CA2671961A1 - Administration retinienne d'un acide nucleique amelioree par ionophorese - Google Patents
Administration retinienne d'un acide nucleique amelioree par ionophorese Download PDFInfo
- Publication number
- CA2671961A1 CA2671961A1 CA002671961A CA2671961A CA2671961A1 CA 2671961 A1 CA2671961 A1 CA 2671961A1 CA 002671961 A CA002671961 A CA 002671961A CA 2671961 A CA2671961 A CA 2671961A CA 2671961 A1 CA2671961 A1 CA 2671961A1
- Authority
- CA
- Canada
- Prior art keywords
- iontophoresis
- nucleic acid
- rdl
- injection
- rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87323306P | 2006-12-05 | 2006-12-05 | |
US60/873,233 | 2006-12-05 | ||
PCT/IB2007/004565 WO2008125908A2 (fr) | 2006-12-05 | 2007-12-05 | Administration rétinienne d'un acide nucléique améliorée par ionophorèse |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2671961A1 true CA2671961A1 (fr) | 2008-10-23 |
Family
ID=39864419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002671961A Abandoned CA2671961A1 (fr) | 2006-12-05 | 2007-12-05 | Administration retinienne d'un acide nucleique amelioree par ionophorese |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2099497A2 (fr) |
JP (1) | JP2010511692A (fr) |
CA (1) | CA2671961A1 (fr) |
WO (1) | WO2008125908A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009293658A1 (en) | 2008-09-22 | 2010-03-25 | James Cardia | Reduced size self-delivering RNAi compounds |
US9745574B2 (en) | 2009-02-04 | 2017-08-29 | Rxi Pharmaceuticals Corporation | RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality |
EP2550001B1 (fr) | 2010-03-24 | 2019-05-22 | Phio Pharmaceuticals Corp. | Arn interférant dans des indications oculaires |
WO2011119852A1 (fr) | 2010-03-24 | 2011-09-29 | Rxi Pharmaceuticals Corporation | Composés d'arni de taille réduite s'auto-administrant |
WO2015044704A1 (fr) * | 2013-09-30 | 2015-04-02 | Sanofi | Utilisation d'un agoniste de neuroglobuline pour prévenir ou traiter des maladies mitochondriales dues à une déficience de rcciii et/ou rcci |
WO2015168108A2 (fr) | 2014-04-28 | 2015-11-05 | Rxi Pharmaceuticals Corporation | Procédés de traitement du cancer au moyen d'un acide nucléique deciblage de mdm2 ou mycn |
JP2018502639A (ja) | 2015-01-22 | 2018-02-01 | アイゲート ファーマスーティカルズ,インコーポレイテッド | イオントフォレシスコンタクトレンズ |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030045830A1 (en) * | 2001-04-17 | 2003-03-06 | De Bizemont Therese | Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis |
JP2007532662A (ja) * | 2004-04-13 | 2007-11-15 | (オーエスアイ)アイテツク・インコーポレーテツド | 高分子量の立体的な基へ抱合された核酸アプタマー |
WO2006072887A1 (fr) * | 2005-01-05 | 2006-07-13 | Eyegate Pharma Sa | Dispositif d'iontophorese oculaire distribuant du petit arn interferent et des aptameres |
-
2007
- 2007-12-05 EP EP07873352A patent/EP2099497A2/fr not_active Withdrawn
- 2007-12-05 WO PCT/IB2007/004565 patent/WO2008125908A2/fr active Application Filing
- 2007-12-05 CA CA002671961A patent/CA2671961A1/fr not_active Abandoned
- 2007-12-05 JP JP2009539834A patent/JP2010511692A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2099497A2 (fr) | 2009-09-16 |
JP2010511692A (ja) | 2010-04-15 |
WO2008125908A2 (fr) | 2008-10-23 |
WO2008125908A3 (fr) | 2009-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20090088721A1 (en) | Enhanced retinal delivery of a nucleic acid through iontophoresis | |
Bloquel et al. | Non-viral ocular gene therapy: potential ocular therapeutic avenues | |
JP5000638B2 (ja) | 対象の眼球に対して治療用生成物を送達するための改良型方法及び装置 | |
Andrieu-Soler et al. | Ocular gene therapy: a review of nonviral strategies | |
Rossmiller et al. | Gene therapy in animal models of autosomal dominant retinitis pigmentosa | |
US20090011040A1 (en) | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases | |
CA2671961A1 (fr) | Administration retinienne d'un acide nucleique amelioree par ionophorese | |
Hao et al. | Gene delivery to cornea | |
US20210290433A1 (en) | Intraocular delivery of gene therapy expression vectors | |
US20030045830A1 (en) | Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis | |
Asahara et al. | Induction of gene into the rabbit eye by iontophoresis: preliminary report | |
Isaka | Gene therapy targeting kidney diseases: routes and vehicles | |
US11883541B2 (en) | Nonviral gene transfer to the suprachoroidal space | |
US11752220B2 (en) | Method of delivering genes and drugs to a posterior segment of an eye | |
WO2011017313A1 (fr) | Procédé d'administration de vecteurs d'acide nucléique non viraux à l'il | |
EP2418279A1 (fr) | Composition pharmaceutique injectable pour prévenir, stabiliser et/ou inhiber des états liés à une néovascularisation pathologique | |
WO2023165583A1 (fr) | Système et procédé d'administration ciblant une cellule oculaire | |
US20220273694A1 (en) | Compositions and methods for decreasing intraocular pressure | |
US20240156638A1 (en) | Devices and methods for electrotransfer | |
US11981911B2 (en) | Compositions and methods for inhibiting viral vector-induced inflammatory responses | |
US9315829B2 (en) | Methods for intracellular delivery of nucleic acids | |
WO2024064608A2 (fr) | Vecteurs de best1 et leurs utilisations | |
US20200270637A1 (en) | Compositions and methods for inhibiting viral vector-induced inflammatory responses | |
AU721060B2 (en) | Hyaluronic acid as DNA carrier for gene therapy and VEGF antisense DNA to treat abnormal retinal vascularization | |
Shukla et al. | Site-Specific Ocular Nucleic Acid Delivery |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |