CA2624096A1 - Benzothiadiazolyphenylalkylamine derivatives for use in the treatment of conditions ameliorated by monoamine reuptake - Google Patents
Benzothiadiazolyphenylalkylamine derivatives for use in the treatment of conditions ameliorated by monoamine reuptake Download PDFInfo
- Publication number
- CA2624096A1 CA2624096A1 CA002624096A CA2624096A CA2624096A1 CA 2624096 A1 CA2624096 A1 CA 2624096A1 CA 002624096 A CA002624096 A CA 002624096A CA 2624096 A CA2624096 A CA 2624096A CA 2624096 A1 CA2624096 A1 CA 2624096A1
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- Prior art keywords
- pain
- compound according
- methyl
- alkyl
- substituted
- Prior art date
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- 238000000034 method Methods 0.000 claims abstract description 77
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 34
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- 125000004093 cyano group Chemical group *C#N 0.000 claims description 18
- 125000000623 heterocyclic group Chemical group 0.000 claims description 18
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims description 18
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- 125000004423 acyloxy group Chemical group 0.000 claims description 14
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 13
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- 125000004851 cyclopentylmethyl group Chemical group C1(CCCC1)C* 0.000 claims description 5
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 5
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- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72169305P | 2005-09-29 | 2005-09-29 | |
| US60/721,693 | 2005-09-29 | ||
| PCT/US2006/037962 WO2007041258A1 (en) | 2005-09-29 | 2006-09-27 | Benzothiadiazolyphenylalkylamine derivatives for use in the treatment of conditions ameliorated by monoamine reuptake |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2624096A1 true CA2624096A1 (en) | 2007-04-12 |
Family
ID=37684875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002624096A Abandoned CA2624096A1 (en) | 2005-09-29 | 2006-09-27 | Benzothiadiazolyphenylalkylamine derivatives for use in the treatment of conditions ameliorated by monoamine reuptake |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7601744B2 (https=) |
| EP (1) | EP1934193A1 (https=) |
| JP (1) | JP2009510095A (https=) |
| KR (1) | KR20080050453A (https=) |
| CN (1) | CN101277941A (https=) |
| AR (1) | AR055660A1 (https=) |
| AU (1) | AU2006297208A1 (https=) |
| BR (1) | BRPI0616462A2 (https=) |
| CA (1) | CA2624096A1 (https=) |
| CR (1) | CR9829A (https=) |
| EC (1) | ECSP088300A (https=) |
| GT (1) | GT200600441A (https=) |
| IL (1) | IL190273A0 (https=) |
| NO (1) | NO20081235L (https=) |
| PE (1) | PE20070544A1 (https=) |
| RU (1) | RU2008110082A (https=) |
| TW (1) | TW200804325A (https=) |
| WO (1) | WO2007041258A1 (https=) |
| ZA (1) | ZA200802774B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2007003590A1 (es) * | 2006-12-12 | 2008-02-29 | Wyeth Corp | Compuestos derivados de aril sulfamida; procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso en prevencion y tratamiento de sintomas vasomotrices, disfuncion sexual, transtornos gastrointestinales, transt |
| WO2009076502A1 (en) * | 2007-12-12 | 2009-06-18 | Wyeth | Methods for the preparation of hydroxy-substituted aryl sulfamide compounds |
| BRPI0908098A2 (pt) * | 2008-02-19 | 2015-08-18 | Adolor Corp | Beloxepina, composição, métodos para tratar dor em um mamífero, para inibir a recaptação de ne, para antagonizar um receptor de 5ht2 e para tratar um distúrbio em um paciente que é responsivo ao tratamento com um composto nri e com um composto antagonista de 5ht2 |
| US20090233959A1 (en) | 2008-02-19 | 2009-09-17 | Adolor Corporation | Beloxepin and analogs for the treatment of pain |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA200000890A1 (ru) | 1998-03-02 | 2001-02-26 | Эли Лилли Энд Компани | Гидрохлорид флуоксетина для уменьшения "приливов" (приступообразных ощущений жара (при климактерическом синдроме)) |
| EP1587781A1 (en) | 2002-11-05 | 2005-10-26 | Eli Lilly And Company | 3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake |
| US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
-
2006
- 2006-09-27 PE PE2006001171A patent/PE20070544A1/es not_active Application Discontinuation
- 2006-09-27 JP JP2008533628A patent/JP2009510095A/ja not_active Withdrawn
- 2006-09-27 CA CA002624096A patent/CA2624096A1/en not_active Abandoned
- 2006-09-27 GT GT200600441A patent/GT200600441A/es unknown
- 2006-09-27 AU AU2006297208A patent/AU2006297208A1/en not_active Abandoned
- 2006-09-27 TW TW095135772A patent/TW200804325A/zh unknown
- 2006-09-27 CN CNA2006800360246A patent/CN101277941A/zh active Pending
- 2006-09-27 BR BRPI0616462-5A patent/BRPI0616462A2/pt not_active IP Right Cessation
- 2006-09-27 US US11/528,792 patent/US7601744B2/en not_active Expired - Fee Related
- 2006-09-27 RU RU2008110082/04A patent/RU2008110082A/ru not_active Application Discontinuation
- 2006-09-27 EP EP06815744A patent/EP1934193A1/en not_active Withdrawn
- 2006-09-27 AR ARP060104235A patent/AR055660A1/es unknown
- 2006-09-27 WO PCT/US2006/037962 patent/WO2007041258A1/en not_active Ceased
- 2006-09-27 KR KR1020087007611A patent/KR20080050453A/ko not_active Withdrawn
-
2008
- 2008-03-10 NO NO20081235A patent/NO20081235L/no unknown
- 2008-03-18 IL IL190273A patent/IL190273A0/en unknown
- 2008-03-20 EC EC2008008300A patent/ECSP088300A/es unknown
- 2008-03-26 CR CR9829A patent/CR9829A/es not_active Application Discontinuation
- 2008-03-28 ZA ZA200802774A patent/ZA200802774B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7601744B2 (en) | 2009-10-13 |
| CR9829A (es) | 2008-04-28 |
| GT200600441A (es) | 2007-09-19 |
| AU2006297208A1 (en) | 2007-04-12 |
| EP1934193A1 (en) | 2008-06-25 |
| CN101277941A (zh) | 2008-10-01 |
| RU2008110082A (ru) | 2009-11-10 |
| TW200804325A (en) | 2008-01-16 |
| AR055660A1 (es) | 2007-08-29 |
| ECSP088300A (es) | 2008-04-28 |
| KR20080050453A (ko) | 2008-06-05 |
| ZA200802774B (en) | 2009-01-28 |
| PE20070544A1 (es) | 2007-07-26 |
| JP2009510095A (ja) | 2009-03-12 |
| BRPI0616462A2 (pt) | 2011-06-21 |
| US20070072918A1 (en) | 2007-03-29 |
| NO20081235L (no) | 2008-06-20 |
| IL190273A0 (en) | 2009-09-22 |
| WO2007041258A1 (en) | 2007-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |