CA2638899C - Systemes de nano-administration visant une tumeur pour ameliorer la detection precoce par irm d'un cancer - Google Patents
Systemes de nano-administration visant une tumeur pour ameliorer la detection precoce par irm d'un cancer Download PDFInfo
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- CA2638899C CA2638899C CA2638899A CA2638899A CA2638899C CA 2638899 C CA2638899 C CA 2638899C CA 2638899 A CA2638899 A CA 2638899A CA 2638899 A CA2638899 A CA 2638899A CA 2638899 C CA2638899 C CA 2638899C
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Abstract
Cette invention concerne une méthode pour fabriquer des immunoliposomes visant des fragments d'anticorps ou des anticorps pour administration systémique de molécules dans le but de traiter et de produire une image de maladies, y compris des tumeurs cancéreuses. L'invention concerne aussi des immunoliposomes et des compositions, ainsi que des méthodes d'imagerie de divers tissus. Les complexes de liposomes sont utiles pour l'encapsulation d'agents d'imagerie, par exemple, à utiliser en imagerie par résonance magnétique. La spécificité du dispositif d'administration découle du ciblage des anticorps ou des fragments d'anticorps.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72830305P | 2005-10-20 | 2005-10-20 | |
US60/728,303 | 2005-10-20 | ||
PCT/US2006/041139 WO2007047981A2 (fr) | 2005-10-20 | 2006-10-20 | Systèmes de nano-administration visant une tumeur pour améliorer la détection précoce par irm d'un cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2638899A1 CA2638899A1 (fr) | 2007-04-26 |
CA2638899C true CA2638899C (fr) | 2016-01-05 |
Family
ID=37963345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2638899A Expired - Fee Related CA2638899C (fr) | 2005-10-20 | 2006-10-20 | Systemes de nano-administration visant une tumeur pour ameliorer la detection precoce par irm d'un cancer |
Country Status (8)
Country | Link |
---|---|
JP (1) | JP5478886B2 (fr) |
KR (1) | KR20080064169A (fr) |
CN (1) | CN101351225B (fr) |
AU (1) | AU2006304790B2 (fr) |
CA (1) | CA2638899C (fr) |
HK (1) | HK1129063A1 (fr) |
IL (1) | IL190773A (fr) |
WO (1) | WO2007047981A2 (fr) |
Families Citing this family (9)
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KR101570886B1 (ko) * | 2007-07-09 | 2015-11-23 | 조지타운 유니버시티 | 양이온성-리포솜 매개된 핵산 전달을 이용하여 면역 반응을 생성시키는 방법 |
US8320647B2 (en) | 2007-11-20 | 2012-11-27 | Olea Medical | Method and system for processing multiple series of biological images obtained from a patient |
EP4241767A3 (fr) * | 2008-11-10 | 2023-11-01 | Arbutus Biopharma Corporation | Nouveaux lipides et compositions d'administration d'agents thérapeutiques |
CN102078624B (zh) * | 2010-12-23 | 2012-07-25 | 华东理工大学 | 一种高效载钆脂质体制剂及其制备方法 |
WO2013031619A1 (fr) * | 2011-08-26 | 2013-03-07 | 学校法人藤田学園 | Agent de diagnostic de tumeur à base d'image contenant un anticorps du récepteur d'anti-transferrine humaine |
CN103655475B (zh) * | 2012-09-19 | 2020-04-28 | 乔治敦大学 | 靶向的脂质体 |
US20140120157A1 (en) | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
EP2968598B1 (fr) | 2013-03-14 | 2020-05-27 | Georgetown University | Traitement après l'exposition à un agent neurotoxique |
JP2021523145A (ja) * | 2018-05-08 | 2021-09-02 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 磁性リポソームおよび関連する治療ならびにイメージング方法 |
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JP3902794B2 (ja) * | 1997-03-07 | 2007-04-11 | マックス−デルブルック−セントラム フュア モレクラーレ メディシン | 特異的磁気体、その製造方法及び使用 |
EP1811036B8 (fr) * | 1999-02-22 | 2011-09-21 | Georgetown University | Immunolipsomes ciblés sur un fragment d'anticorps utiles pour l'administration systemique d'un gène |
US7780882B2 (en) * | 1999-02-22 | 2010-08-24 | Georgetown University | Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent |
EP1278512A2 (fr) * | 2000-05-03 | 2003-01-29 | MBT Munich Biotechnology AG | Agents de diagnostic cationique, d'imagerie et de therapie associes a des sites vasculaires actives |
JP2006505498A (ja) * | 2002-04-03 | 2006-02-16 | シー,ジャッキー アール. | 病変組織の超音波イメージング及び処置方法 |
WO2004066946A2 (fr) * | 2003-01-28 | 2004-08-12 | Georgetown University | Procede pour l'evaluation de l'efficacite de certains traitements du cancer |
DK1633327T3 (da) * | 2003-06-04 | 2010-11-15 | Univ Georgetown | Fremgangsmåde til forbedring af stabilitet og opbevaringslevetid af liposomkomplekser |
EP1648299A4 (fr) * | 2003-07-09 | 2008-10-22 | California Pacific Med Center | Detection a distance de la diffusion de substances aux cellules |
JP2005170807A (ja) * | 2003-12-09 | 2005-06-30 | Fuji Photo Film Co Ltd | 抗体を含むリポソーム |
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2006
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- 2006-10-20 JP JP2008536843A patent/JP5478886B2/ja not_active Expired - Fee Related
- 2006-10-20 KR KR1020087011910A patent/KR20080064169A/ko not_active Application Discontinuation
- 2006-10-20 AU AU2006304790A patent/AU2006304790B2/en not_active Ceased
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- 2006-10-20 WO PCT/US2006/041139 patent/WO2007047981A2/fr active Application Filing
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AU2006304790A1 (en) | 2007-04-26 |
CN101351225A (zh) | 2009-01-21 |
CN101351225B (zh) | 2013-09-25 |
JP5478886B2 (ja) | 2014-04-23 |
HK1129063A1 (en) | 2009-11-20 |
IL190773A (en) | 2012-06-28 |
KR20080064169A (ko) | 2008-07-08 |
IL190773A0 (en) | 2008-11-03 |
CA2638899A1 (fr) | 2007-04-26 |
JP2009512712A (ja) | 2009-03-26 |
AU2006304790B2 (en) | 2013-06-27 |
WO2007047981A2 (fr) | 2007-04-26 |
WO2007047981A3 (fr) | 2007-10-25 |
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