CA2655267A1 - Pyrazolopyrimidones - Google Patents

Pyrazolopyrimidones Download PDF

Info

Publication number
CA2655267A1
CA2655267A1 CA002655267A CA2655267A CA2655267A1 CA 2655267 A1 CA2655267 A1 CA 2655267A1 CA 002655267 A CA002655267 A CA 002655267A CA 2655267 A CA2655267 A CA 2655267A CA 2655267 A1 CA2655267 A1 CA 2655267A1
Authority
CA
Canada
Prior art keywords
methyl
propyl
benzyl
pyrazolo
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002655267A
Other languages
English (en)
Inventor
Thomas Maier
Thomas Baer
Andreas Lindenmaier
Matthias Vennemann
Juergen Braunger
Markus Boehm
Volker Gekeler
Astrid Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
4SC AG
Original Assignee
4Sc Ag
Thomas Maier
Thomas Baer
Andreas Lindenmaier
Matthias Vennemann
Juergen Braunger
Markus Boehm
Volker Gekeler
Astrid Zimmermann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4Sc Ag, Thomas Maier, Thomas Baer, Andreas Lindenmaier, Matthias Vennemann, Juergen Braunger, Markus Boehm, Volker Gekeler, Astrid Zimmermann filed Critical 4Sc Ag
Publication of CA2655267A1 publication Critical patent/CA2655267A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002655267A 2006-06-14 2007-06-13 Pyrazolopyrimidones Abandoned CA2655267A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06115504 2006-06-14
EP06115504.0 2006-06-14
PCT/EP2007/055846 WO2007144384A1 (fr) 2006-06-14 2007-06-13 Pyrazolopyrimidones

Publications (1)

Publication Number Publication Date
CA2655267A1 true CA2655267A1 (fr) 2007-12-21

Family

ID=37044787

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002655267A Abandoned CA2655267A1 (fr) 2006-06-14 2007-06-13 Pyrazolopyrimidones

Country Status (5)

Country Link
EP (1) EP2035426A1 (fr)
JP (1) JP2009539936A (fr)
AU (1) AU2007260040A1 (fr)
CA (1) CA2655267A1 (fr)
WO (1) WO2007144384A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE486878T1 (de) 2004-08-18 2010-11-15 4Sc Ag Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesin
JP5349056B2 (ja) 2006-02-22 2013-11-20 ４エスツェー アクチェンゲゼルシャフト Ｅｇ５キネシンモジュレーターとしてのインドロピリジン類
JP6171003B2 (ja) 2012-05-24 2017-07-26 ノバルティス アーゲー ピロロピロリジノン化合物
US9556180B2 (en) 2013-01-22 2017-01-31 Novartis Ag Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction
WO2014115077A1 (fr) * 2013-01-22 2014-07-31 Novartis Ag Composés de purinone substitués
WO2014118099A1 (fr) 2013-01-30 2014-08-07 Basf Se Naphtoquinones fongicides et dérivés
JP6373978B2 (ja) 2013-05-27 2018-08-15 ノバルティス アーゲー イミダゾピロリジノン誘導体および疾患の処置におけるその使用
AU2014272700B2 (en) 2013-05-28 2016-12-01 Novartis Ag Pyrazolo-pyrrolidin-4-one derivatives and their use in the treatment of disease
US9624247B2 (en) 2013-05-28 2017-04-18 Novartis Ag Pyrazolo-pyrrolidin-4-one derivatives as bet inhibitors and their use in the treatment of disease
CA2931249A1 (fr) 2013-11-21 2015-05-28 Novartis Ag Derives de pyrrolopyrrolone et leur utilisation en tant qu'inhibiteurs de proteines bet
CN114957261B (zh) * 2022-05-17 2023-06-23 重庆文理学院 一种具有抗头颈癌作用的化合物及其制备方法和应用
WO2024042480A1 (fr) 2022-08-26 2024-02-29 Suven Life Sciences Limited Composés hétéroaromatiques pour le traitement de troubles neurologiques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022850B2 (en) * 2003-05-22 2006-04-04 Bristol-Myers Squibb Co. Bicyclicpyrimidones and their use to treat diseases

Also Published As

Publication number Publication date
JP2009539936A (ja) 2009-11-19
EP2035426A1 (fr) 2009-03-18
AU2007260040A1 (en) 2007-12-21
WO2007144384A1 (fr) 2007-12-21

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Legal Events

Date Code Title Description
FZDE Dead

Effective date: 20130613