CA2614105A1 - Carboxamides d'oxazolidinone contenant de l'azetidine et du cyclobutane utilises en tant qu'agents antibacteriens - Google Patents

Carboxamides d'oxazolidinone contenant de l'azetidine et du cyclobutane utilises en tant qu'agents antibacteriens Download PDF

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Publication number
CA2614105A1
CA2614105A1 CA002614105A CA2614105A CA2614105A1 CA 2614105 A1 CA2614105 A1 CA 2614105A1 CA 002614105 A CA002614105 A CA 002614105A CA 2614105 A CA2614105 A CA 2614105A CA 2614105 A1 CA2614105 A1 CA 2614105A1
Authority
CA
Canada
Prior art keywords
oxo
oxazolidine
compound
carboxamide
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002614105A
Other languages
English (en)
Inventor
Mikhail Fedorovich Gordeev
Vara Prasad Venkata Nagendra Josyula
Adam Robert Renslo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co LLC
Original Assignee
Pharmacia & Upjohn Company Llc
Mikhail Fedorovich Gordeev
Vara Prasad Venkata Nagendra Josyula
Adam Robert Renslo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Company Llc, Mikhail Fedorovich Gordeev, Vara Prasad Venkata Nagendra Josyula, Adam Robert Renslo filed Critical Pharmacia & Upjohn Company Llc
Publication of CA2614105A1 publication Critical patent/CA2614105A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA002614105A 2005-07-06 2006-06-26 Carboxamides d'oxazolidinone contenant de l'azetidine et du cyclobutane utilises en tant qu'agents antibacteriens Abandoned CA2614105A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69673505P 2005-07-06 2005-07-06
US60/696,735 2005-07-06
PCT/IB2006/001835 WO2007004037A1 (fr) 2005-07-06 2006-06-26 Carboxamides d'oxazolidinone contenant de l'azetidine et du cyclobutane utilises en tant qu'agents antibacteriens

Publications (1)

Publication Number Publication Date
CA2614105A1 true CA2614105A1 (fr) 2007-01-11

Family

ID=37309094

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002614105A Abandoned CA2614105A1 (fr) 2005-07-06 2006-06-26 Carboxamides d'oxazolidinone contenant de l'azetidine et du cyclobutane utilises en tant qu'agents antibacteriens

Country Status (4)

Country Link
EP (1) EP1902048A1 (fr)
JP (1) JP2009500389A (fr)
CA (1) CA2614105A1 (fr)
WO (1) WO2007004037A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110092309A (ko) 2008-11-20 2011-08-17 파나세아 바이오테크 리미티드 신규 항균제
WO2010150281A2 (fr) 2009-06-26 2010-12-29 Panacea Biotec Ltd. Nouveaux azabicyclohexanes
EP2765858B1 (fr) 2011-10-13 2016-08-03 Merck Sharp & Dohme Corp. Antagonistes d'un récepteur des minéralocorticoïdes
EP2765859B1 (fr) 2011-10-13 2017-01-18 Merck Sharp & Dohme Corp. Antagonistes de récepteur des minéralocorticoïdes
WO2013055607A1 (fr) * 2011-10-13 2013-04-18 Merck Sharp & Dohme Corp. Antagonistes d'un récepteur des minéralocorticoïdes
EA202190167A1 (ru) 2015-07-17 2021-07-30 Зе Глобал Эллайенс Фо Тб Драг Девелопмент, Инк. Замещенные фенилоксазолидиноны для антимикробной терапии

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ291847B6 (cs) * 1994-10-26 2003-06-18 Pharmacia Upjohn Company Antimikrobiální fenyloxazolidinony
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
BRPI0413838A (pt) * 2003-08-25 2006-10-24 Warner Lambert Co compostos de ariloxazolidinona antimicrobianos

Also Published As

Publication number Publication date
JP2009500389A (ja) 2009-01-08
EP1902048A1 (fr) 2008-03-26
WO2007004037A1 (fr) 2007-01-11

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FZDE Dead