CA2653681A1 - Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivatives and their medical use - Google Patents
Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivatives and their medical use Download PDFInfo
- Publication number
- CA2653681A1 CA2653681A1 CA002653681A CA2653681A CA2653681A1 CA 2653681 A1 CA2653681 A1 CA 2653681A1 CA 002653681 A CA002653681 A CA 002653681A CA 2653681 A CA2653681 A CA 2653681A CA 2653681 A1 CA2653681 A1 CA 2653681A1
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- Canada
- Prior art keywords
- diaza
- bicyclo
- alkyl
- carbonyl
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80902306P | 2006-05-30 | 2006-05-30 | |
| US60/809,023 | 2006-05-30 | ||
| DKPA200600730 | 2006-05-30 | ||
| DKPA200600730 | 2006-05-30 | ||
| PCT/EP2007/055170 WO2007138039A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivatives and their medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2653681A1 true CA2653681A1 (en) | 2007-12-06 |
Family
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002653681A Abandoned CA2653681A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivatives and their medical use |
| CA002653460A Abandoned CA2653460A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its medical use |
| CA002653371A Abandoned CA2653371A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its medical use |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002653460A Abandoned CA2653460A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its medical use |
| CA002653371A Abandoned CA2653371A1 (en) | 2006-05-30 | 2007-05-29 | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its medical use |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7915272B2 (enExample) |
| EP (3) | EP2029595B1 (enExample) |
| JP (3) | JP2009538870A (enExample) |
| AU (3) | AU2007267177A1 (enExample) |
| CA (3) | CA2653681A1 (enExample) |
| MX (3) | MX2008014890A (enExample) |
| WO (3) | WO2007138041A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1713487B1 (en) * | 2004-02-04 | 2009-12-02 | Neurosearch A/S | Diazabicyclic aryl derivatives as cholinergic receptor modulators |
| MX2008014890A (es) * | 2006-05-30 | 2008-12-05 | Neurosearch As | Nuevos derivados de 1,4-diaza-biciclo[3.2.2]nonil pirimidinilo y su uso medico. |
| JP2010536726A (ja) * | 2007-08-17 | 2010-12-02 | ノイロサーチ アクティーゼルスカブ | ニコチン性アセチルコリン受容体リガンドとして有用な新規１，４−ジアザ−ビシクロ〔３．２．２〕ノニルヘテロアリール誘導体 |
| DE102007053771A1 (de) * | 2007-11-12 | 2009-05-14 | Merck Patent Gmbh | Organische Elektrolumineszenzvorrichtungen |
| BRPI0820259A2 (pt) * | 2007-11-14 | 2015-06-16 | Neurosearch As | Derivado de 1,4-diaza-biciclo[3.2.2] nonil pirimidina, composição farmacêutica, uso do derivado de 1,4-diaza-biciclo[3.2.2] nonil pirimidina, e, método de tratamento, prevenção ou alívio de uma doença ou uma desordem ou uma condição de um corpo de animal vivo |
| US20100305108A1 (en) * | 2007-11-14 | 2010-12-02 | Neurosearch A/S | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidine derivatives and their medical use |
| JP2011503144A (ja) * | 2007-11-14 | 2011-01-27 | ノイロサーチ アクティーゼルスカブ | 新規の１，４−ジアザ−ビシクロ［３．２．２］ノニルピリミジン誘導体及びその医療への使用 |
| WO2010026176A1 (en) * | 2008-09-05 | 2010-03-11 | Neurosearch A/S | 1,4 -diaza- bicyclo [3.2.2]n0nyl pyrimidine derivatives as nicotinic and monoamine receptor modulators |
| WO2010026177A1 (en) * | 2008-09-05 | 2010-03-11 | Neurosearch A/S | 1,4-diaza-bicyclo [3.2.2] nonyl pyridine derivatives as nicotinic and monoamine receptor modulators |
| US20110269778A1 (en) * | 2008-10-10 | 2011-11-03 | Neurosearch A/S | Novel diphenyl purine derivatives useful as modulators of nicotinic acetylcholine receptors |
| US20110257161A1 (en) * | 2008-12-04 | 2011-10-20 | Neurosearch A/S | Novel diaza-bicyclononyl-phenyl derivatives and their medical use |
| US20120004214A1 (en) * | 2009-01-21 | 2012-01-05 | Neurosearch A/S | N-oxides of 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivatives useful as nicotinic acetylcholine receptor ligands |
| US20120028967A1 (en) * | 2009-01-21 | 2012-02-02 | Neurosearch A/S | Novel diaza-bicyclononyl-pyrimidinyl derivatives and their medical use |
| JO3250B1 (ar) | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2786770B1 (fr) * | 1998-12-04 | 2001-01-19 | Synthelabo | Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique |
| JP2004518723A (ja) * | 2001-02-14 | 2004-06-24 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | ピリミジンマトリックスメタロプロテイナーゼ阻害剤 |
| WO2002100399A1 (en) * | 2001-06-12 | 2002-12-19 | Elan Pharmaceuticals, Inc. | Macrocycles useful in the treatment of alzheimer's disease |
| SE0202430D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | New Compounds |
| WO2004024729A1 (en) | 2002-09-10 | 2004-03-25 | Pfizer Products Inc. | Diazabicyclic compounds useful in the treatment of cns and other disorders |
| ATE353899T1 (de) | 2002-09-30 | 2007-03-15 | Neurosearch As | Neue 1,4-diazabicycloalkanderivate, deren herstellung und verwendung |
| EP1562945B1 (en) | 2002-11-11 | 2006-11-15 | Neurosearch A/S | 1,4-diazabicyclo(3,2,2)nonane derivatives, preparation and therapeutical use thereof |
| US7223753B2 (en) | 2002-11-11 | 2007-05-29 | Neurosearch A/S | Diazabicyclic biaryl derivatives |
| EP1713487B1 (en) | 2004-02-04 | 2009-12-02 | Neurosearch A/S | Diazabicyclic aryl derivatives as cholinergic receptor modulators |
| CA2555311A1 (en) | 2004-02-04 | 2005-08-18 | Neurosearch A/S | Diazabicyclic aryl derivatives as nicotinic acetylcholine receptor ligands |
| WO2006087306A2 (en) | 2005-02-16 | 2006-08-24 | Neurosearch A/S | Diazabicyclic aryl derivatives and their use as cholinergic ligands at the nicotinic acetylcholine receptors |
| MX2008014890A (es) | 2006-05-30 | 2008-12-05 | Neurosearch As | Nuevos derivados de 1,4-diaza-biciclo[3.2.2]nonil pirimidinilo y su uso medico. |
| WO2009024515A1 (en) | 2007-08-17 | 2009-02-26 | Neurosearch A/S | 1,4-diaza-bicycl0(3.2.2)n0nyl pyrimidinyl derivatives useful as nicotinic acetylcholine- receptor ligands |
| JP2010536726A (ja) | 2007-08-17 | 2010-12-02 | ノイロサーチ アクティーゼルスカブ | ニコチン性アセチルコリン受容体リガンドとして有用な新規１，４−ジアザ−ビシクロ〔３．２．２〕ノニルヘテロアリール誘導体 |
| JP2011503144A (ja) * | 2007-11-14 | 2011-01-27 | ノイロサーチ アクティーゼルスカブ | 新規の１，４−ジアザ−ビシクロ［３．２．２］ノニルピリミジン誘導体及びその医療への使用 |
| US20100305108A1 (en) * | 2007-11-14 | 2010-12-02 | Neurosearch A/S | Novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidine derivatives and their medical use |
-
2007
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- 2007-05-29 EP EP07729594A patent/EP2029595B1/en not_active Not-in-force
- 2007-05-29 US US12/299,114 patent/US7915272B2/en not_active Expired - Fee Related
- 2007-05-29 WO PCT/EP2007/055172 patent/WO2007138041A1/en not_active Ceased
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- 2007-05-29 WO PCT/EP2007/055170 patent/WO2007138039A1/en not_active Ceased
- 2007-05-29 EP EP07729593A patent/EP2049538A1/en not_active Withdrawn
- 2007-05-29 AU AU2007267177A patent/AU2007267177A1/en not_active Abandoned
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- 2007-05-29 JP JP2009512570A patent/JP2009538868A/ja not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007138041A1 (en) | 2007-12-06 |
| WO2007138041A8 (en) | 2008-11-20 |
| MX2008014885A (es) | 2008-12-05 |
| AU2007267176A1 (en) | 2007-12-06 |
| JP2009538869A (ja) | 2009-11-12 |
| JP2009538870A (ja) | 2009-11-12 |
| WO2007138040A1 (en) | 2007-12-06 |
| US20090197872A1 (en) | 2009-08-06 |
| US20090270403A1 (en) | 2009-10-29 |
| AU2007267178A1 (en) | 2007-12-06 |
| CA2653371A1 (en) | 2007-12-06 |
| WO2007138039A1 (en) | 2007-12-06 |
| MX2008014890A (es) | 2008-12-05 |
| US8148365B2 (en) | 2012-04-03 |
| EP2049538A1 (en) | 2009-04-22 |
| WO2007138040A8 (en) | 2008-11-20 |
| US20090181984A1 (en) | 2009-07-16 |
| MX2008014889A (es) | 2008-12-05 |
| EP2041134A1 (en) | 2009-04-01 |
| CA2653460A1 (en) | 2007-12-06 |
| US7915272B2 (en) | 2011-03-29 |
| JP2009538868A (ja) | 2009-11-12 |
| EP2029595A1 (en) | 2009-03-04 |
| EP2029595B1 (en) | 2011-09-21 |
| AU2007267177A1 (en) | 2007-12-06 |
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