CA2698814A1 - Treatment of oestrogen dependant conditions in pre-menopausal women - Google Patents

Treatment of oestrogen dependant conditions in pre-menopausal women Download PDF

Info

Publication number
CA2698814A1
CA2698814A1 CA2698814A CA2698814A CA2698814A1 CA 2698814 A1 CA2698814 A1 CA 2698814A1 CA 2698814 A CA2698814 A CA 2698814A CA 2698814 A CA2698814 A CA 2698814A CA 2698814 A1 CA2698814 A1 CA 2698814A1
Authority
CA
Canada
Prior art keywords
sts
administration
gnrh
treatment
progestin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2698814A
Other languages
English (en)
French (fr)
Inventor
Ernest Loumaye
Jean-Pierre Gotteland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Preglem SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2698814A1 publication Critical patent/CA2698814A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
CA2698814A 2007-09-17 2008-09-04 Treatment of oestrogen dependant conditions in pre-menopausal women Abandoned CA2698814A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96010907P 2007-09-17 2007-09-17
US60/960,109 2007-09-17
PCT/IB2008/002296 WO2009037539A2 (en) 2007-09-17 2008-09-04 Treatment of oestrogen dependant conditions in pre-menopausal women

Publications (1)

Publication Number Publication Date
CA2698814A1 true CA2698814A1 (en) 2009-03-26

Family

ID=40468492

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2698814A Abandoned CA2698814A1 (en) 2007-09-17 2008-09-04 Treatment of oestrogen dependant conditions in pre-menopausal women

Country Status (7)

Country Link
US (1) US20100204146A1 (enExample)
EP (1) EP2207544A2 (enExample)
JP (1) JP5543920B2 (enExample)
KR (1) KR20100068287A (enExample)
BR (1) BRPI0817045A2 (enExample)
CA (1) CA2698814A1 (enExample)
WO (1) WO2009037539A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2647378A1 (en) 2012-04-05 2013-10-09 PregLem S.A. Steroid sulfatase inhibitor regimen for the treatment of endometriosis
EP2647379A1 (en) 2012-04-05 2013-10-09 PregLem S.A. Combined use of a steroid sulfatase inhibitor for the treatment of endometriosis
BR112015023273A2 (pt) * 2013-03-14 2017-07-18 Hra Pharma Lab método para programar a ovulação.
KR101686986B1 (ko) * 2014-07-28 2016-12-16 에스케이케미칼주식회사 류프로라이드를 포함하는 속효성과 지속성을 동시에 갖는 약제학적 조성물
KR102397510B1 (ko) 2014-12-23 2022-05-13 주식회사 젬백스앤카엘 난소 기능 보존용 펩티드 및 이를 포함하는 조성물
AU2018243312B2 (en) 2017-03-31 2023-02-02 Bt Bidco, Inc. Localization systems and methods for an ingestible device
CN110809473A (zh) * 2017-06-01 2020-02-18 延世大学校产学协力团 用于预防或治疗骨相关疾病的药物组合物
WO2019110688A1 (en) * 2017-12-05 2019-06-13 Ferring B.V. A composition comprising degarelix for use in the treatment of breast cancer
WO2023150267A1 (en) * 2022-02-03 2023-08-10 Maison Amori Oqvpo Llc Methods, compositions and uses for treating cancer by providing medications that induce targeted tumor cell mitosis before providing chemotherapy or radiation and kits therefor
IT202400009064A1 (it) * 2024-04-19 2025-10-19 J Dental Care Srl Composizione per uso nel trattamento della sintomatologia post-menopausale e nel trattamento contraccettivo ormonale combinato

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
GB9118478D0 (en) 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
GB9625334D0 (en) 1996-12-05 1997-01-22 Imperial College Compound
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
GB9118465D0 (en) 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
WO1996015794A1 (en) * 1994-11-22 1996-05-30 Balance Pharmaceuticals, Inc. Compositions and methods for contraception and for treatment of benign gynecological disorders
GB9807779D0 (en) 1998-04-09 1998-06-10 Ciba Geigy Ag Organic compounds
JP4320089B2 (ja) * 1999-07-06 2009-08-26 あすか製薬株式会社 フェニルスルファメート誘導体
CO5261573A1 (es) 1999-11-19 2003-03-31 Novartis Ag Derivados de benzoxa y bezotiazol, compuesto y composicion farmaceutica que los contiene y proceso para la preparacion de la mencionada composicion
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
GB0025788D0 (en) 2000-10-20 2000-12-06 Sterix Ltd Use
WO2003006027A1 (en) * 2001-07-13 2003-01-23 Schering Aktiengesellschaft Combination of drospirenone and an estrogen sulphamate for hrt
AR037097A1 (es) 2001-10-05 2004-10-20 Novartis Ag Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
ATE319734T1 (de) 2001-10-18 2006-03-15 Sterix Ltd Steroidale verbindungen zur inhibierung von steroidsulfatasen
CN100473648C (zh) 2001-11-21 2009-04-01 斯特里克斯有限公司 作为芳香化酶抑制剂的含氨基磺酸酯基的1,2,4-三唑衍生物
AR039156A1 (es) 2002-03-28 2005-02-09 Novartis Ag Amidas del acido piperidinilamino sulfamico o piperazinil sulfamico y su uso para la manufactura de un medicamento en enfermedades mediadas por la accion de la sulfatasa esteroide
AU2003272964A1 (en) * 2002-10-09 2004-05-04 Kyowa Hakko Kogyo Co., Ltd. Remedy for hormone-dependent cancer
AR041952A1 (es) 2002-11-14 2005-06-01 Novartis Ag N-sulfonilaminotiazol
MXPA05012300A (es) * 2003-05-16 2006-01-30 Theramex Derivados de benzotiofeno de sulfamato como inhibidores de sulfatasa esteroidea.
PL1624878T3 (pl) * 2003-05-22 2007-01-31 Pantarhei Bioscience Bv Zastosowanie kompozycji zawierającej estrogenowy składnik w celu leczenia i zapobiegania bólowi mięśniowo-szkieletowemu
RU2365586C2 (ru) 2003-12-15 2009-08-27 Лаборатуар Терамекс Производные 1-n-фениламино-1н-имидазола и содержащие их фармацевтические композиции
GB0411562D0 (en) 2004-05-24 2004-06-23 Sterix Ltd Compound
GB0412492D0 (en) 2004-06-04 2004-07-07 Sterix Ltd Compound
GB0505541D0 (en) 2005-03-17 2005-04-27 Novartis Ag Organic compounds
GB0525323D0 (en) 2005-12-13 2006-01-18 Sterix Ltd Compound

Also Published As

Publication number Publication date
WO2009037539A2 (en) 2009-03-26
JP2010539153A (ja) 2010-12-16
JP5543920B2 (ja) 2014-07-09
US20100204146A1 (en) 2010-08-12
BRPI0817045A2 (pt) 2015-03-24
KR20100068287A (ko) 2010-06-22
EP2207544A2 (en) 2010-07-21
WO2009037539A3 (en) 2009-07-16

Similar Documents

Publication Publication Date Title
US20100204146A1 (en) Treatment of Oestrogen Dependant Conditions in Pre-menopausal Women
Felberbaum et al. Treatment of uterine fibroids with a slow-release formulation of the gonadotrophin releasing hormone antagonist Cetrorelix.
AU2011234587B2 (en) Parenteral pharmaceutical form which releases aromatase inhibitor and gestagens, for the treatment of endometriosis
EP2114412B1 (en) Method of treating or preventing infertility in a female mammal and pharmaceutical kit for use in such method
AU2017336338B2 (en) Methods of treating female infertility
RS21004A (sr) Upotreba hcg u kontrolisanoj hiperstimulaciji ovarijuma
Huang Medical treatment of endometriosis
AU2013236960B2 (en) Method for treating gynecological diseases
EP1455831B1 (en) Method of controlled ovarian hyperstimulation and pharmaceutical kit for use in such method
JP2012077020A (ja) ゲスターゲンとＧｎＲＨアンタゴニストとの組合せ医薬
BG106442A (bg) Мезопрогестини (прогестерон рецептор модулатори) за лечение и профилактика на хормонозависими доброкачествени гинекологични заболявания
Allan et al. Progesterone receptor agonists and antagonists
Sterrenburg et al. Drugs in reproductive medicine
Cameron et al. 5 Anti-progesterones: background and clinical physiology
US20020002153A1 (en) Pharmaceutical preparations for treating side effects during and/or after gnrha therapy
Quea et al. Letrozole administration during the luteal phase after ovarian stimulation dramatically reduces estradiol production: A randomized, placebo controlled trial
EP2647378A1 (en) Steroid sulfatase inhibitor regimen for the treatment of endometriosis

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130627

FZDE Discontinued

Effective date: 20150904