CA2657532C - Methods for treating pain and screening analgesic compounds - Google Patents
Methods for treating pain and screening analgesic compounds Download PDFInfo
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- CA2657532C CA2657532C CA2657532A CA2657532A CA2657532C CA 2657532 C CA2657532 C CA 2657532C CA 2657532 A CA2657532 A CA 2657532A CA 2657532 A CA2657532 A CA 2657532A CA 2657532 C CA2657532 C CA 2657532C
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/944—Acetylcholine
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Zoology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
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- Analytical Chemistry (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83146806P | 2006-07-18 | 2006-07-18 | |
| US60/831,468 | 2006-07-18 | ||
| PCT/US2007/016163 WO2008011006A2 (en) | 2006-07-18 | 2007-07-17 | Methods for treating pain and screening analgesic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2657532A1 CA2657532A1 (en) | 2008-01-24 |
| CA2657532C true CA2657532C (en) | 2019-06-18 |
Family
ID=38957314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2657532A Expired - Fee Related CA2657532C (en) | 2006-07-18 | 2007-07-17 | Methods for treating pain and screening analgesic compounds |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9717775B2 (https=) |
| EP (1) | EP2051726B1 (https=) |
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| AU (1) | AU2007275764B2 (https=) |
| CA (1) | CA2657532C (https=) |
| WO (1) | WO2008011006A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5558817B2 (ja) | 2006-07-18 | 2014-07-23 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 痛みの処置方法および鎮痛化合物のスクリーニング方法 |
| US9284358B2 (en) * | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
| CN105377286B (zh) | 2013-05-31 | 2021-07-02 | 犹他大学研究基金会 | 芋螺毒素(conotoxin)肽，其医药组合物和用途 |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| WO2020138948A2 (ko) * | 2018-12-26 | 2020-07-02 | 아미코젠주식회사 | 아세틸콜린 수용체 저해 펩타이드 및 이의 용도 |
| CR20210363A (es) * | 2019-01-04 | 2021-12-10 | Kineta Chronic Pain Llc | Análogos de péptidos de canotoxina y usos para el tratamiento del dolor y de las afecciones inflamatorias |
| US11612661B2 (en) | 2019-01-04 | 2023-03-28 | Kineta Chronic Pain, Llc | Conotoxin peptide analogs and uses for the treatment of pain and inflammatory conditions |
| EP3969468A1 (en) * | 2019-05-17 | 2022-03-23 | Janssen Pharmaceutica NV | Expression systems for the alpha 9/alpha 10 nicotinic acetylcholine receptor and methods of use thereof |
| CN113493502B (zh) * | 2020-04-01 | 2023-09-12 | 广西大学 | α-芋螺毒素肽TxIE、其药物组合物及用途 |
| JP7715435B2 (ja) * | 2021-07-27 | 2025-07-30 | スキンメドカンパニーリミテッド | アセチルコリン受容体結合最適化短縮ペプチド及びその用途 |
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| US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
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| DE3829752A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration |
| DE3829766A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
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| CA2109085C (en) | 1991-04-25 | 2003-03-11 | Keith E. Dionne | Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products |
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| ATE190633T1 (de) | 1993-04-27 | 2000-04-15 | Cytotherapeutics Inc | Membran aus einem acrylnitrilpolymer |
| AU688776B2 (en) | 1993-06-23 | 1998-03-19 | Brown University Research Foundation | Method and apparatus for sealing implantable, membrane encapsulation devices |
| ATE218893T1 (de) | 1993-08-12 | 2002-06-15 | Neurotech Sa | Biokompatible immunoisolatorische kapseln, die genetisch veränderte zellen enthalten |
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| AU7204996A (en) | 1995-10-02 | 1997-04-28 | Cytotherapeutics, Inc. | Method for treating amyotrophic lateral sclerosis |
| AU2430897A (en) * | 1996-03-26 | 1997-10-17 | Regents Of The University Of California, The | Selective target cell activation by expression of a g protein-coupled receptor activated superiorly by synthetic ligand |
| US5844077A (en) | 1997-04-28 | 1998-12-01 | Cytotherapeutics, Inc. | Use of conantokins for producing analgesia or for neuroprotection |
| WO1999033482A1 (en) * | 1997-12-31 | 1999-07-08 | University Of Utah Research Foundation | Uses of alpha-conotoxin peptides |
| JP2002534996A (ja) | 1999-01-29 | 2002-10-22 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション | アルファ−コノトキシン・ペプチド |
| AU3473800A (en) * | 1999-01-29 | 2000-08-18 | University Of Utah Research Foundation | Conotoxin peptides |
| AU780460B2 (en) | 1999-09-15 | 2005-03-24 | Janssen Pharmaceutica N.V. | Nicotinic acetylcholine receptor alpha10 subunit |
| EP1090991A1 (en) * | 1999-09-29 | 2001-04-11 | Sanofi-Synthelabo | Novel nicotinic acetylcholine receptor subunit, its isolation and use |
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| AUPR409401A0 (en) | 2001-03-29 | 2001-04-26 | University Of Melbourne, The | Analgesic compound |
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| AU2006236006B2 (en) * | 2006-04-13 | 2012-09-06 | The University Of Queensland | Cyclised a-conotoxin peptides |
| JP5558817B2 (ja) * | 2006-07-18 | 2014-07-23 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | 痛みの処置方法および鎮痛化合物のスクリーニング方法 |
| US9284358B2 (en) | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
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2007
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- 2007-07-17 US US12/307,953 patent/US9717775B2/en active Active - Reinstated
- 2007-07-17 CA CA2657532A patent/CA2657532C/en not_active Expired - Fee Related
- 2007-07-17 EP EP07796903.8A patent/EP2051726B1/en not_active Not-in-force
- 2007-07-17 WO PCT/US2007/016163 patent/WO2008011006A2/en not_active Ceased
- 2007-07-17 AU AU2007275764A patent/AU2007275764B2/en not_active Ceased
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2014
- 2014-06-05 JP JP2014116680A patent/JP5953338B2/ja not_active Expired - Fee Related
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|---|---|
| AU2007275764B2 (en) | 2013-11-14 |
| WO2008011006A2 (en) | 2008-01-24 |
| JP2014210784A (ja) | 2014-11-13 |
| AU2007275764A1 (en) | 2008-01-24 |
| EP2051726A4 (en) | 2012-06-20 |
| WO2008011006A3 (en) | 2008-06-19 |
| JP2009545526A (ja) | 2009-12-24 |
| US20090203616A1 (en) | 2009-08-13 |
| JP5953338B2 (ja) | 2016-07-20 |
| EP2051726B1 (en) | 2018-04-18 |
| US9717775B2 (en) | 2017-08-01 |
| CA2657532A1 (en) | 2008-01-24 |
| EP2051726A2 (en) | 2009-04-29 |
| JP5558817B2 (ja) | 2014-07-23 |
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