CA2657532C - Methods for treating pain and screening analgesic compounds - Google Patents
Methods for treating pain and screening analgesic compounds Download PDFInfo
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- CA2657532C CA2657532C CA2657532A CA2657532A CA2657532C CA 2657532 C CA2657532 C CA 2657532C CA 2657532 A CA2657532 A CA 2657532A CA 2657532 A CA2657532 A CA 2657532A CA 2657532 C CA2657532 C CA 2657532C
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/944—Acetylcholine
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
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- Molecular Biology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
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- Neurosurgery (AREA)
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- Pain & Pain Management (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83146806P | 2006-07-18 | 2006-07-18 | |
| US60/831,468 | 2006-07-18 | ||
| PCT/US2007/016163 WO2008011006A2 (en) | 2006-07-18 | 2007-07-17 | Methods for treating pain and screening analgesic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2657532A1 CA2657532A1 (en) | 2008-01-24 |
| CA2657532C true CA2657532C (en) | 2019-06-18 |
Family
ID=38957314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2657532A Expired - Fee Related CA2657532C (en) | 2006-07-18 | 2007-07-17 | Methods for treating pain and screening analgesic compounds |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9717775B2 (https=) |
| EP (1) | EP2051726B1 (https=) |
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| AU (1) | AU2007275764B2 (https=) |
| CA (1) | CA2657532C (https=) |
| WO (1) | WO2008011006A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007275764B2 (en) * | 2006-07-18 | 2013-11-14 | University Of Utah Research Foundation | Methods for treating pain and screening analgesic compounds |
| US9284358B2 (en) * | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
| JP6681826B2 (ja) * | 2013-05-31 | 2020-04-15 | ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション | コノトキシンペプチド、医薬組成物およびそれらの使用 |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| CN118307629A (zh) * | 2018-12-26 | 2024-07-09 | 思亲美有限公司 | 乙酰胆碱受体抑制肽及其用途 |
| JP2022522935A (ja) * | 2019-01-04 | 2022-04-21 | キネタ・クロニック・ペイン・リミテッド・ライアビリティ・カンパニー | 疼痛および炎症状態を処置するためのコノトキシンペプチドアナログおよび使用 |
| US11612661B2 (en) | 2019-01-04 | 2023-03-28 | Kineta Chronic Pain, Llc | Conotoxin peptide analogs and uses for the treatment of pain and inflammatory conditions |
| WO2020234179A1 (en) * | 2019-05-17 | 2020-11-26 | Janssen Pharmaceutica Nv | Expression systems for the alpha 9/alpha 10 nicotinic acetylcholine receptor and methods of use thereof |
| CN113493502B (zh) * | 2020-04-01 | 2023-09-12 | 广西大学 | α-芋螺毒素肽TxIE、其药物组合物及用途 |
| US20250011363A1 (en) * | 2021-07-27 | 2025-01-09 | Skinmed Co., Ltd. | Optimized shortened peptide that binds to acetylcholine receptor, and use thereof |
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| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| US5158881A (en) | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
| DE3829752A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration |
| DE3829766A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
| US5082670A (en) | 1988-12-15 | 1992-01-21 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system |
| US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
| ATE156344T1 (de) | 1991-04-25 | 1997-08-15 | Univ Brown Res Found | Implantierbare, biokompatible immunisolator- trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte |
| US5854217A (en) | 1992-09-28 | 1998-12-29 | Bearsden Bio, Inc. | Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function |
| DK0746582T3 (da) | 1993-04-27 | 2000-08-21 | Cytotherapeutics Inc | Membran dannet af en acrylonitril-baseret polymer |
| NZ269041A (en) | 1993-06-23 | 1998-02-26 | Univ Brown Res Found | Implantable encapsulation device having a cell-tight dry seal at an opening thereof |
| SG48813A1 (en) | 1993-08-12 | 1998-05-18 | Cytotherapeutics Inc | Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules |
| US5550050A (en) | 1994-04-15 | 1996-08-27 | Cytotherapeutics, Inc. | Method for implanting encapsulated cells in a host |
| US5834029A (en) | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| US5795790A (en) | 1994-07-20 | 1998-08-18 | Cytotherapeutics, Inc. | Method for controlling proliferation and differentiation of cells encapsulated within bioartificial organs |
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| AU7204996A (en) | 1995-10-02 | 1997-04-28 | Cytotherapeutics, Inc. | Method for treating amyotrophic lateral sclerosis |
| EP0893950A4 (en) * | 1996-03-26 | 2002-02-27 | Univ California | SELECTIVE TARGET CELL ACTIVATION BY EXPRESSION OF A RECEPTOR SPECIFICALLY ACTIVATED BY SYNTHETIC LIGANDS |
| US5844077A (en) | 1997-04-28 | 1998-12-01 | Cytotherapeutics, Inc. | Use of conantokins for producing analgesia or for neuroprotection |
| AU2091799A (en) * | 1997-12-31 | 1999-07-19 | University Of Utah Research Foundation | Uses of alpha-conotoxin peptides |
| JP2002534996A (ja) * | 1999-01-29 | 2002-10-22 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション | アルファ−コノトキシン・ペプチド |
| AU3473800A (en) * | 1999-01-29 | 2000-08-18 | University Of Utah Research Foundation | Conotoxin peptides |
| KR20020059331A (ko) * | 1999-09-15 | 2002-07-12 | 디르크 반테 | 니코틴성 아세틸콜린 수용체 |
| EP1090991A1 (en) * | 1999-09-29 | 2001-04-11 | Sanofi-Synthelabo | Novel nicotinic acetylcholine receptor subunit, its isolation and use |
| US20030109670A1 (en) * | 2001-02-09 | 2003-06-12 | University Of Utah Research Foundation | Cone snail peptides |
| AUPR409401A0 (en) * | 2001-03-29 | 2001-04-26 | University Of Melbourne, The | Analgesic compound |
| EP1919506A1 (en) * | 2005-08-02 | 2008-05-14 | Metabolic Pharmaceuticals Ltd. | Peptide conjugate for oral delivery of hydrophilic peptide analgesics |
| AU2006236006B2 (en) * | 2006-04-13 | 2012-09-06 | The University Of Queensland | Cyclised a-conotoxin peptides |
| AU2007275764B2 (en) * | 2006-07-18 | 2013-11-14 | University Of Utah Research Foundation | Methods for treating pain and screening analgesic compounds |
| US9284358B2 (en) | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
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2007
- 2007-07-17 AU AU2007275764A patent/AU2007275764B2/en not_active Ceased
- 2007-07-17 JP JP2009520801A patent/JP5558817B2/ja not_active Expired - Fee Related
- 2007-07-17 CA CA2657532A patent/CA2657532C/en not_active Expired - Fee Related
- 2007-07-17 EP EP07796903.8A patent/EP2051726B1/en not_active Not-in-force
- 2007-07-17 WO PCT/US2007/016163 patent/WO2008011006A2/en not_active Ceased
- 2007-07-17 US US12/307,953 patent/US9717775B2/en active Active - Reinstated
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2009545526A (ja) | 2009-12-24 |
| JP2014210784A (ja) | 2014-11-13 |
| EP2051726A2 (en) | 2009-04-29 |
| AU2007275764A1 (en) | 2008-01-24 |
| EP2051726B1 (en) | 2018-04-18 |
| JP5953338B2 (ja) | 2016-07-20 |
| JP5558817B2 (ja) | 2014-07-23 |
| US9717775B2 (en) | 2017-08-01 |
| EP2051726A4 (en) | 2012-06-20 |
| AU2007275764B2 (en) | 2013-11-14 |
| WO2008011006A2 (en) | 2008-01-24 |
| US20090203616A1 (en) | 2009-08-13 |
| WO2008011006A3 (en) | 2008-06-19 |
| CA2657532A1 (en) | 2008-01-24 |
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