168A2 (fr) * | 2002-11-27 | 2004-06-17 | Board Of Regents, The University Of Texas System | Produits radiopharmaceutiques et microspheres radioactives pour ablation locoregionale de tissus anormaux |
US8388955B2 (en) * | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
WO2007008232A2 (fr) * | 2004-09-03 | 2007-01-18 | Board Of Regents, The University Of Texas System | Ablation locoregionale interne de tissus anormaux par des radionucleides |
US20060067883A1 (en) * | 2004-09-24 | 2006-03-30 | Biosphere Medical, Inc. | Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof |
-
2008
- 2008-02-15 EP EP08725637A patent/EP2195036A4/fr not_active Withdrawn
- 2008-02-15 JP JP2010527928A patent/JP2010540627A/ja active Pending
- 2008-02-15 WO PCT/US2008/002026 patent/WO2009045230A1/fr active Application Filing
- 2008-02-15 CA CA2701537A patent/CA2701537A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2195036A4 (fr) | 2011-03-09 |
EP2195036A1 (fr) | 2010-06-16 |
WO2009045230A1 (fr) | 2009-04-09 |
JP2010540627A (ja) | 2010-12-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2268888T3 (es) | El uso de radio-223 para dirigirse a tejidos calcificados para paliacion del dolor y terapia de cancer oseo. | |
Farhanghi et al. | Samarium-153-EDTMP: pharmacokinetic, toxicity and pain response using an escalating dose schedule in treatment of metastatic bone cancer | |
JP5219325B2 (ja) | 骨標的錯体 | |
US10918746B2 (en) | Radioactive compositions and methods for their therapeutic use | |
AU2001267734A1 (en) | Radiotherapy | |
CA2701537A1 (fr) | Compositions pour le traitement de tumeurs par l'administration directe d'un radio-isotope | |
WO2011149844A1 (fr) | Administration de radio-isotopes thérapeutiques à fortes doses à un os | |
US20120251442A1 (en) | Methods for Treatment of Tumors by Direct Administration of a Radioisotope | |
US20090252675A1 (en) | Radionuclide Therapy for Urinary Bladder Cancer | |
US8709380B1 (en) | Targeting agents for enhancing radiation therapy |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |
Effective date: 20150317 |