CA2604349A1 - Procede pour identifier des modulateurs de la pde10 - Google Patents

Procede pour identifier des modulateurs de la pde10 Download PDF

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Publication number
CA2604349A1
CA2604349A1 CA002604349A CA2604349A CA2604349A1 CA 2604349 A1 CA2604349 A1 CA 2604349A1 CA 002604349 A CA002604349 A CA 002604349A CA 2604349 A CA2604349 A CA 2604349A CA 2604349 A1 CA2604349 A1 CA 2604349A1
Authority
CA
Canada
Prior art keywords
amino acid
seq
domain
adenylate cyclase
gaf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002604349A
Other languages
English (en)
Inventor
Joachim Schultz
Jost Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2604349A1 publication Critical patent/CA2604349A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002604349A 2005-02-28 2005-05-18 Procede pour identifier des modulateurs de la pde10 Abandoned CA2604349A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102005009773 2005-02-28
DE102005009773.1 2005-02-28
DE102005009849.5 2005-03-01
DE102005009849 2005-03-01
PCT/EP2005/052271 WO2006092174A1 (fr) 2005-02-28 2005-05-18 Procede pour identifier des modulateurs de la pde10

Publications (1)

Publication Number Publication Date
CA2604349A1 true CA2604349A1 (fr) 2006-09-08

Family

ID=35064635

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002604349A Abandoned CA2604349A1 (fr) 2005-02-28 2005-05-18 Procede pour identifier des modulateurs de la pde10

Country Status (8)

Country Link
EP (1) EP1856253A1 (fr)
JP (1) JP2008531024A (fr)
KR (1) KR20070116015A (fr)
AU (1) AU2005328604A1 (fr)
CA (1) CA2604349A1 (fr)
IL (1) IL185086A0 (fr)
NO (1) NO20074815L (fr)
WO (1) WO2006092174A1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3307999A (en) * 1998-02-23 1999-09-06 Icos Corporation Phosphodiesterase 10

Also Published As

Publication number Publication date
IL185086A0 (en) 2007-12-03
JP2008531024A (ja) 2008-08-14
WO2006092174A1 (fr) 2006-09-08
EP1856253A1 (fr) 2007-11-21
AU2005328604A1 (en) 2006-09-08
KR20070116015A (ko) 2007-12-06
NO20074815L (no) 2007-11-08

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Legal Events

Date Code Title Description
FZDE Discontinued