CA2626209C - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

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Publication number
CA2626209C
CA2626209C CA2626209A CA2626209A CA2626209C CA 2626209 C CA2626209 C CA 2626209C CA 2626209 A CA2626209 A CA 2626209A CA 2626209 A CA2626209 A CA 2626209A CA 2626209 C CA2626209 C CA 2626209C
Authority
CA
Canada
Prior art keywords
mass
ion
ions
mass analyser
electrodes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2626209A
Other languages
English (en)
French (fr)
Other versions
CA2626209A1 (en
Inventor
Steven Derek Pringle
Jason Lee Wildgoose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of CA2626209A1 publication Critical patent/CA2626209A1/en
Application granted granted Critical
Publication of CA2626209C publication Critical patent/CA2626209C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4235—Stacked rings or stacked plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426—Methods for controlling ions
    • H01J49/427—Ejection and selection methods

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CA2626209A 2005-11-01 2006-11-01 Mass spectrometer Expired - Fee Related CA2626209C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0522327.6A GB0522327D0 (en) 2005-11-01 2005-11-01 Mass spectrometer
GB0522327.6 2005-11-01
US73505805P 2005-11-09 2005-11-09
US60/735,058 2005-11-09
PCT/GB2006/004078 WO2007052025A2 (en) 2005-11-01 2006-11-01 Mass spectrometer

Publications (2)

Publication Number Publication Date
CA2626209A1 CA2626209A1 (en) 2007-05-10
CA2626209C true CA2626209C (en) 2016-01-05

Family

ID=35516180

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2626209A Expired - Fee Related CA2626209C (en) 2005-11-01 2006-11-01 Mass spectrometer

Country Status (7)

Country Link
US (1) US9184039B2 (enExample)
EP (1) EP1943663B1 (enExample)
JP (1) JP4778560B2 (enExample)
CN (1) CN101305444B (enExample)
CA (1) CA2626209C (enExample)
GB (2) GB0522327D0 (enExample)
WO (1) WO2007052025A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12154777B2 (en) 2019-06-14 2024-11-26 Shanghai Polaris Biology Co., Ltd. Systems and methods for single particle analysis

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0514964D0 (en) * 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
GB2440613B (en) * 2005-07-21 2010-04-14 Micromass Ltd Mass spectrometer
US10309929B2 (en) * 2006-02-14 2019-06-04 Excellims Corporation Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection
US10073056B2 (en) * 2006-02-14 2018-09-11 Excellims Corporation Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection
WO2007125354A2 (en) * 2006-04-28 2007-11-08 Micromass Uk Limited Mass spectrometer
GB0608470D0 (en) * 2006-04-28 2006-06-07 Micromass Ltd Mass spectrometer
CA2656197C (en) * 2006-07-10 2015-06-16 John Brian Hoyes Mass spectrometer
JP5164478B2 (ja) * 2006-08-30 2013-03-21 株式会社日立ハイテクノロジーズ イオントラップ飛行時間型質量分析装置
US10794862B2 (en) * 2006-11-28 2020-10-06 Excellims Corp. Practical ion mobility spectrometer apparatus and methods for chemical and/or biological detection
US7964843B2 (en) 2008-07-18 2011-06-21 The George Washington University Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry
US8067730B2 (en) 2007-07-20 2011-11-29 The George Washington University Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry
US8901487B2 (en) 2007-07-20 2014-12-02 George Washington University Subcellular analysis by laser ablation electrospray ionization mass spectrometry
GB0718468D0 (en) 2007-09-21 2007-10-31 Micromass Ltd Mass spectrometer
GB0800526D0 (en) 2008-01-11 2008-02-20 Micromass Ltd Mass spectrometer
US7952070B2 (en) * 2009-01-12 2011-05-31 Thermo Finnigan Llc Interlaced Y multipole
EP2430404A4 (en) * 2009-05-11 2016-10-26 Thermo Finnigan Llc ION POPULATION CONTROL IN A MASS SPECTROMETER WITH MASS-ACTIVE TRANSMISSION OPTICS
US20110149252A1 (en) * 2009-12-21 2011-06-23 Matthew Keith Schwiebert Electrohydrodynamic Air Mover Performance
JP5890782B2 (ja) * 2009-12-23 2016-03-22 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ 携帯用質量分析のための装置および方法
US8829434B2 (en) * 2010-11-19 2014-09-09 Hitachi High-Technologies Corporation Mass spectrometer and mass spectrometry method
CA2841752A1 (en) 2011-07-14 2013-06-13 The George Washington University Plume collimation for laser ablation electrospray ionization mass spectrometry
JP2014526046A (ja) * 2011-08-05 2014-10-02 アカデミア シニカ 高速プロテオミクスのためのステップ走査式イオントラップ質量分析
US9324551B2 (en) 2012-03-16 2016-04-26 Shimadzu Corporation Mass spectrometer and method of driving ion guide
JP5870848B2 (ja) * 2012-05-28 2016-03-01 株式会社島津製作所 イオンガイド及び質量分析装置
JP6102543B2 (ja) 2013-06-17 2017-03-29 セイコーエプソン株式会社 液晶装置の駆動方法、液晶装置、電子機器
GB2541795B (en) * 2014-05-23 2018-04-11 Thermo Fisher Scient Bremen Gmbh Method and apparatus for mass spectrometry of macromolecular complexes
JP6394438B2 (ja) 2015-02-27 2018-09-26 セイコーエプソン株式会社 液晶装置及び電子機器
US20160260594A1 (en) * 2015-03-02 2016-09-08 Bayspec, Inc. Sample Inlet and Vacuum System for Portable Mass Spectrometer
CN107144626B (zh) * 2016-03-01 2019-11-05 合肥美亚光电技术股份有限公司 离子选择性光解离装置、方法以及仪器
EP3443580B1 (en) * 2016-04-14 2024-07-17 Micromass UK Limited Two-dimensional msms
CN107305833B (zh) 2016-04-25 2019-05-28 株式会社岛津制作所 离子光学装置
GB201609243D0 (en) * 2016-05-25 2016-07-06 Micromass Ltd Efficient ion tapping
GB201614540D0 (en) * 2016-08-26 2016-10-12 Micromass Ltd Controlling ion temperature in an ion guide
GB201802917D0 (en) 2018-02-22 2018-04-11 Micromass Ltd Charge detection mass spectrometry
GB201808892D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
GB201808949D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808912D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
US11367607B2 (en) 2018-05-31 2022-06-21 Micromass Uk Limited Mass spectrometer
GB201808894D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
GB201808890D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
US11373849B2 (en) 2018-05-31 2022-06-28 Micromass Uk Limited Mass spectrometer having fragmentation region
GB201808932D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808936D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808893D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
US10665441B2 (en) 2018-08-08 2020-05-26 Thermo Finnigan Llc Methods and apparatus for improved tandem mass spectrometry duty cycle
GB201819372D0 (en) * 2018-11-28 2019-01-09 Shimadzu Corp Apparatus for analysing ions
US10651025B1 (en) 2018-12-21 2020-05-12 Thermo Finnigan Llc Orthogonal-flow ion trap array
JP2019091700A (ja) * 2019-01-04 2019-06-13 ９０８ デバイセズ インク．９０８ Ｄｅｖｉｃｅｓ Ｉｎｃ． コンパクトな質量分析計
US12176196B2 (en) * 2019-02-15 2024-12-24 Ohio State Innovation Foundation Surface-induced dissociation devices and methods
GB201912489D0 (en) 2019-08-30 2019-10-16 Shimadzu Corp Mass analysis apparatuses and methods
WO2021207494A1 (en) 2020-04-09 2021-10-14 Waters Technologies Corporation Ion detector
CN113707532B (zh) * 2020-05-21 2024-12-24 株式会社岛津制作所 质谱仪、质谱方法以及检测系统
US11600480B2 (en) * 2020-09-22 2023-03-07 Thermo Finnigan Llc Methods and apparatus for ion transfer by ion bunching
GB202020575D0 (en) * 2020-12-24 2021-02-10 Micromass Ltd Characterising mixtures of high-mass particles using m/z seperation
WO2023111707A1 (en) 2021-12-15 2023-06-22 Waters Technologies Corporation An inductive detector with integrated amplifier
WO2025150190A1 (ja) * 2024-01-12 2025-07-17 株式会社島津製作所 質量分析装置

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5033895A (enExample) * 1973-07-25 1975-04-01
US4234791A (en) * 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
US5206506A (en) * 1991-02-12 1993-04-27 Kirchner Nicholas J Ion processing: control and analysis
CA2229070C (en) * 1995-08-11 2007-01-30 Mds Health Group Limited Spectrometer with axial field
GB0028586D0 (en) * 2000-11-23 2001-01-10 Univ Warwick An ion focussing and conveying device
JP2002184347A (ja) * 2000-12-12 2002-06-28 Shimadzu Corp 質量分析装置
CA2391140C (en) * 2001-06-25 2008-10-07 Micromass Limited Mass spectrometer
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
US7034292B1 (en) * 2002-05-31 2006-04-25 Analytica Of Branford, Inc. Mass spectrometry with segmented RF multiple ion guides in various pressure regions
GB0305796D0 (en) * 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
AU2003260773A1 (en) * 2002-09-03 2004-03-29 Micromass Uk Limited Mass spectrometer
US6838662B2 (en) * 2002-11-08 2005-01-04 Micromass Uk Limited Mass spectrometer
US6838666B2 (en) * 2003-01-10 2005-01-04 Purdue Research Foundation Rectilinear ion trap and mass analyzer system and method
US7459693B2 (en) * 2003-04-04 2008-12-02 Bruker Daltonics, Inc. Ion guide for mass spectrometers
GB0514964D0 (en) * 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
WO2005067000A2 (en) * 2004-01-09 2005-07-21 Ms Horizons Limited Ion extraction devices and methods of selectively extracting ions
US7026613B2 (en) 2004-01-23 2006-04-11 Thermo Finnigan Llc Confining positive and negative ions with fast oscillating electric potentials
JP4872088B2 (ja) 2004-05-05 2012-02-08 ディーエイチ テクノロジーズ ディベロップメント ピーティーイー リミテッド 質量分析計用イオンガイド
US7227130B2 (en) 2004-05-20 2007-06-05 Mds Inc. Method for providing barrier fields at the entrance and exit end of a mass spectrometer
JP4643206B2 (ja) * 2004-09-03 2011-03-02 株式会社日立ハイテクノロジーズ 質量分析装置
US7557343B2 (en) * 2005-09-13 2009-07-07 Agilent Technologies, Inc. Segmented rod multipole as ion processing cell

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12154777B2 (en) 2019-06-14 2024-11-26 Shanghai Polaris Biology Co., Ltd. Systems and methods for single particle analysis

Also Published As

Publication number Publication date
GB2434249A (en) 2007-07-18
US20090072136A1 (en) 2009-03-19
JP4778560B2 (ja) 2011-09-21
CA2626209A1 (en) 2007-05-10
GB0621787D0 (en) 2006-12-13
WO2007052025A2 (en) 2007-05-10
WO2007052025A3 (en) 2008-02-07
EP1943663B1 (en) 2018-01-17
US9184039B2 (en) 2015-11-10
CN101305444A (zh) 2008-11-12
EP1943663A2 (en) 2008-07-16
HK1120926A1 (zh) 2009-04-09
JP2009514179A (ja) 2009-04-02
GB0522327D0 (en) 2005-12-07
GB2434249B (en) 2010-06-09
CN101305444B (zh) 2011-03-16

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Effective date: 20201102