CA2653485A1 - Formulations de sel de prednisolone - Google Patents
Formulations de sel de prednisolone Download PDFInfo
- Publication number
- CA2653485A1 CA2653485A1 CA002653485A CA2653485A CA2653485A1 CA 2653485 A1 CA2653485 A1 CA 2653485A1 CA 002653485 A CA002653485 A CA 002653485A CA 2653485 A CA2653485 A CA 2653485A CA 2653485 A1 CA2653485 A1 CA 2653485A1
- Authority
- CA
- Canada
- Prior art keywords
- dosage form
- sodium phosphate
- prednisolone sodium
- prednisolone
- dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000003117 prednisolones Chemical class 0.000 title abstract description 22
- 239000000203 mixture Substances 0.000 title description 44
- 238000009472 formulation Methods 0.000 title description 27
- 229960005205 prednisolone Drugs 0.000 claims abstract description 35
- 239000002245 particle Substances 0.000 claims description 130
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- 229960002943 prednisolone sodium phosphate Drugs 0.000 claims description 88
- 239000000463 material Substances 0.000 claims description 60
- 210000000214 mouth Anatomy 0.000 claims description 35
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 claims description 35
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 24
- 241000282412 Homo Species 0.000 claims description 12
- 239000007787 solid Substances 0.000 claims description 11
- 230000001747 exhibiting effect Effects 0.000 claims description 6
- JDOZJEUDSLGTLU-VWUMJDOOSA-N prednisolone phosphate Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)COP(O)(O)=O)[C@@H]4[C@@H]3CCC2=C1 JDOZJEUDSLGTLU-VWUMJDOOSA-N 0.000 claims 27
- 239000003826 tablet Substances 0.000 abstract description 144
- -1 prednisolone sodium phosphates Chemical class 0.000 abstract description 15
- 239000007938 effervescent tablet Substances 0.000 abstract description 6
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- VJZLQIPZNBPASX-OJJGEMKLSA-L prednisolone sodium phosphate Chemical compound [Na+].[Na+].O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)COP([O-])([O-])=O)[C@@H]4[C@@H]3CCC2=C1 VJZLQIPZNBPASX-OJJGEMKLSA-L 0.000 description 88
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81001506P | 2006-06-01 | 2006-06-01 | |
| US60/810,015 | 2006-06-01 | ||
| US11/638,260 | 2006-12-13 | ||
| US11/638,216 | 2006-12-13 | ||
| US11/638,260 US20070281014A1 (en) | 2006-06-01 | 2006-12-13 | Prednisolone salt formulations |
| US11/638,216 US8637076B2 (en) | 2006-06-01 | 2006-12-13 | Prednisolone salt formulations |
| PCT/US2007/013008 WO2007143131A2 (fr) | 2006-06-01 | 2007-05-30 | Formulations de sel de prédnisolone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2653485A1 true CA2653485A1 (fr) | 2007-12-13 |
Family
ID=38616310
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002653485A Abandoned CA2653485A1 (fr) | 2006-06-01 | 2007-05-30 | Formulations de sel de prednisolone |
| CA002653480A Abandoned CA2653480A1 (fr) | 2006-06-01 | 2007-05-31 | Formules de sels de prednisolone |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002653480A Abandoned CA2653480A1 (fr) | 2006-06-01 | 2007-05-31 | Formules de sels de prednisolone |
Country Status (3)
| Country | Link |
|---|---|
| CA (2) | CA2653485A1 (fr) |
| MX (2) | MX2008015059A (fr) |
| WO (2) | WO2007143131A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2926722B1 (fr) * | 2008-01-25 | 2010-09-03 | Substipharm Dev | Formulation pharmaceutique appropriee pour la preparation de comprimes orodispersibles de prednisolone |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE615854A (fr) * | ||||
| US3921636A (en) * | 1973-01-15 | 1975-11-25 | Alza Corp | Novel drug delivery device |
| US6740341B1 (en) * | 1998-11-25 | 2004-05-25 | Cima Labs Inc. | Taste masking rapid release coating system |
| CA2351720C (fr) * | 1998-11-25 | 2006-11-21 | Cima Labs Inc. | Systeme d'enrobage a liberation rapide masquant le gout |
| DE60213283T2 (de) * | 2001-12-20 | 2007-07-12 | Alpex Pharma S.A. | Pharmazeutische zusammensetzung enthaltend magermilchpulver |
| US8110223B2 (en) * | 2002-12-31 | 2012-02-07 | University Of Maryland, Baltimore | Methods for making pharmaceutical dosage forms containing active cushioning components |
| RU2382637C2 (ru) * | 2004-04-30 | 2010-02-27 | Астеллас Фарма Инк. | Фармацевтическая композиция для перорального введения в форме частиц с рассчитанным временем высвобождения и быстро распадающиеся таблетки, содержащие указанную композицию |
-
2007
- 2007-05-30 WO PCT/US2007/013008 patent/WO2007143131A2/fr active Application Filing
- 2007-05-30 MX MX2008015059A patent/MX2008015059A/es active IP Right Grant
- 2007-05-30 CA CA002653485A patent/CA2653485A1/fr not_active Abandoned
- 2007-05-31 CA CA002653480A patent/CA2653480A1/fr not_active Abandoned
- 2007-05-31 WO PCT/US2007/012883 patent/WO2007143061A2/fr active Application Filing
- 2007-05-31 MX MX2008015058A patent/MX2008015058A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007143131A3 (fr) | 2008-03-20 |
| WO2007143131A2 (fr) | 2007-12-13 |
| CA2653480A1 (fr) | 2007-12-13 |
| WO2007143131A9 (fr) | 2008-02-14 |
| WO2007143061A3 (fr) | 2008-02-14 |
| WO2007143061A2 (fr) | 2007-12-13 |
| MX2008015058A (es) | 2009-04-14 |
| MX2008015059A (es) | 2009-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20130530 |